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Tag: "molecular" at biology news

DNA constraints control structure of attached macromolecules

...mical trigger is used. Like a switch, a particular molecular shape could be turned on and off. "Another key as...raints on one molecule, we could generate multiple molecular states that would be programmable by DNA sequence. In other efforts, we would like to control macros...

High fidelity keeps human DNA assembly line humming

...n living systems and cutting-edge biochemistry and molecular biology with a system of checks and balances. "RN...said Zachary Burton, professor of biochemistry and molecular biology. "If you want to understand and control things like viral infections and tumors this fundame...

UN successfully tests 'green' pesticide against locusts

...mical trigger is used. Like a switch, a particular molecular shape could be turned on and off. "Another key as...raints on one molecule, we could generate multiple molecular states that would be programmable by DNA sequence. In other efforts, we would like to control macros...

Health costs soar as 60 million Americans classed as obese

...mical trigger is used. Like a switch, a particular molecular shape could be turned on and off. "Another key as...raints on one molecule, we could generate multiple molecular states that would be programmable by DNA sequence. In other efforts, we would like to control macros...

New understanding of cell movement may yield ways to brake cancer's spread

... the right direction. Guided by this fragment, the molecular machinery needed for cell movement begins accumula...hree-dimensional picture of PIP3 -binding domain's molecular structure. "We are currently planning these structure studies with our collaborators here at the Bur...

Researchers discover key gene involved in bark beetle pheromone production

...Blomquist, professor and chair of biochemistry and molecular biology, who co-authored with several members of his department an article that will be published this week(June 27 ?July 1) in the Proceedings of the National Academy of Sciences (PNAS). Bark beetles plague pine forests, especially when the trees a...

U of T researchers map role of Epstein-Barr virus in cancer

...chers at the University of Toronto have mapped the molecular details that show how a viral protein coded in the...n of this protein complex so scientists can see in molecular detail how the EBNA1 protein binds to USP7 and the resulting impact on cell growth. Once that level ...

Ancient DNA helps clarify the origins of two extinct New World horse species

...eography of Pleistocene horses in the new world: A molecular perspective. PLoS Biol 3(8): e241. ...

Cancer related gene p53 not regulated as indicated by previous tissue culture research

The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, as it is in over half of all human cancers, checks and balances on cell growth fail to operate, and body cells star...

Critical step traced in anthrax infection

... by R. John Collier, professor of microbiology and molecular genetics at HMS, provides insight into the broader question of how proteins cross cell membranes. The findings appear in the July 29 issue of Science. An anthrax bacterium secretes three nontoxic proteins that assemble into a toxic complex on the su...

Team Invents Device For Weighing Individual Molecules

...olecules. This technology may lead to new forms of molecular identification that are cheaper and faster than ex...is opened to expose the nanodevice to an atomic or molecular beam, in this case a very fine "spray" of xenon atoms or nitrogen molecules. Because the nanodevice ...

Malaria mechanism revealed

By determining the molecular structure of a protein that enables malaria parasi...t of therapies to control malaria. To explore the molecular basis of the binding of EBA-175 to glycophorin A--with the rationale that such information might rev...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...ity -- focus on aspects of the type-III pathway, a molecular syringe that Yersinia pestis, the bacterium that may have killed more people throughout history than any other infectious disease, uses to disable its host's immune system. "Yersinia pestis is the nastiest thing alive," said study author Olaf Schnee...

Immune system's distress signal tells bacteria when to strike back

...ntly numerous, they produce two virulence factors, molecular weapons known as PA-I and Pyocyanin. PA-I causes the barrier cells that line the host's bowel to become more permeable, which renders them more susceptible to the microbe's toxins. Pyocyanin enhances the germ's ability to pass through the weakened bo...

Protein synthesis can be controlled by light, opening way for new scientific, medical applications

...nding the mechanisms of learning and memory at the molecular and cellular level," said Dore. The technique could also be used in drug discovery and development, though it is much more likely to be used in advancing knowledge about biological systems. ...

Random gene expression may drive HIV into hiding

...come latent in some cells by harnessing the random molecular behavior of the cell. HIV can hide in cells for y...tain cell. "Most of the other groups studying the molecular mechanisms of HIV latency were coming at it from a deterministic point of view based on the belief t...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

...d is a tailored therapy for tumors with a specific molecular signature." Resurrecting tricirbine may be promis...Sebti says, "The beauty of this trial is that it's molecular therapy, based on the blueprint of the tumor cell." ...

The making and breaking of microtubules

... For the first time, researchers have revealed at molecular level the forms taken by transitional structures o...vision, an associate professor of biochemistry and molecular biology at the University of California at Berkeley, and a Howard Hughes Medical Institute Investiga...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...ong with colleagues David Ann, Ph.D., professor of molecular pharmacology and toxicology, and Yun Bai, doctoral student in the Department of Pharmaceutical Sciences, wrote a paper on this research that will appear in the May 17 issue of the Proceedings of the National Academy of Sciences (PNAS), which is curre...

UI researcher studies deafness in fruit flies, humans

... antenna. Eberl's research shows that at least one molecular component specialized for hearing function, myosin...ng are very effective tools for learning about the molecular and cellular mechanisms involved in hearing in insects and animals, including humans, says Eberl, wh...

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