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Tag: "model" at biology news

A molecule impedes the destruction of the 'Brucella' bacteria

...ure Immunology scientific magazine. Brucella is a model of an intracellular parasite, a category that includes other important bacteria, such as those of tuberculosis or legionelosis. Brucella penetrates the macrophages within membranous vesicles that are not fused with lysosomes (structures containing ce...

Gambling monkeys give insight into neural machinery of risk

... Confident that they had developed a valid animal model that would reveal insights into the brain mechanism for assessing risk, the researchers next explored the neural circuitry that governed that assessment. They threaded hair-thin microelectrodes into a brain region called the posterior cingulate corte...

UNC computer, marine scientists collaborate to predict flow of toxic waters from Katrina

...e-dimensional computer program that can be used to model water levels and flow. This program, "ADCIRC," is ...n Mesoscale Model, the primary weather forecasting model used by the National Weather Service, to simulate wind speed, direction and other weather factors. T...

Slipping past the blood brain barrier: Research shows potential treatment for brain cancer

...es when there's a big difference between an animal model and the human condition. In terms of getting drugs across the blood brain barrier to fight cancer, there's not such a big difference. There's pretty much the same rules in any blood brain barrier - be it in a mouse or human." Laura Jaeger, the lead ...

Temperature regulates circadian clock in zebrafish

...r level in zebrafish. This genetically tractable model organism is especially suited to this task because adults, larvae, and even embryos can tolerate a wide range of core body temperatures (being cold-blooded animals) that can be manipulated simply by changing the water temperature. Temperature variati...

Beyond genes: Lipid helps cell wall protein fold into proper shape

...the presence of PE. The team is using the E. coli model to discover how all proteins fold in the membrane, not just transport proteins such as GabP but also biosynthetic proteins that manufacture complex compounds such as proteins and fats out of simple compounds. "The next goal now that we've defined th...

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

... monkeys can provide a critically important animal model of how the brain controls what humans pay attention to in social situations. Such a model would enable scientists to better understand how processing of social attention works in the brain, ...

Drug resistance testing in treatment-naive HIV patients is cost-effective

... beginning of the epidemic," said Dr. Sax. Using a model with a resistance rate of just over 8 percent, the analysis estimated a cost of $23,900 per quality-adjusted life year gained, which is within the range of other commonly accepted HIV interventions. The cost-effectiveness calculation remained below $...

Study shows eutrophic lakes may not recover for a millennium

...nd aquatic ecosystems into overdrive. Carpenter's model also shows that, unchecked, phosphorus pollution could put Lake Mendota on a fast track to extreme degradation. "There is a potential shift to an extremely degraded state that could occur even if we shut off the phosphorus tomorrow. It would have wat...

Engineered skin offers clues to melanoma development

...thor Adams. The team plans to use the human-tissue model of melanoma to evaluate potential treatments. ...

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

...thor Adams. The team plans to use the human-tissue model of melanoma to evaluate potential treatments. ...

U of MN researchers reverse memory loss in mice

...mentia as previously thought. The mice serve as a model that shows how the disease progresses as well as the possibility that memory loss can be reversed. The research suggests that the same reversal may be possible in humans, and that people with Alzheimer's disease may be able to recover memory and impr...

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

...thor Adams. The team plans to use the human-tissue model of melanoma to evaluate potential treatments. ...

The synapse is a shotgun

...s transformed their map into a functional computer model by incorporating the physiological details of neur... The researchers then compared the behavior of the model under different scenarios with the electrophysiological behavior of actual ganglia measured in Berg'...

Defect in gene causes 'neuralgic amyotrophy'

...vous system disorders. Therefore, HNA is a genetic model for more frequently occurring disorders such as the Parsonage-Turner Syndrome and neurological disorders like Guillain-Barr?Syndrome. Genetic cause of HNA discovered VIB researchers in Antwerp, under the direction of Vincent Timmerman and Peter...

Rensselaer researchers develop approach that predicts protein separation behavior

... of small drug-like molecules. The newly developed model successfully predicted the amount of a protein tha...case, particular proteins. "We intend to test the model against more complicated protein structures as part of its further development," said Breneman. "The...

How cell suicide protects plants from infection

...tion between plants and viruses using tobacco as a model system. They identified and silenced a "pro-survi...iences (NIGMS). "Like other studies carried out in model organisms, these findings shed light on similar processes that occur in mammals, and may eventually ...

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

...ning technique called rough sets to mathematically model general rules that could associate known binding sites and gene expression in yeast, which is one of the most widely studied organisms." From the analysis of gene activity under a variety of environmental conditions, the teams were able to develop a ...

Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development

...hair is 80,000 nanometers thick.) ASLV is a useful model for several viruses, including Ebola, the 'flu, and measles, as well as HIV. "This system is especially well suited for these types of studies because the fusion mechanism of this virus can be finely manipulated and monitored in the lab, allowing fo...

Squeezing out dune plants

...esearchers from Texas A&M University created a model to better understand the impacts of development and coastal erosion on plant communities, including plants that grow in the ever-shrinking strip of habitat between land and the ocean. Rusty Feagin, Douglas Sherman, and William Grant simulated varyin...

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