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Tag: "modified" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

... formula is C268H320O52. The tiny molecules can be modified to include other functional groups that give it additional properties, Sherburn says. For instance, one highly active version of the superbowl molecule goes by the name tetrabromo-superbowl (C268H320O52Br4) due to the addition of four bromine atoms....

Researchers discover way to make cells in the eye sensitive to light

...light-induced pupillary constriction ingenetically modified mice that lacked melanopsin. When the mice lackingmelanopsin were exposed to low light, their pupillary response was thesame as normal mice, but when they were exposed to bright light theirpupil constriction was incomplete.The researchers believe tha...

Plants respond similarly to signals from friends, enemies

...m other organisms ?certain genes in the plant were modified to accomplish this ?they discovered that the plants failed to respond to signals from both friend and foe, and therefore no changes were viewed in the plant's cytoskeleton. "This exquisite system that plants have developed to allow beneficial intera...

Live Recombinant Adenovirus Vaccine Technique Explored

...cines for a variety of illnesses using genetically modified adenoviruses, a common cause of respiratory infections. Oral adenovirus vaccines have long been proven to be safe and effective. The researchers believe their process for constructing a replicating live recombinant adenovirus could lead to more econo...

Mitochondrial DNA mutations play significant role in prostate cancer

...hout the disease mutation. They theninjected these modified prostate cancer cells into mice to assess theirtumor-forming ability. The prostate cancer cells with the mutant mtDNAsgenerated tumors that were on average seven times larger than theprostate cancer cells with normal mitochondria. Hence, the deleteri...

Gene therapy converts dead bone graft to new, living tissue

...ere barely expressed around the dead bone. He then modified a harmless virus to carry these genes, devised a m...d bone when Schwarz paints it with the genetically modified virus. New blood vessels begin to grow around and into the bone splint, stripping it down in times w...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

... gene is delivered to patient cells, often using a modified virus. Gene therapy might offer an alternative treatment for those children who fail to respond to enzyme replacement therapy, he said. Even for those that respond well to enzyme infusions, treatment requires weekly injection of a large amount of th...

BRCA1 causes ovarian cancer through indirect, biochemical route

... by looking at ovarian cancer rates in genetically modified mice created in collaboration with Robert Maxson, Keck School professor of biochemistry and molecular biology and director of the mouse core facility at the USC/Norris Cancer Center. "The whole project was based on creating a mouse that lacks BRCA1 i...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

... Pneumococcusvaccines for children must instead be modified by binding thosecarbohydrates to special proteins that stimulate the immune systems ofyoung children. “However such vaccines are so complex that they cancarry carbohydrate targets for only a few specific strains of pneumoniabacteria,?Tuomanen said. “...

New comparative toxicogenomics database

... Pneumococcusvaccines for children must instead be modified by binding thosecarbohydrates to special proteins that stimulate the immune systems ofyoung children. “However such vaccines are so complex that they cancarry carbohydrate targets for only a few specific strains of pneumoniabacteria,?Tuomanen said. “...

Genetically modified natural killer immune cells attack, kill leukemia cells

...killer (NK) immune system cells can be genetically modified to brandish a powerful "on-switch" that prompts th...kemia cell called K562. Campana's team genetically modified the K562 cells so they carried on their surfaces many copies of two different proteins, 4-1BBL and I...

Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra

...Byrd said. "The terrestrial ecosystem was probably modified in more ways than we know, and maybe it won't be exactly like it was, but the conditions are there for a successful restoration of the native biodiversity." ...

UCLA scientists transform HIV into cancer-seeking missile

...er cells. The UCLA team is the first to prove that modified HIV will target and bind with P-glycoproteins. "P-glycoproteins cause big problems by making the cell resistant to chemotherapy," said Chen. "They act like soccer goalies and punt therapeutic drugs out of the cancer cell. This prevents the drug from...

Influenza vaccine uses insect cells to speed development

Using a strategy involving a genetically modified baculovirus and caterpillar cells scientists from Protein Sciences Corporation have been able to speed up a key step in the development of an experimental cell-based influenza vaccine. They report their findings today at the 2005 American Society for...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

... exactly what we saw in mice that were genetically modified so their B lymphocytes were over-expressing MYC," Grosveld said. "When we forced over-expression of TEL2 in these mice, we curtailed apoptosis in the precancerous B lymphocytes that were being forced to multiply by MYC." But even the combined effect...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

... Rush. Pollack says the current protocol has been modified to reduce the likelihood of inadvertant scientific bias. "We operated on the right eye of each of the initial 10 patients. For the next 20 patients we will randomly select which eye will receive the ASR chip. In addition, post-operative vision tester...

Children's taste sensitivity and food choices influenced by taste gene

...ces on bitter taste sensitivity were in some cases modified by age. In individuals with the mixed AP genotype, children were more sensitive to bitter than adults, with 64% of children but only 43% of adults able to detect bitterness in the weakest PROP solution. "This type of information will one day help to...

Ophthalmologists implant five patients with artificial silicon retina microchip

... Rush. Pollack says the current protocol has been modified to reduce the likelihood of inadvertant scientific bias. "We operated on the right eye of each of the initial 10 patients. For the next 20 patients we will randomly select which eye will receive the ASR chip. In addition, post-operative vision tester...

Genetically modified rice in China benefits farmers' health, study finds

Farmers growing genetically modified rice in field trials in China report higher crop y...rmers." China began doing research on genetically modified agricultural crops in the 1980s. Although it has aggressively commercialized "Bt cotton," geneticall...

Drug-resistant bacteria on poultry products differ by brand

...ng both standard isolation methods and new methods modified to enhance detection of fluoroquinolone-resistant Campylobacter, they compared retail products purchased at grocery stores in Baltimore, Md. A high percentage of the products from the two conventional brands were contaminated with fluoroquinolone-res...

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