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Tag: "models" at biology news

Inhibiting blood to save the brain

...hibits this specific inflammation process in mouse models of MS, reducing MS symptoms. "Current strategies to develop therapies to fight MS primarily target T cells," said Katerina Akassoglou, Ph.D., assistant professor in UCSD's Department of Pharmacology, whose study was published in the March 19 issue ...

Pregnancy hormone key to repairing nerve cell damage

... study. Subsequent tests of prolactin in animal models of MS will be required before testing of prolactin on humans can take place, but MS researchers are hopeful human trials can take place within the next several years. "This discovery has the potential to take MS therapy a step further than current...

Circumcision: A proven strategy to prevent HIV

...ntion of new infections is crucial." Simulation models estimate that millions of new HIV infections, tens of thousands of deaths, and several million dollars could be saved if male circumcision became routine in sub-Saharan Africa. "This is really the first good news we've had in quite a long time. If...

Ocean's 'twilight zone' may be a key to understanding climate change

...ay to improve the predictive capacity of numerical models that relate ocean carbon to global climate change on different time scales," said Don Rice, director of NSF's chemical oceanography program. It also adds a new wrinkle to proposals to mitigate climate change by fertilizing the oceans with iron--t...

Satellites shed light on global warming

...the effect of waves in models, helping to make the models more realistic, which means better predictions for...ng and improves the accuracy of our climate change models and weather forecasts. "There is now evidence there is a distinctive upward trend in global sea ...

Turning a cellular sentinel into a cancer killer

...although there are differences between these mouse models and human cancers—we now can say with some confidence that established tumors are sensitive to p53 reactivation. There are already a number of treatment strategies being tested to restore p53 function, and these might well be expected to have therape...

Nanoparticles for delivery of prostate cancer treatment

...delivery packets ?to deliver the therapy in animal models of human metastatic prostate cancer. "While we...ne, a system that was effective and safe in animal models and is being prepared for a clinical trial. "The advantage of nanoparticle vectors is that they ...

'Hidden-hero' microbes in soil, water may help naturally clean toxic sites

...he country. Together, the partners will develop models to help predict the rate at which contamination levels drop when using natural methods such as bioremediation and artificial techniques such as chemical additions and pH adjustments. Subsurface changes are monitored using geophysical methods that sen...

Stem cell therapy shows promise for rescuing deteriorating vision

...xperimentally to deliver the same growth factor in models of Parkinson's disease and Lou Gehrig's disease. Svendsen is also an author of the new PloS One report. "It seems that the cells in and of themselves are quite neuroprotective," says Gamm. "They don't become retinal cells. They maintain their own ...

MIT's ocean model precisely mimics microbes' life cycles

...rinciples of natural selection. Scientists use models such as this one to better understand the oceans' .... Chisholm believes that because previous ocean models did not convey the diversity of phytoplankton, they did not well represent the systems they modeled....

Biologists call for better choice of model organisms in 'evo-devo'

...as not yet been optimised. Dr Wills said: "Many models to date, in particular the big six, have been chos...s of 35 phyla of animals, and four of our six best models come from just one phylum. "However, that doesn’t mean that simply choosing new models to plug h...

Does evolution select for faster evolvers?

...e of Physical Review Letters. Past mathematical models of evolution have focused largely on how populatio...l dynamics of evolution. In comparison to existing models that account for only point mutations or sexual recombination, Deem and Park's model shows how HGT i...

New imaging technique tracks traffic patterns of white blood cells

...crodomains." Researchers explored various mouse models including that of Sickle Cell disease which is a common inherited blood disorder in the United States, affecting 72,000 Americans according to the National Institutes of Health (NIH). Sickle Cell disease is a blood disorder that affects hemoglobin, a...

Virginia Tech's System X supercomputer provides super tool for simulation of cell division

...he university's supercomputer, System X, to create models and algorithms that make it possible to simulate t.... They have demonstrated that the new mathematical models and numerical algorithms provide powerful tools for studying the complex processes going on inside l...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...ainst Huntington's disease in two different animal models (worms and mice). "The "healthspan" benefits we saw in the obese mice treated with resveratrol, such as increased insulin sensitivity, decreased glucose levels, healthier heart and liver tissues, are positive clinical indicators and may mean we can...

Low levels of neurotransmitter serotonin may perpetuate child abuse across generations

... in primates. Other research using rats as animal models has shown that serotonin production is influenced by a mother's treatment of her offspring early in their lives and affects the offsprings's responses to stress in adulthood. In earlier research on abuse of infant monkeys, Maestripieri and his col...

By 2048 all current fish, seafood species projected to collapse

...rend, and it is accelerating. We don't have to use models to understand this trend; it is based on all the available data." Researchers also determined that the problem is much greater than losing a key source of food. Damage to the oceans impact not only fisheries, but the ocean ecosystem's overall produ...

Proteins may predict lung transplant rejection

... Wendt explained. Her team has developed two mouse models to determine whether these proteins play a role in the development of chronic lung rejection or whether they are a byproduct of the disease. ...

One-of-a-kind imaging probe reveals secrets useful for drug discovery

...ted in using the new probe. "For example, in mouse models of Parkinson's or Alzheimer's disease, there is not a lot of tissue to work with, especially if you're studying a sample from a single animal. But this is a way we could obtain potentially important chemical information about disease from small amoun...

Salmon farms kill wild fish, study shows

...00 fish," said Krkosek. "We then used mathematical models to combine this information and estimate the total impact of the farms." "The work is of an impeccably high standard, and will be very difficult to refute," said Dr. Andy Dobson, an epidemiologist from Princeton University who specializes in wildli...

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