Most common lung cancers may begin in newly discovered cells
...-authors first isolated the stem cells, which they named bronchioalveolar stem cells (BASCs), from the earliest stage of the mouse tumors. Then, she purified them from the lungs of healthy mice. On the surface of BASCs, Bender Kim found another protein marker that is also present on the surface of better-s...Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure
...ld be used as the basis for new drugs. The enzyme, named Orf2, takes chemical building blocks known as small aromatic molecules and changes them by adding a fat-like molecule called a prenyl group. That modification can have a huge impact on where the aromatic molecule goes within the cell, and what sort o...Stem cell training program to make its Stanford debut
...ld be used as the basis for new drugs. The enzyme, named Orf2, takes chemical building blocks known as small aromatic molecules and changes them by adding a fat-like molecule called a prenyl group. That modification can have a huge impact on where the aromatic molecule goes within the cell, and what sort o...Beyond genes: Lipid helps cell wall protein fold into proper shape
...oli, is affected by the presence of a phospholipid named phosphatidylethanolamine, or PE for short. Phospholipids, unlike their fatty acid and cholesterol cousins, include a phosphate group that spurs them to form a bilayer with water-friendly outer layers sandwiching an impermeable water-unfriendly inner...Researchers identify new catfish family
...in Zootaxa, an online scientific journal. They've named the new family Lacantuniidae and named the species Lacantunia enigmatica. It becomes the 37th family of catfishes, a diverse group of fish ...Researchers create infectious hepatitis C virus in a test tube
...ther cells. Lindenbach, Rice and their colleagues named their infectious cell culture virus HCVcc. Already HCVcc is yielding new knowledge about HCV. In a separate set of experiments, the researchers used HCVcc to confirm that a molecule called CD81, which sits on the surface of the human cell membrane, p......ink.asp?id=4elc7n9j2au5tb95. McMaster University, named Canada's Research University of the Year by Research InfoSource, has world-renowned faculty and state-of-the-art research facilities. McMaster's culture of innovation fosters a commitment to discovery and learning in teaching, research and scholarshi...Virginia Tech, Nanjing Institute researchers discover half-billion year-old fossils
...the week of July 11 - 15, 2005. Ediacara fossils, named after Ediacara Hill in the Flinders Ranges of South Australia where such fossils are best known, are some of the oldest fossils with large body size and complex morphology. "Present in rocks ranging from 575 to 540 million years in age, these fossils...Exercise aside, genes may ultimately dictate seniors' mobility
... population possesses the DD genotype of the gene, named for the angiotensin-converting enzyme, or ACE. The rest have the II or ID versions of the ACE gene. Study participants were categorized according to their exercise intensity and their genetic makeup. Overall, about 41 percent of study participants b...Scientists find a maturity gene in fly
...rol metamorphosis in response to a steroid hormone named ecdysone, which is emitted by a gland as the larval stages end. When the gene was disabled, the fly larvae started metamorphosis but died within 12 hours. In some, their heads failed to emerge from their bodies. "How does an animal know when it is r...MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools
...rol metamorphosis in response to a steroid hormone named ecdysone, which is emitted by a gland as the larval stages end. When the gene was disabled, the fly larvae started metamorphosis but died within 12 hours. In some, their heads failed to emerge from their bodies. "How does an animal know when it is r...Neurotransmitters signal aggressive cancer, offer potential for early diagnosis
...ers. One of those "communication chemicals," aptly named GABA (gamma amino butyric acid), shows up in unusually high amounts in some aggressive tumors, according to a new study from Washington University School of Medicine in St. Louis. The researchers investigated metastatic neuroendocrine tumors, which ...UT Southwestern researchers discover master switch in cell death
...ewly discovered enzyme, which the researchers have named Mule, destroys a key molecule at the top of the pyramid, thus leading to the cascading disintegration of the cell. Their findings also suggest a new drug target for controlling tumor formation. Dr. Xiaodong Wang, professor of biochemistry at UT Sout...Scientists get first glimpse at how plants, most animals repair UV-damaged DNA
...he enzyme that was responsible for the repair, and named it photolyase, but they didn't know exactly how the enzyme worked. By the 1980s, scientists proposed a mechanism for photolyase ?that it donated an electron to damaged DNA ?but nobody could prove it. The reaction happened too fast to be seen with no......bs. The new study deals with how one such protein, named Ets-1, turns genes on or off. Huntsman Cancer Institute scientists, led by Barbara Graves, Ph.D., professor and chair of the Department of Oncological Sciences at the University of Utah School of Medicine, and doctoral student Miles Pufall, studied ...US/African project deciphers deadly parasite genome
...gnificant discoveries about the parasite, which is named for him. Vish Nene, a former ILRI scientist who came to TIGR in 2001 to join the T. parva project, says the genome sequence provides useful information that will help scientists better understand how the parasite malignantly transforms cattle white ...An essential regulator of body weight revealed
... make up the arcuate nucleus are NPY/AgRP neurons, named for two proteins they produce, neuropeptide Y (NPY) and agouti-related protein (AgRP). Researchers have long suspected NPY/AgRP neurons to be important regulators of feeding behavior, acting in opposition to POMC neurons to stimulate appetite. But ge...Plant gene related to cancer treatment may foster new oncology drugs
... regulate those reactions. The ABC proteins are so named because they must bind with ATP, the main cell energy source, in order to fulfill their mission. The best known member of another class of transport proteins, PIN1, also may be a transporter, but appears to function primarily as an aide rather than ...Ancient anthropoid origins discovered in Africa
...ublished their discovery of the two new species -- named Biretia fayumensis and Biretia megalopsis -- in an article in the October 14, 2005, issue of the journal Science. First author on the paper was Erik Seiffert of the University of Oxford and Oxford University Museum of Natural History. Other co-author......und that was isolated in the greatest abundance -- named bromophycolide A by the researchers -- killed human tumor cells by inducing programmed cell death (called apoptosis), a mechanism that is promising for development of new anti-cancer drugs, researchers noted. The findings on three of these compounds...