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Tag: "molecular" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...imic naturally occurring enzymes, which facilitate molecular synthesis and transport within the body. Over the ...en top, much like an open-air stadium. Its general molecular formula is C268H320O52. The tiny molecules can be modified to include other functional groups that g...

Man and mouse share genome structures

...ucture in leukemic cells and gain insight into the molecular basis of disease. "The human genome still has many surprises lurking within it," said Lander, director of the Broad Institute and senior author on the study. "One of the most important is the mystery of how genes are turned on. The ability to take g...

Molecular biology fills gaps in knowledge of bat evolution

...the Jan. 28 issue of the journal Science that uses molecular biology and the fossil data to fill in many of the...test research is significant because it shows that molecular information can contribute to resolving and illuminating long-standing problems in evolutionary biol...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...ber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the firs...ynthesis of triglycerides and cholesterol, but the molecular chain of events from eating fats to the buildup of cholesterol and triglycerides in the blood were u...

A new mechanism of regulating RNA degradation

...l component of the NMD complex, Upf1, as bait in a molecular fishing expedition. With this approach, proteins that naturally interact with the bait will be pulled out of the pool of cellular proteins. They found that Upf1 grabbed onto Staufen1 (Stau1). Stau1 is a well-known RNA binding protein and some of its...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...l component of the NMD complex, Upf1, as bait in a molecular fishing expedition. With this approach, proteins that naturally interact with the bait will be pulled out of the pool of cellular proteins. They found that Upf1 grabbed onto Staufen1 (Stau1). Stau1 is a well-known RNA binding protein and some of its...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...ase SLE, and maybe otherautoimmune diseases at the molecular level," says Professor LarsRönnblom. "Itis remark...er functionalanalyses will be necessary to map the molecular mechanisms in detail.Besides the Rheumatology Clinic at Uppsala Akademiska Hospital,hospitals in Ume...

Source of molecular triggers in cutaneous T cell lymphoma identified

...in the journal Blood, Yale scientists identify the molecular triggers that stimulate Cutaneous T Cell Lymphoma (CTCL) cells to clonally expand into large populations of malignant lymphocytes. CTCL is the most common adult malignancy of T lymphocytes, the white blood cells of the immune system. Finding CTCL tr...

Protein discovery could unlock the secret to better TB treatment

...ntibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to des...exist in TB bacteria. The paper's unveiling of the molecular structure of Rpf could be crucial to the treatment of TB in the future. Dr John Ward, Dept of Bioch...

W.M. Keck Foundation funds study of friendly microbes

...atabase will be established that provides detailed molecular information about the gut ecosystem for researchers. A second aspect of the project aims to directly identify the products of bacterial metabolism in the intestine. The goal is to characterize previously unknown chemical compounds that play importan...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

... Norman Pace, one ofthe world's leading experts on molecular evolution and microbiology,published their report "Hydrogen and bioenergetics in the Yellowstonegeothermal system" this week in the online edition of the Proceedingsof the National Academy of Sciences.The team's findings, based on several years of re...

Fox Chase Cancer Center scientists identify immune-system mutation

... attracted to class I MHC. However, the underlying molecular pathways that regulate this process have remained obscure. "The mutant HD mice are unable to generate mature helper T cells, even though their immature T cells carry the CD4 protein," Kappes explained. "Instead, the mutation redirects them to the ki...

Controversial drug shown to act on brain protein to cut alcohol use

...en GDNFand reversal of addiction -- knowledge of a molecular mechanism thatshould allow development of a new class of drugs to treat addictionwithout Ibogaine's side effects," said Dorit Ron, PhD, UCSF associateprofessor of neurology and also principal investigator at the GalloCenter. Ron is co-senior author o...

Neuronal 'traffic jam' marks early Alzheimer's disease

...hat might be used to develop drugs to preserve the molecular transport system and thus the viability of brain c...transport protein, kinesin-1, the cell's principal molecular motor for transporting proteins. "We made a modest reduction in the level of a motor protein called ...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...M.D.,UCSD professor of medicine and cellular & molecular medicine, andco-director of the UCSD Glycobiology ...em cells has become morespecific, being defined in molecular terms," Varki said."Such issues will, of course, become irrelevant if complete eliminationof Neu5Gc ...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...tiation until the time is right. Understanding the molecular control of these genes has implications for therap...e regeneration. A fundamental understanding of the molecular programs that regulate stem-cell differentiation is necessary for harnessing this potential. ### T...

Timing is everything: First step in protein building revealed

...e quitesimilar. "Theidea is to really know at the molecular level how life is puttogether," says Jon Lorsch, Ph.D., professor of biophysics andbiophysical chemistry, one of the departments in Johns Hopkins'Institute for Basic Biomedical Sciences. "We see disease largely as anincorrect timing event -- the wron...

Plants, animals share molecular growth mechanisms

... specific function of certain actin filaments. The molecular tools Szymanski's research team developed will help scientists learn more about these functions in both plants and animals. The other researchers on this study were Dipanwita Basu and Salah El-Din El-Essal, research assistants; postdoctoral students...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...ic lymphocytic leukemia require revision. With new molecular and protein markers now identified, patients with features that portend poor outcomes may soon be treated earlier and more effectively," said Dr. Chiorazzi. "Once these new prognostic markers are clinically available to doctors, and after large-scal...

Research advances quest for HIV-1 vaccine

...alifornia performed a study examining the detailed molecular structure of the complex formed when 4E10 binds to...derstanding broadly neutralizing antibodies at the molecular level and transferring this knowledge into the design of vaccines capable of stimulating broadly neu...

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