models 2 7

Tag: "models" at biology news

Better sludge through metagenomics

... communities with the goal of designing predictive models to understand how these communities function," said Hector Garcia Martin, lead author of the study and post-doctoral fellow in the DOE JGI's Microbial Ecology Program. "With this information now available, there are opportunities to bioengineer the p...

Cell wall of pneumonia bacteria can cause brain and heart damage

...ldren's Research Hospital have discovered in mouse models how cell walls from certain pneumonia-causing bacteria can cause fatal heart damage; researchers have also shown how antibiotic therapy can contribute to this damage by increasing the number of cell wall pieces shed by dying bacteria. The team also d...

Save the whales? Sure, but how many?

...shing) or non-consumptively (as in tourism.) Most models for sustainable use only conserve animals at the level of demographics, not ecology, Sanderson says. The highest standard for animal populations is achieving 'historical baselines' where species are restored to when humanity as a whole had signific...

Key gene controlling eye lens development identified

...ldren's Research Hospital have discovered in mouse models that a gene called Six3 is one of the earliest critical regulators controlling lens development in the eye of the mammalian embryo. Mutations in Six3 have been previously identified in patients with holoprosencephaly, a disease that can cause the p...

Striking the right balance between excitation and inhibition

...oup are likely to be important for devising animal models to study these pain pathways. ...

Rhesus monkeys in Nepal may provide new alternative for HIV/AIDS research

... and represent one of the most widely used primate models for AIDS-related research. India, however, banned the export of all macaques in 1978, thus leading to the current shortage. Although China has been exporting captive-bred animals for sometime, scientists have noted a number of behavioral and physio...

Test reveals effectiveness of potential Huntington's disease drugs

...e been tested in a variety of Huntington's disease models and some HD human trials and results are very difficult to interpret," said Dr. Ilya Bezprozvanny, associate professor of physiology and senior author of the study, available online and published in today's issue of Neuroscience Letters. "For some of...

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer

...have shown in the laboratory and in several animal models that measles virus strains can significantly shrink glioma tumors and prolong animal survival. It is very rewarding to see this work maturing to the point of now being able to offer this novel and promising treatment approach to patients with recurr...

Common carp sheds new light on surviving in extreme environments

...c its effects. "This work shows how exotic animal models can give vital information on how living systems work. The carp is an unusual animal because it routinely copes with very challenging conditions that would harm or even kill lesser creatures. This is because the fish has evolved in small-to-medium ...

New angiogenesis finding may help fight cancer growth

...how the molecule works in human cells and in mouse models of angiogenesis. Eventually, after years of basic research and drug development, the multitalented compound NK-B could wind up playing a major role in treating cancer and other diseases where blood vessel formation goes awry, Bresnick says. "We ...

New strategy developed to combat West Nile Virus

...enters for Disease Control. Many early hydrologic models predicting the transmission of West Nile Virus and...nalyze different regions of the country and create models similar to that of southern Florida, where certain weather patterns set off the chain of events that...

Study provides first look at the 'birth' of a retina cell

...is new mouse model in conjunction with other mouse models of specific diseases, such as macular and other re...tions. Gene profiling of rods and cones in disease models at various stages of pathogenesis could help scientists identify molecular targets for drug treatmen...

Robots manipulating animal behaviour

...earchers collected data and developed mathematical models describing the collective behaviour of sheep, such as clustering together in a field. These models have yet to be taken up in a follow-on project, but are scientifically valuable. Adds Deneubourg, "T...

'Molecular assassin' targets disease gene

...ion. It details tests in a variety of pre-clinical models showing how effective Dz13 is in problems such as eye disease and arthritis. The next phase in the therapy's development would be a trial, involving up to 10 people with non-melanoma skin cancers. The tumours would be injected with the drug over an ...

A new view on Lyme disease: Rodents hold the key to annual risk

...From this 13-year dataset, they developed computer models to estimate how each of the 11 variables (includin...r temperatures keep tick populations down, but the models showed them increasing both total density and density of infected nymphs. And though tick survival i...

OHSU study says stem cell 'fusion' occurs in tumors

...k of cancer. This balance can be examined in mouse models of inflammatory bowel disease, where, like humans, epithelial damage and chronic tissue repair occurs. "Ten percent of patients with inflammatory bowel disease go on to get colorectal cancer," Wong said. "We think that the bone marrow cells aid in r...

NYU algorithm enhances ability to detect cancer genes

...high resolution of gene-chips and prior biological models through Bayesian statistics in order to optimally pinpoint the genes involved in the cancer, even when these genomes may have many other unrelated deletions, which happen as "collateral damage" to the genomes as the cancer progresses to an advanced s...

The higher the hierarchy, the greater the aggression

... The researchers developed two simple mathematical models that predicted that, if inheritance rank mattered in a cooperative society, then the rates of aggression would be highest toward the front of the queue and that the aggression would increase as the time available to inherit the ability to breed ran o...

Drug dials down the energy within cells, UM researchers find

A drug effective at treating animal models of human autoimmune disorders and other diseases works by dialing down the activity of a key enzyme involved in energy production, University of Michigan researchers have found. "Many drugs block the function of enzymes, essentially turning them off...

The Midas Bug -- the bacterial alchemy of gold

...e for the mineral exploration industry ?as current models of gold formation do not include a biological mechanism. "There may be new opportunities for the bio-processing of gold ores now that we have discovered bacteria that precipitants gold out of solution," Dr Reith said. ...

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