Tag: "model" at biology news

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...y represent both the cradle of life on Earth and a model for the exploration and discovery of life on other planets. "We are highly conscious of the importance of microbes in the grand scheme of things," said Haymon. "Indeed, they are the greatest biomass on the planet. They are strongly implicated as the...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...GF2 and the APC mutation should be a useful animal model to evaluate the impact of colon cancer prevention strategies, including dietary interventions and targeted drugs. ...

Fox Chase Cancer Center scientists identify immune-system mutation

...s humans. In addition to providing a unique animal model to study the SCID syndrome, SCID mice have become a highly valuable tool for studying the immune system and are now used by scientists worldwide. Kappes' co-authors on the new Nature paper include Fox Chase postdoctoral associates Xiao He, Ph.D., Xi...

Controversial drug shown to act on brain protein to cut alcohol use

...ist," Janaksaid.The scientists confirmed in a cell model that Ibogaine stimulated GDNFactivity. Finally, they showed that a known inhibitor of GDNF blockedIbogaine's ability to decrease alcohol craving in the rats, suggestinga direct link between Ibogaine's desirable actions and GDNF."If we can alter the G...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists wi...tzman and Brendza plan to continue using the mouse model to studydisease treatments and the cellular abnormalities caused by theirAlzheimer's-like condition....

Key molecule in plant photo-protection identified

Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists wi...tzman and Brendza plan to continue using the mouse model to studydisease treatments and the cellular abnormalities caused by theirAlzheimer's-like condition....

Anti-bacterial additive widespread in U.S. waterways

...use it is more easilydetectable.Using an empirical model and published data on the environmentaloccurrence of triclosan, the researchers predicted triclocarbanconcentrations for 85 U.S. streams. The study results suggest that theantimicrobial contaminant is present in 60 percent of the U.S. waterresources ...

Plants respond similarly to signals from friends, enemies

...time, the NC State researchers discovered that the model legume Lotus japonicus responded similarly to signals from both rhizobia, the friends that fix nitrogen for the plant, and root-knot nematodes, the parasitic foes that want to harm the plant. Signals from both outsiders induce rapid changes in distri...

Scientists Replicate Hepatitis C Virus in Laboratory

...se has suffered from the lack of a robust in vitro model system,?says T. Jake Liang, M.D., Chief of the Liv...anch of the NIDDK and co-author of the study. “Our model system produced viral particles that have all the properties of the whole virus. This evidence toget...

The secret to longevity in tubeworms

...s its sulfide. Without this return of sulfate, the model predicts an average lifespan of only 39 years in a...t still awaits direct confirmation. By providing a model in which this hypothetical interaction provides real benefits and explains real observations, the au...

Male circumcision reduces risk of HIV transmission from women to men

...ty of infection was calculated using a statistical model thatincorporated published data to estimate the rates of HIV infectionamong the three types of sexual partners.For the men in the study, the overall probably of becoming HIV-infectedfollowing a single act of intercourse was calculated to be .0063, or...

Computers to be used to find blueprint for new influenza drug

...s that are attacked. By using advanced software to model the way these atoms behave in highly complex interactions, the atomic structure of a suitable drug can be worked out. Using computer modelling in this way can be of great assistance in drug design. Normally drugs are produced by trial and error in a...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

...in where these neuronshave degenerated in a monkey model of Parkinson disease, can reverseparkinsonism. The...anagent called MPTP, which is considered a primate model for Parkinsondisease. These transplanted cells were able to function as DA neuronsand diminished Par...

A much-needed shot in the arm for HIV vaccine development

...sing them,and proposes an innovative collaborative model that ensures thatresearchers across the globe are ...e opportunitiestogether, and their plan provides a model for doing just that."A preventive vaccine is the world's best long-term hope for bringingthe HIV/AID...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...n healthcare the envy of the world, the commercial model only works ifcompanies can sell enough patented pr...p;Dcosts and produce profits for shareholders. The model thus fails in thedeveloping world, where few patients can afford to pay patented pricesfor drugs. Th...

Genome-wide mouse study yields link to human leukemia

...uthor of the study. "It's also validated our mouse model as a good predictor of what happens in the develop...Caligiuri, "so that gives added merit to our mouse model as an investigative tool." Using data from the methylation studies, Caligiuri and Plass were able t...

The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life

...n of eyes and the brain in embryonic fish or other model organisms. The presentation of SPIM at scientific conferences has generated a flood of requests for the instrument. "We were extremely pleased to have found Carl Zeiss as an excellent partner to translate this technology into a product," says Dr. M...

Novel Enzyme Shows Potential As An Anti-HIV Target

...y histones) and DNA. Another, more widely accepted model proposes that histone acetylation controls transcription by recruiting cofactors required for transcription. Acetylation and deacetylation enzymes can also target other proteins. Of the three classes of deacetylases known to modify human histones, t...

Live Recombinant Adenovirus Vaccine Technique Explored

...s that the replicating live recombinant adenovirus model shows promise as a means of developing economical and long-lasting vaccines for many illnesses. Ongoing research is aimed at determining the effectiveness of recombinants in animals. Additional authors of “Viable adenovirus vaccine prototypes: High-...

Researchers reveal the infectious impact of salmon farms on wild salmon

...es far beyond a theoretical model. They tested the model in the real world, using an enormous data set, and saw the same patterns. It is a very thorough analysis." "We've tried to be very careful and conservative ?but there is potential for a major impact on the survivorship of the migrating salmon," says...

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