Eliminate Data Analysis Bottlenecks in Drug Discovery
... its sirtuin relatives, is best known for removing molecular "decorations" on proteins that help organize DNA and restrict access to genes. It turns out that sirtuin1 also removes these decorations from PGC1, and then remains bound to PGC1 as it starts up the sugar-making process, the researchers found. "Beca......us," said Dr. Gad Shaulsky, associate professor of molecular and human genetics at BCM. Microarrays are fairly new technology that can help scientists understand how genes interact as well as how they are regulated by networks within the cell. They are created by the placement of tiny droplets of functional D...Researchers find gene that may be at root of potato blight
...ze ?although they physically look like fungi, on a molecular level they more closely resemble algae. Over the ... researchers knew little about P. infestans on the molecular level. By studying Avr3a, R3a and similar genes, researchers may be able to determine what happens ...Where bacteria get their genes
... Howard Ochman, a UA professor of biochemistry and molecular biophysics and a member of UA's BIO5 Institute. The research also solves a long-standing evolutionary puzzle. Many scientists have argued that drawing traditional family trees does not make sense for bacteria, because their genomes represent a mix o...NHGRI targets 12 more organisms for genome sequencing
...any pesticides. Understanding this resistance at a molecular level can lead to safer and more effective pesticides and improve human nutrition. The genome of the pea aphid, used extensively as an experimental model, will be a valuable comparison with other insects, such as the closely related insect, Rhodnius ...Remote control flies? Fly behavior controlled by laser light
...a that specific nerve cells could be equipped with molecular "receivers" that allow them to recognize an outsid...lish this, Miesenböck and Lima devised a triggered molecular lock and key system, where the "lock" was the receiver genetically encoded to be expressed in the ta...Analysis Of Human Genome To Predict The Development Of Illnesses
...es all known genes and proteins according to their molecular function, molecular composition and biological process. With the unknown ones, they are logged (comparing similarities a...Alcohol consumption disrupts breastfeeding hormones
...eas of: sensation and perception, neuroscience and molecular biology, environmental and occupational health, nutrition and appetite, health and well being, and chemical ecology and communication. For more information about Monell, please visit www.monell.org or email media@monell.org. CITATION: Julie A. Menne...At the molecular level, the predator is the prey
...turning out to be something of an illusion. At the molecular level, another battle rages. And in this second, m...ch other, but not in these snakes. We're finding a molecular arms race is driving rapid and repeated changes in the gene within this group of beasts." For TTX t...Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips
...tivating bacteria is slow and costly. By hijacking molecular synthesis with the latest advances in biotechnology--and inducing bacteria to overproduce antibiotics--Kao aims to greatly speed up drug development. "Companies have proprietary mutant [bacterial] strains that have been worked on for more than 20 ye...Scientists identify genes responsible for 'black rot' disease in vegetables
... metabolic pathways. The researchers hope that the molecular characterization of these pathogenicity-related genes will lead to the development of a treatment for "black rot" disease. Employing whole-genome comparative genomic approaches, the authors sequenced the complete genome of an Xcc strain that was iso......"bioMerieux provides a full range of solutions for molecular diagnostics, from single to multiple and complex genetic targets, requiring the use of microarrays. Our extended agreement with Affymetrix broadens our rights beyond infectious diseases, food and water testing. The potential for microarrays in cancer...Venom doc tracks down snake bioweapons
...odified into toxins where those with a very stable molecular structure ?those that are rich in the amino acid cysteine, which enables proteins to form intramolecular disulfide linkages. "These structures provided an excellent framework for the 60-80 million years of 'evolutionary tinkering' that have turned th...Innovative coating could give medical implants a longer life
...dation or to the body's enzymes. In contrast, the molecular compound developed at Northwestern, which sticks securely to a surface and prevents cell and protein buildup, works for a long period of time. In laboratory studies, the new coating provided effective fouling resistance for more than five months, whi...Atmosphere may cleanse itself better than previously thought
...hat's going on in that spectral region because the molecular systems of interest frequently have weak spectral features there, so they're tough to see," said Francisco, who contributed the study's computations. "The upshot is that a lot of atmospheric models ignore this region altogether, assuming that because...Newly discovered protein an important tool for sleeping sickness research
...tem to kill it. Understanding trypanosomes at the molecular level is key to fighting African sleeping sickness and diseases caused by similar parasites. ...Breakthrough System for Understanding Ocean Plant Life Announced
...tem to kill it. Understanding trypanosomes at the molecular level is key to fighting African sleeping sickness and diseases caused by similar parasites. ...Function of new cancer genes discovered
...is colleagues used genetic screens to discover the molecular mechanism underlying cylindromatosis. Nijman's research revealed that the CYLD protein plays an important role in the NF-kappa B signalling route. This is a cellular communications system which becomes overactive if the CYLD protein is mutated. This ...Determining The Fate Of Cells In The Human Body
...sociate professor of pediatrics and of medical and molecular genetics at the Indiana University School of Medic...ect these errors," said Dr. Firulli, who also is a molecular biologist at the medical school's Herman B Wells Center for Pediatric Research. "From a pediatrics ...Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines
...ise effects a given compound will have on a cell’s molecular components or chemical processes. Using this tool,... been few ways to predict optimal drug design. The molecular targets of many drug candidates are unknown and are often difficult to tease out from among the thou...