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Tag: "mutations" at biology news

New gene scanning technology marks a major advance in disease research

...en successfully applied to search for rare genetic mutations in the population at large. Their method, called ...,000 middle-aged individuals, they found some rare mutations associated with very high cholesterol, some with moderately high cholesterol and some with no effect...

miRNAs and musculature

...ganism and advocates the study of loss-of-function mutations in miRNA genes as an essential tool for identifying the biological roles of miRNAs. ...

Lactose intolerance linked to ancestral environment

...lived where dairying flourished and passed on gene mutations that maintain lactase into adulthood. The research, he said, is an example of Darwinian medicine, a new interdisciplinary field of science that takes an evolutionary look at health, and considers why, rather than how, certain conditions or symptoms d...

Genetic link confirmed between Polynesians and indigenous Taiwanese

...n, and Polynesian populations share three specific mutations in their mtDNA that do not occur in mainland east ... they showed that there are enough different mtDNA mutations between the mainland Chinese population and the aboriginal Taiwanese to support archeological findin...

High-Throughput GoMiner

...n, and Polynesian populations share three specific mutations in their mtDNA that do not occur in mainland east ... they showed that there are enough different mtDNA mutations between the mainland Chinese population and the aboriginal Taiwanese to support archeological findin...

Neurotransmitters signal aggressive cancer, offer potential for early diagnosis

...lution in medicine to be a DNA-centered search for mutations in genes that cause disease. This study illustrates another layer of the revolution - understanding how certain diseases, in this case cancer, are linked to abnormalities in cellular metabolism - an area called 'metabolomics'. We've described a uniqu...

Nanotechnology to provide portable genetic risk detection

...ype of the system will initially be used to detect mutations of the BRCA1 gene that are responsible for between...amily history of breast cancer. To detect genetic mutations the OPTONANOGEN system uses an array of 20 microcantilevers coated in nucleic acid that react when t...

UT Southwestern researchers discover master switch in cell death

...issue from cancer patients to try to determine how mutations in the enzyme’s gene may relate to cancer. “We think this gene will really be a hot spot in research,?said Dr. Qing Zhong, postdoctoral researcher in biochemistry at UT Southwestern and lead author of a paper to be published in the July 1 issue of t...

Scientists get first glimpse at how plants, most animals repair UV-damaged DNA

...t DNA from replicating properly, and cause genetic mutations that lead to diseases such as cancer. In cell nuclei that contain photolyase, the enzyme forms a water-filled pocket with the right shape and size to accommodate the dimer for the repair. Normally, the enzyme wouldn't be able to reach the dimer, whi...

Drug resistant avian influenza viruses more common in Southeast Asia than North America

... of the paper. "The specific amantadine-resistance mutations in M2 that we identified can occur randomly throug... in Southeast Asia, and especially in China, these mutations are undergoing strong selective pressure." Selective pressure refers to the extent to which an orga...

Study findings offer potential new targets for antibiotics

...genes into E. coli cells and looked for those rare mutations that could interfere with cell growth. It was known from previous studies that such deleterious mutations occurred within critical regions of the ribosome. After identifying dozens of deleterious mutations...

Defective Gene Linked to Two Inherited Immune Deficiencies

...’s Hospital Boston. The Boston team found specific mutations in a gene known as TACI, which plays a specific ro...er type of antibody, immunoglobulin G (IgG). TACI mutations interfere with two aspects of the immune response that involve maturation of B cells. Normally, TACI...

Human brain is still evolving

...) - across different human populations. In humans, mutations in either of these genes can render the gene nonfunctional and cause microcephaly - a clinical syndrome in which the brain develops to a much smaller size than normal. In earlier studies of non-human primates and humans, Lahn and his colleagues dete...

Agreement will speed research on microbicides for women

...’s Hospital Boston. The Boston team found specific mutations in a gene known as TACI, which plays a specific ro...er type of antibody, immunoglobulin G (IgG). TACI mutations interfere with two aspects of the immune response that involve maturation of B cells. Normally, TACI...

Biologists Crack Genetic Code for Specialized Spider Silk

...’s Hospital Boston. The Boston team found specific mutations in a gene known as TACI, which plays a specific ro...er type of antibody, immunoglobulin G (IgG). TACI mutations interfere with two aspects of the immune response that involve maturation of B cells. Normally, TACI...

An essential regulator of body weight revealed

...the circuits are the same." And he speculates that mutations in human genes that affect the survival of these neurons or their ability to respond to hormonal signals could alter eating behavior and body weight regulation. Now that his lab has demonstrated that NPY/AgRP neurons are critical for feeding in adul...

DNA size a crucial factor in genetic mutations, study finds

... to heap negative connotations onto the term, some mutations create new traits that actually benefit the organi...ing enzyme efficiency-and a mechanism for allowing mutations into the DNA molecule. ''It's a way the organism can evolve,'' Kool says. ''If the protein that cop...

New study to explore cellular circuitry

...in principle, work around self-destructive genetic mutations in cells on the way to treating many diseases with genetic roots," said Grayhack, a co-developer of the library along with Phizicky, Mark Dumont, Ph.D., associate professor in the department and researchers at Yale led by Michael Snyder, Ph.D. ...

Studies on human genome variation provide insight into disease

...e of which may have resulted in the development of mutations involved in prostate cancer susceptibility. "Bec...ips of all these partners to focus on real disease mutations and to minimize attention on the innocent gene variants that colour the humanity of life." ...

Housecat-sized Siberian tiger cubs get collared

...e of which may have resulted in the development of mutations involved in prostate cancer susceptibility. "Bec...ips of all these partners to focus on real disease mutations and to minimize attention on the innocent gene variants that colour the humanity of life." ...

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