Genes set scene for metastasis
...eutic treatment. Metastasis ?the leading cause of mortality in cancer patients ?entails numerous biological functions that collectively enable cancerous cells from a primary site to disseminate and overtake distant organs. A number of genes are already known to contribute to the spread of breast cancer cells ...Discovery could lead to better control of hemorrhagic fever viruses
...nd Brazilian hemorrhagic fever, respectively, with mortality rates of about 30 percent. No vaccine is available...able to infection. "This may help explain why mortality is so high," says Choe, the study's senior author. Choe now hopes to translate these findings int...RNA splicing factor implicated in ovarian tumor cell growth
...ers," said He. "Two factors account for the dismal mortality outcomes. One is the absence of reliable early detection markers, and the other is inadequacy of present therapy for advanced disease. To improve patient survival, it is critical to identify new biomarkers for early detection." Polypyrimidine trac...Pitt study notes decline in male births in the US and Japan
...y noted that African-Americans have a higher fetal mortality rate overall and a higher proportion of male fetus...ing since the black-white ratio in terms of infant mortality has remained the same for almost 100 years,?said Lovell A. Jones, Ph.D., study co-investigator and p...UCI scientists reconstruct migration of avian flu virus
...of this flu have been recorded worldwide, its high mortality rate raises concerns that if the virus mutates to where humans can pass it on, a flu pandemic may occur. ...Rapid response was crucial to containing the 1918 flu pandemic
...s that waited just a few weeks to respond. Overall mortality was also lower in cities that implemented early in...ok longer to implement them, and as a result, peak mortality rates were higher. In the most extreme disparity, the peak mortality rate in St. Louis was only one-...DNA analysis suggests under-reported kills of threatened whales
...y twice the number in official reports. "If the mortality is really twice as great as the number reported to.... "The obvious question becomes how much of the mortality is caused by incidental bycatch, and how much of it is actually intentional," Baker said. "Beyond th...Gene thought to assist chemo may help cancer thrive
...ding to tumor recurrence and explaining the higher mortality rate of patients whose tumors had a functioning p53. If we are correct, inhibiting p53 in tumors being treated with chemotherapy may substantially improve patients' long-term survival." McDonald and colleagues are continuing to test their theory b...Parasites' impact goes beyond host to affect ecosystem
...nal status, reproductive abilities, and even their mortality ?but also the hosts?entire ecosystem. In the article, "Parasites alter community structure," lead author Chelsea Wood, then a Dartmouth College undergraduate, and UNH associate professor of zoology James Byers, working at the Shoals Marine Lab of...Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
...Atherosclerosis is the main cause of morbidity and mortality worldwide. Classic risk factors including smoking, diabetes, hypertension and high cholesterol levels are known to play a pivotal role in the pathogenesis of the disease that also recognises a genetic influence. However, it is well known that acute c......on projections and other data on the incidence and mortality of Alzheimer’s. ......s Matt Broadhurst and Paul Butcher have shown that mortality rates can be significantly improved through changed practices. Key recommendations from an initial two-year project are that fishers should Cut the line on fish that swallow hooks Remove hooks caught in the fish’s mouth Minimise air exp...