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Tag: "mutant" at biology news

Past experience of pheromones induces dominant courtship behavior in fruit flies

...rly encounter. To prove this, the researches used mutant flies that lack the normal adult pheromones, and they covered these pheromone-defective flies with a variety of other smells. The researchers were able to demonstrate that a male shows courtship dominance behavior over young males if he has been expo...

New study examines how sense of smell affects mating and aggression in mice

...In the study, researchers compared the behavior of mutant male mice that had been genetically modified to di... cages with the male mutants. When comparing the mutant males with wild-type males, study results showed that all wild-type males mated with test females, w...

How Fruitflies Know It's Time for Lunch

...eating behavior. One group of these flies shared a mutant klumpfuss (klu) gene, normally responsible for enc... microarrays, Melcher and Pankratz discovered that mutant fly larvae overexpress the hug gene, which is known to encode at least two neural proteins related t...

Algal protein in worm neurons allows remote control of behavior by light

...g behavior to occur (in response to light) even in mutant worms that lacked the C. elegans ion channel that normally mediates backing behavior in response to touch. The researchers performed electrophysiological experiments to show that the effects they observed were indeed due to the inward flow of ions c...

Greasing interferon's gears may pave way to greater therapeutic benefits, fewer side effects

... effects," Holtzman says. The group engineered a mutant Stat1 protein in which the identities of two amino acids were switched. Investigations conducted on cells growing in culture showed that the altered Stat1 proteins reacted more efficiently to the presence of both type I and type II interferons. Furth...

Harnessing genomic research

...ring infection is using this knowledge to generate mutant bacterial strains that may be useful as vaccines. Experiments under way have shown several mutant bacterial strains to be highly effective as vaccines. In comparative studies one of the new strains ...

ORNL leading effort to help harness power of Shewanella

...t DOE waste sites, characterization of in situ and mutant physiologies and exploration of conditions conducive to optimal reduction of metals. This is one of six recently announced DOE projects aimed at increasing knowledge of microbes and microbial communities with potential applications in bioremediation...

Olfactory system detects pheromones that control reproduction

...ucing neurons. They studied the sexual behavior of mutant mouse strains that lacked either a functional olfactory epithelium or vomeronasal organ. They also studied the behavior of normal mice in which the olfactory epithelium had been selectively destroyed by a drug. They found that the male mice that lac...

UCLA discovery will aid in treatment of patients with a deadly brain cancer

... telltale molecular signature ?the expression of a mutant protein and the presence of a tumor suppressor pro...might be the interaction of the PTEN protein and a mutant protein called EGFRvIII. About half of patients with amplified EGFR also have this mutant protein. ...

Technique offers new view of dynamic biological landscape

...y to quantify the epistatic effects of interacting mutant genes on the cells' viability. Since yeast form ro...en grown in culture dishes, they could measure the mutant cells' colony size in an automated fashion and use that to calculate their growth rates. To determin...

The secret love life of plants

...he University of Cologne have, however, isolated a mutant where there is only one single fertilisation. In a...Cologne, working with Arp Schnittger, have found a mutant of the plant Arabidopsis thaliana called cdc2. It has an altered pollen. Because of a failed cell di...

DNA gene vaccine protects against harmful protein of Alzheimer's disease

...f the Neurological Sciences. The researchers used mutant mice with two defective human genes associated wit... As controls, the researchers also either injected mutant mice with the gene for a related but harmless protein, amyloid-beta 16, or with a gene vaccine that ...

Simple idea to dramatically improve dengue vaccinations

...s can leave us more vulnerable to infection from a mutant strain or a related virus. The immune system may respond less favorably in these cases than if it had never been exposed to the disease in the first place." Original antigenic sin, or immunodominance, arises out of the procedure the immune system us...

Evolutionary biology research techniques predict cancer

...verse tumors have a high probability of generating mutant cells that will flourish and spread, allowing the tumor to transform and grow. In the future, in addition to serving as a biomarker for cancer risk, he adds, measures of genetic diversity might help doctors assess the success of cancer prevention the...

Researchers create pigs that produce heart-healthy omega-3 fatty acids

...verse tumors have a high probability of generating mutant cells that will flourish and spread, allowing the tumor to transform and grow. In the future, in addition to serving as a biomarker for cancer risk, he adds, measures of genetic diversity might help doctors assess the success of cancer prevention the...

Flesh-eating bacteria escape body's safety net

...g fasciitis. "Deprived of this single enzyme, the mutant Strep strain was easily killed by human neutrophil... UCSD department of pediatrics. "In addition, the mutant Strep bacteria no longer produced a spreading infection when injected into the skin of experimental ...

Study finds drug may cut down involuntary movements

... known as medium spiny neurons are killed off by a mutant protein. The disease brings with it an array of other difficulties as well, including cognitive problems, changes in personality, and psychiatric problems like depression. As many as one-quarter of patients with the disease attempt suicide, and man...

The evolution of food plants: Genetic control of grass flower architecture

...ient content in cereal grasses. The ramosa2 (ra2) mutant of maize has increased branching of inflorescences...alysis of gene expression in a number of different mutant backgrounds placed ra2 function upstream of other genes that regulate branch formation. The early ex...

Darkness unveils vital metabolic fuel switch between sugar and fat

...ural, or "wild type," genomes and three strains of mutant mice with impaired circadian rhythms. The wild-type mice and two of the mutant strains exposed to regular light-dark cycles showed no sign of the gene's expression in their livers...

Gene therapy 'turns off' mutation linked to Parkinson's disease

...k of Parkinson's disease. Research has shown that mutant forms of the alpha-synuclein gene, as well as too much alpha- synuclein protein, are involved in the development Parkinson's disease in some families. For this research, the Bohn lab combined a recently developed technology called "RNA interference"...

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