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Tag: "must" at biology news

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...icers oversee all research in the GMP suite, which must follow stringent federal guidelines for reintroduction of manipulated cells into the human body. In addition, UCLA's Jonsson Cancer Center features an established clinical trials infrastructure that could be used to test new therapeutics that may de...

Wisconsin researchers identify sleep gene

...nd potassium channels. And we know that slow waves must be generated by changes in the excitability of neuron cell membranes," Cirelli says. "Potassium changes may have a huge affect on sleep in humans." Sleep is a highly complex activity and probably involves many genes, some of which are more influent...

Camera Traps Catch Eye of the Tiger

...the team can check all 30 within a month). Cameras must be moved occasionally because the flash often alerts animals to their presence, causing those animals to avoid the area in the future. Due to the moist, hot climate of Sumatran forests, the cameras often malfunction, so scientists will be lucky if t...

Polymers with copper show promise for implanted sensors

...issues," he said. In addition, the polymer coating must be very thin for most biomedical applications, which limits the amount of nitric oxide that can be stored and released from the thin coating on the sensor surface. The new approach is to make polymers that generate nitric oxide from compounds called...

NIH Calls on Scientists to Speed Public Release of Research Publications

...id growth in the public's use of the Internet, NIH must take a leadership role in making available to the public the research that we support," said NIH Director Elias A. Zerhouni, M.D. "While this new policy is voluntary, we are strongly encouraging all NIH-supported researchers to release their publishe...

Biodiversity hotspots identify conservation priorities

...ernational (CI) and co-editor of the new book. "We must now act decisively to avoid losing these irreplaceable storehouses of Earth's life forms." Nearly 400 specialists contributed to the four-year-long hotspots reappraisal. Their analysis has resulted in an increase in the number of hotspots from 25 to...

A human parasite with a streamlined mitochondrion

...le carrier in the Entamoeba mitosome means that it must be able to do far fewer jobs than our own mitochondria. Further experiments performed by the team reveal that the Entamoeba carrier can only transport ADP and ATP, suggesting that it could fuel energy-requiring reactions within the mitosome but might...

50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

...he said, "but now we know where to look and why we must go there. SUMO may very well act on other ion channels that have yet to reveal their function because they were silent like K2P1." Other membrane proteins key to biology, like transporters and hormone receptors, may also be controlled by SUMO since ...

WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas

...agnosis - persons suspected of having dengue fever must see a doctor at once. Dengue haemorrhagic fever is a deadly disease and early recognition and treatment can save lives. Unless proper treatment is given promptly, the patient may go into shock and die. * Severe abdominal pains (black stools), ble...

Key mechanism in genetic inheritance during cell division identified

...Barnes and Drubin, among others, that kinetochores must bind to a microtubule spindle to avoid the gain or loss of chromosomes by each of the daughter cells. How this works, however, was unknown. To find answers, the Berkeley researchers used a purified, reconstituted Dam1 complex, obtained from genetica...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...half of its life cycle in a tick," he said. "There must be subsets of genes important to its survival there. If it can't exist in ticks, it can't maintain itself in nature and hence can't infect animals or humans." UT Southwestern molecular microbiology graduate student Andrew Revel, a lead author of the...

Computational Method Speeds Mapping of Cell Signaling Networks

... 22 issue of Science. To function properly, cells must be able to detect changes in the environment and respond accordingly--usually by altering their behavior in some way. Cells are equipped with a sophisticated communications network that links surveillance with response, and allows the cells to perfor...

Microbial forensics: The next great forensic challenge

...al prosecutions or those at the national level, we must be sure that the methods and results will be admissible in court, and must be accepted by senior government decision makers." Murch and other scientists point to many challen...

Nanoparticles offer new hope for detection and treatment

...uld work for most solid tumors, because all tumors must recruit new blood vessels to obtain nutrients as they grow. Nevertheless, melanoma has unique traits that make it especially interesting as a target for nanoparticle therapy. Melanoma has a horizontal phase, when it spreads across the skin surface, ...

Brain-mapping technique aids understanding of sleep, wakefulness

...agisawa said. "In order to fall sleep, you somehow must inhibit these orexin neurons. It appears that slee...en one group of neurons is active, the other group must be inactive, and vice versa. It's a seesaw, or flip-flop, mechanism. That's important because you do...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

... life as red and white cells and platelets die and must be replaced. HSCs are also needed to rebuild the blood system of patients undergoing chemotherapy and radiation for cancer. Opferman completed work on this project while a member of Stanley Korsmeyer's laboratory at the Dana-Farber Cancer Institute (...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...terbirth) following child birth. Adult bone marrow must be harvested from living donors through an invasiv... Kurtzberg. Only four of six cord blood "antigens" must match for a transplant to have a reasonable chance of success, whereas adult bone marrow requires a ...

Genetic defects give the immune system the green light to attack the pancreas

...ot convert food into energy. To sustain life, they must get insulin through injections. The disorder can emerge in childhood, adolescence and even appear in adulthood, but the genetic stage is set beforehand. T-cells play a key role. They are part of the highly complex array of immune cells that normally...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

...stead, researchers have found, a single sperm cell must be injected into a single oocyte, a technique call... were not vitrified. For egg freezing to work, it must be a mature oocyte, which means a woman must have 14 days of hormone treatments to stimulate mature ...

Medical whistleblowers speak out

...evelopment, prescribing, and safety monitoring, we must be willing to examine and change all of the institutions that allow this synchrony to occur." In a related editorial, the PLoS Medicine editors explain why PLoS sponsored the roundtable and why they published Lenzer's account: "Lenzer's report will,...

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