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Tag: "multiple" at biology news

Prenatal Stress Keeps Infants, Toddlers up at Night, Study Says

... that gauged how depressed or anxious they were at multiple points early on in, late in, and after their pregnancy. Later on, the women were then asked to report on their childs sleep habits at 6, 18 and 30 months, detailing how long the child slept (a consolidated daytime and nighttime total), how often the ...

Genomic Analysis Uncovers New Targets for HIV Vaccine

...ustralia. They arrived at 486 patients who had had multiple blood tests documenting viral loads after infection and before they started receiving antiretroviral treatment. The three polymorphisms were identified after all the blood samples of the selected patients were screened for more than 555,000. Additi...

Modeling the restless brain

...ntains rich and interrelated temporal structure at multiple time scales that is shaped by the underlying structural topology," Sporns and Honey wrote in an article appearing this week in the Proceedings of the National Academy of Sciences early edition online. The article, which will be available at http...

Simulations unravel outer membrane transport mechanism

...rchers applied a force to TonB and showed that the multiple hydrogen bonds between TonB and the luminal domain...lations help researchers study the interactions of multiple proteins in complex systems, such as the TonB-dependent transporter, Gumbart said. “As we get mor...

Loss of stem cells correlates with premature aging in animal study

...y need to maintain the integrity of their DNA, and multiple divisions lead to natural breaks in DNA. But when these stem cells are needed, their progeny can rapidly divide and are able to replenish the tissue with new cells. Brown explains that in the current study the mouse cells without ATR had an overw...

Small, self-controlled planes combine plant pathology and engineering

...hnology enables us to have coordinated flight with multiple aircraft. In other words, we can have two aircraft sampling pathogens at the same time but at different altitudes.” Schmale has used the small, self-controlled planes to collect samples of the fungal genus Fusarium tens to hundreds of meters above...

New findings challenge established views on human genome

...e, diverse experiments and then analyze them using multiple computational methods,” said Elise A. Feingold, Ph.D., program director for ENCODE in NHGRI’s Division of Extramural Research, which provided most of the funding for the pilot project....

Herpes virus hijacks DNA repair process

...Kinases are versatile proteins that sometimes play multiple roles. To ensure that enhanced viral replication wasn't linked to orf36's interactions with other molecules, researchers turned to mice lacking the genes for ATM and H2AX, the damage response proteins activated by infection. When they infected cells ...

University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts

...e in very limited supply, as many patients require multiple grafts. Thus, there is an ongoing search for the ideal small-caliber arterial substitute for revascularization procedures. The University of Pittsburgh team, led by David A. Vorp, Ph.D., associate professor of surgery and bioengineering and a facu...

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents

...er and normal stem cells were protected equally by multiple drug resistance transporters, even if the bulk of the tumor responded to chemotherapy. According to Dr. Donnenberg, the very fact that cancers can and do relapse after apparently successful therapy indicates the survival of a drug-resistant, tumor...

Gene responsible for common hearing loss identified for first time

...hat this remained significant after correcting for multiple testing. Analysis of a large French group showed the same association. “Combining the data from both groups with a common odds ratio gave a very significant result, from which we were able to conclude that we were the first to identify a gene tha...

Mutating the entire genome

...expensive because they require researchers to make multiple manipulations in mouse embryonic stem cells, which...0,000 times better. That is important, because multiple molecular steps are needed for a mouse to develop a human cancer – and such mice are used to learn h...

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

...at they can become: more of themselves, as well as multiple different specialized cell types. But as genetic techniques have become increasingly powerful, many scientists have sought a more molecular definition of stem cells, based on the genes they express. Now, a team of Canadian scientists has identified...

Male circumcision overstated as prevention tool against AIDS

...sy to transmit heterosexually, b ut over time with multiple exposures, infection is inevitable. These men then...that individuals in highly infected countries have multiple contacts with the infected so reducing transmission rates only defers the inevitable. The real qu...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

...conditions (e.g. Alzheimer’s disease, dementia and multiple sclerosis). While the just published study involved a technique that delivers gene therapy by injection at the joint, other promising approaches may involve interrupting crosstalk in the brain instead. Based on that promise, the Medical Center i...

Avian influenza survivors' antibodies effective at neutralising H5N1 strain

...e 1918 Spanish H1N1 influenza pandemic, there were multiple reports of physicians administering blood taken from survivors to patients infected with the disease. A recent review suggested that this treatment was associated with a halving in mortality. However, directly administering blood carries a risk of in...

New study suggests potential for a broadly-protective HIV vaccine

...uce cross-reactive antibodies that will neutralize multiple viral strains. These results demonstrate that indu...duce cross-reactive antibodies that can neutralize multiple strains. USU Professors CAPT Gerald Quinnan, Jr., M.D., USPHS, and Christopher Broder, Ph.D., and th...

Lessons from the orangutans: Upright walking may have begun in the trees

...hes. When bipedal, the animals also tended to grip multiple branches with their long toes. On medium-sized ...enture onto thin branches. They could have gripped multiple branches with their toes and distributed their center of gravity more effectively, while keeping one...

Catching cancer's spread by watching hemoglobin

...biopsies, which is especially helpful if there are multiple suspicious areas that need to be investigated. Since hemoglobin is highly concentrated in red blood cells, imaging the locations where this molecule occurs can map out the distribution of red blood cells and reveal the vessels themselves. If the i...

A cherry on top: Tart cherries may alter heart/diabetes factors

...nical Research Center, and have their blood tested multiple times to look for the breakdown products of cherries. ...

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