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Tag: "molecular" at biology news

Programmable cells: Engineer turns bacteria into living computers

... assistant professor of electrical engineering and molecular biology. Collaborating with researchers at the California Institute of Technology, Weiss and graduate student Subhayu Basu programmed E. coli bacteria to emit red or green fluorescent light in response to a signal emitted from another set of E. coli...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

Experts in bioengineering, imaging, molecular genetics, immunology, ethics, hematology/oncology ...r experts from fields as diverse as engineering to molecular biology, UCLA officials announced March 16 the formation of the Institute for Stem Cell Biology and ...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

...ld one day tailor MS patients' treatments to their molecular profile, and perhaps take some of the uncertainty out of this capricious disease. ...

Wisconsin researchers identify sleep gene

...ed by the circadian system, Tononi notes. "The key molecular mechanisms controlling the circadian timing of sleep are well understood, but details about the homeostatic mechanism that regulates the amount of sleep have been unclear," he says. In a four-year, round-the-clock search, researchers screened 9,000 ...

Controlling protein diversity

... Dr. Bert O'Malley, chair of the BCM department of molecular and cellular biology. The answer is a process called alternative splicing in which certain information from a gene is left out or included, changing the format of the resulting protein. In other words, if the information in a gene is like the elemen...

Molecular models advance the fight against malaria

...me the parasites need to live and multiply -- on a molecular level. With this new understanding of how the parasites were able to counter the effects of atovaquone, researchers can now design new anti-malarial drugs with features making the appearance of resistance more unlikely. "Within the next 3-5 years, w...

Advances in the characterisation of the oyster mushroom genes

...e, has tackled the degradation of cellulose from a molecular perspective. Cellulose is the most abundant biological polymer on the planet. It is made up of units of D-glucose united by means of glycosidic links that form long polymer chains. The breaking down by live organisms takes place through the action o...

Nanoscale Diagnostic Sets Sights on Alzheimer's

... change the way the medical community thinks about molecular diagnostics and the markers they consider for many types of diseases." ?Chad Mirkin, Northwestern University Department of Chemistry and Institute for Nanotechnology "It's a good bet that the very earliest stage of AD memory loss begins when ADDLs a...

Insight into natural cholesterol control suggests novel cholesterol-lowering therapy

...its internal synthesis, he explained. However, the molecular mechanisms by which cholesterol and other related compounds exert that self-control have only more recently begun to emerge. The researchers now demonstrate that lanosterol--an intermediate compound in the synthetic pathway--mediates feedback contro...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...tion, researchers remain uncertain about the exact molecular details of infection. Earlier studies identified many "strains" of disease prions across mammalian and yeast species. Researchers thought these strains could be defined by differences in the underlying amino acid sequences of the prions. Under this ...

Stopping smallpox in its tracks: A new anti-viral approach

...ical School propose a new antiviral therapy ?a low molecular weight inhibitor of signaling mediated by the smallpox growth factor (SPGF). SPGF targets the erbB-1 signaling molecule, which normally initiates an intracellular cascade that facilitates viral replication. This study shows that drugs that interfer...

Gene Therapy Cures Inherited Liver Disease In Rats

...mal," said Dr. Brendan Lee, associate professor of molecular and human genetics and a Howard Hughes Medical Investigator at Baylor College of Medicine. Crigler-Najjar syndrome is currently treated by placing the person under special UV lights. It is an unwieldy and time-consuming treatment. While Lee does no...

Researchers identify protein crucial for survival of Lyme-disease bacterium

... can't infect animals or humans." UT Southwestern molecular microbiology graduate student Andrew Revel, a lead author of the study, found the bptA gene by screening a number of candidate genes he thought might be affecting the survivability of Bb within its hosts. The research team had hypothesized that the e...

Light therapy may combat fungal infections, new evidence suggests

...r Joseph Heitman, M.D., James B. Duke professor of molecular genetics and microbiology and medicine at Duke. Light therapy is now used for medical conditions, such as seasonal affective disorder. The most common method, called bright-light therapy, requires that patients sit near a special light box fitted wi...

Computational Method Speeds Mapping of Cell Signaling Networks

...activated T-cells to multiply rapidly and send out molecular "distress signals" that attract other immune syste...o prior knowledge of signaling pathways to uncover molecular relationships. This is a distinct advantage according to Pe'er, who notes, "Unlike classical biochem...

Glow-in-the-dark zebrafish at UH hold keys to biological clocks

...rate circadian rhythmicity, photoreceptor cell and molecular biology, and neurobiology. He is a member of the Society for Research on Biological Rhythms and the Society for Neuroscience and is currently funded under a $1.2 million National Institutes of Health grant through 2007 as the principal investigator o...

New lab technique identifies high levels of pathogens in therapy pool

...he researchers said. The two-year study involved a molecular survey of a common RNA gene found in all life form...04 study by Pace and his colleagues using the same molecular technique found that billions of microbes, in the form of "soap scum," can be found in a one-inch-sq...

Researchers rein in regulatory RNAs

... Arabidopsis SAT pairs and demonstrated that these molecular characteristics were largely conserved in plants. "Conventional belief in molecular biology suggests that poly(A)+ mRNAs are major mediators in flows of genetic information," Abe expla...

Buying Time Through Hibernation on Demand

... these chemicals are very similar to oxygen at the molecular level and so bind to many of the same receptor sites. As a result, they compete for and interfere with the body's ability to use oxygen for energy production - a process within the cell's power-generating machinery called oxidative phosphorylation. T...

U-M team recovers ancient whale in Egyptian desert

... these chemicals are very similar to oxygen at the molecular level and so bind to many of the same receptor sites. As a result, they compete for and interfere with the body's ability to use oxygen for energy production - a process within the cell's power-generating machinery called oxidative phosphorylation. T...

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