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Tag: "muscle" at biology news

A surprise about our body clock

...th crushing disabilities, mainly because the heart muscle is not able to regenerate after a heart attack. This study identifies the method the body employs to repair the heart and provides new therapies to stimulate cardiac regeneration and prevent heart failure in patients who have suffered a heart attack,...

Healing the heart with bone marrow cells

...th crushing disabilities, mainly because the heart muscle is not able to regenerate after a heart attack. This study identifies the method the body employs to repair the heart and provides new therapies to stimulate cardiac regeneration and prevent heart failure in patients who have suffered a heart attack,...

New understanding of parasite cell structures may provide treatments for serious tropical diseases

...oms of this disorder at birth "may include lack of muscle tone and an inability to move. Other symptoms may include unusual facial characteristics, mental retardation, seizures and an inability to suck and/or swallow. Jaundice and gastrointestinal bleeding may also occur." The new research will open areas ...

Variations in detoxifying genes linked to Lou Gehrig's disease

...tive disorder of the motor neurons that results in muscle weakness, difficulty speaking, swallowing and breathing and eventual total paralysis and death generally within five years. In 1993 Siddique and collaborators determined that mutations in a gene known as SOD1 account for 20 percent of familial, or...

Scientists describe new African monkey genus ?first in 83 years

...00 miles away." The molecular data recovered from muscle tissue and analyzed in detail by Olson shows Kipunji is most closely related to baboons in the genus Papio, and not to Lophocebus, the genus to which Kipunji was originally assigned. The in-depth analysis involved five different genes, including gene...

Drug dials down the energy within cells, UM researchers find

...ransfers it to energy-demanding processes, such as muscle contraction and the transmission of nerve signals. "People had proposed in the past that if you could inhibit this enzyme, there might be therapeutic potential. But the problem is, if you inhibit the enzyme in the way most powerful drugs do, turning...

Taking the wrinkles out of motoneuronal disease

...e a degeneration of the nerve pathways controlling muscle activity. The diseases are severe and physically debilitating disorders which lead toprogressive weakness and wasting of muscles. Many of the diseases are incurable. Dr Meunier is developing botox to selectively deliver drugs to motoneurons to direc...

New study shows antibiotic may protect the heart

...ized in patients to favorably affect damaged heart muscle beyond the blockage causing a heart attack," said George W. Vetrovec, M.D., chair of cardiology at VCU's School of Medicine, and co-author of the study. For the last several years, Kukreja and his colleagues have studied a class of erectile dysfunct...

Proteins as parents

...in Li chose two different titin domains from heart muscle for their experiments. Titin, a giant molecule, is...e, there are differences: The titin found in heart muscle is less tensile than that found in skeletal muscle and it gives the heart the necessary stability to...

UCLA study finds same genes act differently in males and females

...cs. The UCLA team examined brain, liver, fat and muscle tissue from mice with the goal of finding genetic ... a gender difference in gene expression in fat and muscle tissue. Earlier studies have identified roughly 1,000 sex-biased genes in the liver, and other rese...

Gene therapy injected into the brains' of mice with Huntington's disease

... motor function), hind limb clasping behaviors and muscle weakness. One control group of mice did not receive any gene therapy. A second control group was injected with a placebo gene therapy. The third group received the active GDNF gene therapy. To measure fine motor coordination, balance and fatigue, ...

Federal testing for mad cow disease a failure, law review editor says

...iented and clumsy. Eventually the animal loses all muscle control and is unable to walk or eat. No treatment is available. Enforcement of cattle-feed restrictions was placed in the hands of the Food and Drug Administration (FDA) rather than the USDA, which has caused various bureaucratic snarls, including...

Natural pine bark extract relieves muscle cramp and pain in athletes and diabetics

...mely significant for all individuals interested in muscle cramp and pain relief with a natural approach. The...m was hailed as the natural approach for relieving muscle cramps, however studies continue to show magnesium to be inefficient for reducing muscle cramps. "P...

New roles for growth factors: Enticing nerve cells to muscles

...uron diseases such as Lou Gehrig's disease, spinal muscle atrophy, and post-polio syndrome. Failure to estab... in clever and novel ways," Pfaff says. Skeletal muscle consists of thousands of muscle fibers, each controlled by one motor neuron whose cell body lies in ...

Gatekeeping: Penn researchers find new way to open ion channels in cell membranes

...nerve impulse transmission, hormone secretion, and muscle contraction and relaxation. When there are changes to the channel, such as by mutations in a channel gene, disease can result. For example, mutations in some channel genes cause cardiac arrhythmias, including a form of the lethal long QT syndrome. ...

Discovery of agile molecular motors could aid in treating motor neuron diseases

...thing, and swallowing. When these neurons die, the muscle itself atrophies. A well-known motor neuron disease is amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig's disease). Using a specially-constructed microscope that allows researchers to observe the action of one macromolecule at a ti...

'Sticky' mice lead to discovery of new cause of neurodegenerative disease

...serious problems beneath their unkempt coats: poor muscle control, or ataxia, due to death of Purkinje cells in a region of the brain called the cerebellum. No one knew why Purkinje cells were dying in sticky mutant mice. To find out, Ackerman and her colleagues searched for the gene that was disrupte...

Life and death in the hippocampus: what young neurons need to survive

...ult brains live or die depends on whether they can muscle their way into networks occupied by mature neurons. Neuroscientists at the Salk Institute for Biological Studies pin-pointed the molecular survival gear required for a young neuron to successfully jump into the fray and hook up with other cells. I...

New GI technologies improve internal organ visualization

...cific interest for patients who have damaged heart muscle after a heart attack and may benefit from the injection of therapies directly into the muscle without another operation." Endoscopic Ultrasound (EUS)-Guided Angiography: A Novel Approach to D...

Survivors of childhood polio do well decades later as they age

...s. This tells us that the cause for the decline in muscle strength in polio survivors may be aging alone." Polio is a contagious, viral illness that peaked in the United States in 1952, when 3,000 people died of the disease. Mass immunizations in the mid-1950s began to slow the spread of the disease, an...

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