New gene reduces retinal degeneration in fruit flies
...al degeneration caused by a different mutant. They named this new gene Lazaro after the novel Lazarillo de Tormes, in which the orphan boy Làzaro helps a blind man see. Of the molecules known to control TRP channels, a key player is diacylglycerol, known as DAG. DAG is known to be made by a well-studied b...FSU biologist says new dinosaur is oldest cousin of Tyrannosaurus rex
...annosaur's predatory family. The creature has been named "Guanlong wucaii" and translated loosely from Chinese, that's "crowned dragon five colors." An internationally known expert on the development and evolution of the vertebrate musculoskeletal system, Erickson helped confirm the tyrannosauroid lineage...New antimicrobial compound adheres to skin to promote healing
... using the compound to heal skin ulcers on a whale named Gasper who was rescued from a Mexico City amusement park and is now a popular resident of the Georgia Aquarium. Petroleum-based ointments are commonly used in treating skin infections, but Capomacchia said that petroleum can be toxic and inhibit he...Salk researchers make fast strides towards understanding how our body controls walking
...enetic approaches to identify a subset of neurons, named V1 neurons, as being part of the CPG, and gene targeting methods to selectively disable them in order to observe what happens. "It allowed us to peer into this black box that is the central pattern generator," explained Lanuza. V1 neurons are so-ca...BioMed Central launches Biology Direct
...ect will operate completely open peer review, with named peer reviewers' reports published alongside each article. The journal also takes the innovative step of requiring that the author approach Biology Direct Editorial Board members directly to review the manuscript. The journal, available online at ww...Groovy protein essential for promoting cancer development
...s first discovered -- would work. The researchers named the protein fragment "telomerase essential N-terminal" (TEN) domain, in reference to its position within the complete enzyme. It took a few more biochemical tricks, but eventually Jacobs crystallized the protein fragment and analyzed it using x-ray d...Report lists top 20 most-vulnerable African carnivores
...s first discovered -- would work. The researchers named the protein fragment "telomerase essential N-terminal" (TEN) domain, in reference to its position within the complete enzyme. It took a few more biochemical tricks, but eventually Jacobs crystallized the protein fragment and analyzed it using x-ray d...Where 'jumping genes' fear to tread
...in humans, 993 in mice, and 559 in opossums. They named these segments TFRs, or transposon-free regions. "Strikingly," says Mattick, "many TFRs in the human genome occur in the same position in the mouse and opossum genomes, despite the fact that transposons entered each lineage independently, after each...Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor
...multi-pigmented skin disease by a Hungarian doctor named Moritz Kaposi in 1872, it was considered to be quite rare--a medical curiosity usually found in particular populations such as older Italian men, transplant patients and young men in certain parts of sub-Saharan Africa. But then at the dawn of the AI...Hepatitis C therapy: Inhibiting newly discovered microDNA molecule
...t the hepatitis C virus needs a specific microRNA, named miR-122, in order to replicate in cultured liver cells. When the scientists inactivated the microRNA, the amount of hepatitis C virus RNA was reduced by approximately 80 percent. The discovery was widely heralded for its potential to develop new ...Mystery solved: Gold's power against autoimmune diseases defined
...y in diseased tissues. In 1890, a German doctor named Robert Koch found that gold effectively killed the bacteria that caused tuberculosis. In the 1930s, based on a widely held but probably erroneous connection at the time between tuberculosis and rheumatoid arthritis, a French doctor, Jacques Forestier...New human retrovirus originated in mice
...n foreign cells other than mouse cells. Thus, they named the virus, Xenotropic MuLV-related virus, or XMRV. "This finding was a big surprise because most of these endogenous viral genomes have undergone such mutation and deletion that they are incapable of giving rise to viruses any more," said Ganem. "An...Progress being made in exploring potential use of stem cells to treat heart disease
...egenerative cardiac therapies," says Ivey, who was named in April one of seven current postdoctoral fellows participating in the Gladstone's new stem cell training program, funded by the California Institute for Regenerative Medicine. "The adult heart seems to have reservoirs of cardiac progenitor cells--a...Technique speeds up detecting, treating wound bacteria
...s, including one, Finegoldia magna, which had been named after him in the past. A World War II and Korean War veteran who confesses he's had an "ongoing love affair with anaerobes for several decades," Finegold has two additional eponymous bacteria--Alistipes finegoldia and Bacteroides finegoldii--that wil...New genes implicated in rheumatoid arthritis
...on of 1,163 transcripts, representing 827 uniquely named genes. Of this total, 3 genes were significantly over-expressed in the cells of RA patients relative to their healthy co-twins. The most significantly over-expressed gene was laeverin, a newly discovered enzyme that works to degrade proteins. The ...Studies suggest new brain protein may help in treating schizophrenia, insomnia and anxiety
... Pittsburgh June 19 ?22. Neuropeptide S (NPS), so named by Rainer K. Reinscheid, Ph.D., assistant professor, Program in Pharmaceutical Sciences, University of California, Irvine, is produced by a small cluster of cells in the brainstem, yet its specialized receptors are found in several areas of the brain...NASA technology helping injured US troops
...D.C. The revolutionary new physical therapy device named SAM, for the Secure Ambulation Mode, is based on technology originally developed and honed at NASA's Goddard Space Flight Center in Greenbelt, Md. The late James Kerley created and patented the technology, consisting of short segments of flexible ...'Sticky' mice lead to discovery of new cause of neurodegenerative disease
...e with a mutation called sticky (sti). Although named for the sticky appearance of their fur, the mice harbor much more serious problems beneath their unkempt coats: poor muscle control, or ataxia, due to death of Purkinje cells in a region of the brain called the cerebellum. No one knew why Purkinje...When it comes to gene transcription, random pauses aren’t quite so random, study finds
...reverses direction briefly; or a "hairpin pause, " named for tiny hairpin-shaped structures that sometimes form when an RNA strand binds to itself. "Kristina made these totally cool DNA templates that have the same 240-base pair sequence repeated over and over again eight times in a row," Block said. When...... on a possible example: a form of inherited anemia named beta-thalassemia, which occurs when a mutant beta hemoglobin gene results in faulty production of hemoglobin. The new study suggests it might be possible to use regulatory sequences from the faulty gene to activate a similar gene, essentially creatin...