TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
...Grosveld's team found that this sequence of events modeled in the mouse also occurs in human lymphoma patients. Combined elevated TEL2 and MYC expression occurred in the B lymphocytes of over a third of patients with a B lymphoma called B-acute lymphoblastic leukemia. "These results offer new hope for impro...Supercomputer Dedicated To Bioengineering, Computational Biology Installed
...ll nodes, bioengineering researchers this week had modeled how electrical impulses trigger contractions in the heart of a pig. ...Physiological effects of reduced gravity on bacteria
...tra-specific differences in bacterial responses to modeled reduced gravity" by Paul W. Baker and Laura G. Lef...e strains of the same species. Reduced gravity was modeled using clinorotation. The findings suggest that conditions on the ISS might have favoured bacteria th...Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
...e for all practical purposes wiggles that are best modeled by traditional statistical approaches. "The dynamics are the same during warm and cold periods, thus they are not true regimes," said Sugihara of the Physical Oceanography Research Division at Scripps. This is at least true for these data from the 20...Storing carbon to combat global warming may cause other environmental problems, study suggests
...ral, "unlike in the tropics, the temperate regions modeled here did not have sufficient energy to lift the additional atmospheric moisture high enough to condense and form clouds," the study said. "Plantations not only have greater water demands than grasslands, shrublands or croplands," the study added. "T...Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates
...e not targeted. This prostate cancer targeting was modeled using a microfluidic device and shown to occur under physiological fluid flow conditions that are present in systemic microvasculature, making their use after intravenous administration therapeutically relevant. The investigators also used high magni...Researchers use 'trickery' to create immune response against melanoma
...e not targeted. This prostate cancer targeting was modeled using a microfluidic device and shown to occur under physiological fluid flow conditions that are present in systemic microvasculature, making their use after intravenous administration therapeutically relevant. The investigators also used high magni...Study shows AIDS drugs cost-effective, care underfunded
...nfected patients, researchers previously relied on modeled estimates of health care expenditures. Now, using actual healthcare utilization data, researchers at the University of Alabama at Birmingham (UAB) have analyzed a year's worth of total health care expenditures for 635 HIV-infected patients, including...Gene therapy injected into the brains' of mice with Huntington's disease
... were involved in the 4 month study. All mice were modeled to have the genetics of HD. The HD mice exhibited...GDNF's exact role in preventing cell death in mice modeled with HD remains to be established, we speculate the increase trophic support and inhibiting apoptosi...RNA found in the cellular centrosome of surf clams
...s and their eggs as research models. Clam eggs are modeled as simple versions of human cells, and biologists who study cell division value them for several reasons, according to Palazzo. The eggs develop fast, entering the process of cell division less than 15 minutes after fertilization, and, once fertilize...Trotting with emus to walk with dinosaurs
...accuracy photos to be taken. These can be computer modeled and even made into physical prototypes with rapid prototyping technology. The bigger picture is also important and telling at the Red Gulch Dinosaur Tracksite, said Breitaupt. For instance, it appears that the dinosaurs were traveling along a tid...On the golf tee or pitcher's mound, brain dooms motion to inconsistency
...kinds of computing by building artificial circuits modeled on the brain. But Shenoy says the research simply set out to explain variability in movement. "This is basic science," Shenoy says. "We ask questions because we want to know." The study could help resolve a question about human nature, however. W...Pilot study successful in taming allergic reactions to food
...rance to those items. Burks and his colleagues modeled the study on a commonly used method for treating seasonal allergy sufferers to alleviate symptoms. In this approach, called immunotherapy, physicians give patients shots containing small amounts of the troublesome allergen in an effort to build their......stories of colorectal cancer. Turning to mice that modeled the loss of IGF2 imprinting, Feinberg found an increase in frequency of tumors in mice who also had mutations in a cancer-associated gene called Apc. In the mutant Apc mice, the loss of IGF2 imprinting seems to particularly affect the behavior of the...MIT model helps researchers 'see' brain development
...f smaller, higher-resolution folds. Finally, Yu modeled biological growth using a technique recommended by Grant that allowed her to identify the age at which each type of fold, coarse or fine, developed, and how quickly. She found that the coarse folds, equivalent to the largest folds in a crumpled pi...US control strategies may make flu epidemics worse, UCLA study shows
...they think are other people's decisions. The group modeled each individual's strategy for making yearly vaccination decisions as an adaptive process of trial and error. They tracked both individual-level decisions and population-level variables ?that is, the yearly vaccine coverage level and influenza preval......s at the University of Illinois have painstakingly modeled a critical part of a mechanism by which bacteria take up large molecules. Their findings provide a rare window on the complex interplay of proteins involved in the active transport of materials across cell membranes. Their study, which includes a co...