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Tag: "mimic" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...olecules that were first developed in the 1980s to mimic naturally occurring enzymes, which facilitate molecular synthesis and transport within the body. Over the years, these bowl-shaped molecules have been extensively studied and refined by chemists for their wide range of potential uses, including drug ...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...o. Conditions below the sea floor may most closely mimic the environment when life began. "There is a great deal of interest in the microbes of the Earth's crust because the strategies by which they survive may be similar to the earliest strategies of life on Earth, and perhaps also on other planetary bod...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...IGF2; their H19 gene was intact. These mice likely mimic the 30 percent of colon cancer patients and 10 percent or so of the human population who have loss of imprinting of IGF2. Only the Princeton mice have been crossed with the APC mice. Both the Princeton and the Swedish mice have the extra precursor c...

Spider Venom Could Yield Eco-Friendly Insecticides

...e approach is to create chemical insecticides that mimic the action of spider toxins. Many insects have developed immunity to DDT and other chemical controls because most insecticides are neurotoxins that act against only a small number of nervous system targets. King's spider-venom cocktails could be desi...

Purdue proves concept of using nano-materials for drug discovery

...archers are developing synthetic cell membranes to mimic the real thing and then plan to use those membranes to create chips containing up to 1 million test chambers. Each chamber would be covered with a membrane containing the proteins, and the chambers could then be used to search for drugs that deactiva...

Scientists discover the cellular roots of graying hair

...tap into thisdeath pathway, thereby using drugs to mimic the aging process, tosuccessfully treat melanoma.?The team also made mice lacking a gene, MITF that regulates Bcl2. Thesemice also went gray, but more gradually than did the mice that had noBcl2. The loss of MITF activity, the investigators say, appe...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

...tap into thisdeath pathway, thereby using drugs to mimic the aging process, tosuccessfully treat melanoma.?The team also made mice lacking a gene, MITF that regulates Bcl2. Thesemice also went gray, but more gradually than did the mice that had noBcl2. The loss of MITF activity, the investigators say, appe...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

...tap into thisdeath pathway, thereby using drugs to mimic the aging process, tosuccessfully treat melanoma.?The team also made mice lacking a gene, MITF that regulates Bcl2. Thesemice also went gray, but more gradually than did the mice that had noBcl2. The loss of MITF activity, the investigators say, appe...

Elephants imitate truck noises, other animals

...ian elephants in a Swiss zoo, was a nearly perfect mimic for the chirp-like calls of his long-time zoo mates. The chirps are made by Asian elephants but not by African elephants. Calimero often mimicked the chirps but rarely made any other sounds. "Many species with similar social systems as elephants use...

Elephants imitate sounds as a form of social communication

...ian elephants in a Swiss zoo, was a nearly perfect mimic for the chirp-like calls of his long-time zoo mates. The chirps are made by Asian elephants but not by African elephants. Calimero often mimicked the chirps but rarely made any other sounds. "Many species with similar social systems as elephants use...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

... deficient in both growth hormone and in IGF-1. To mimic the rise in growth hormone and IGF-1 during adolescence in normal rats, some of these deficient rats were given growth hormone while they were between 4 and 14 weeks of age ?rat adolescence. Then hormone treatment was stopped and the animals had lowe...

Tiny scaffolding allows stem cells to become working fat cells

...le useful, these "two-dimensional" patches fail to mimic all the tasks performed by cells in vivo. Specific genes, proteins and hormones normally produced by healthy cells are often absent in two-dimensional colonies. "The PET fibers are spun out onto a mat that resembles the intracellular matrix that bon...

Polymers with copper show promise for implanted sensors

... this problem about eight years ago, was to try to mimic what occurs in the human body to prevent clotting on the walls of your own blood vessels," said Meyerhoff. "Your endothelial cells---the cells that line all of your blood vessels---generate nitric oxide. The nitric oxide produced in this layer of cel...

Insight into natural cholesterol control suggests novel cholesterol-lowering therapy

...earchers. The new findings suggest that drugs that mimic lanosterol--given along with statins--may improve the drugs' long-term ability to lower cholesterol by stimulating reductase degradation. ### The other members of the research team include Bao-Liang Song and Russell A. DeBose-Boyd from University o...

Stem cells from brain transformed to produce insulin at Stanford

...om the brain can form insulin-producing cells that mimic those missing in people with diabetes, according t...d to the environment. These cells don't perfectly mimic human islet cells. Kim's cells made some, but not all, proteins normally made by islet cells, and th...

To control germs, scientists deploy tiny agents provocateurs

...well and her team are designing new compounds that mimic acylated homoserine lactones (AHLs), a natural molecule that is used by more than 50 species of bacteria to "talk." Researchers have so far studied around 15 variations of AHLs. In particular, the UW chemists are synthesizing molecules that interact ...

Nano-bumps could help repair clogged blood vessels

...tter if their surfaces contained "nano-bumps" that mimic tiny features found in living tissues. The resear...s larger or none at all. The nanometer-scale bumps mimic surface features of proteins and natural tissues, prompting cells to stick better, Webster said. "I...

New understanding of DNA repair may pave way to cancer treatments

...tudies are devoted to screening for compounds that mimic the peptide's actions and to allow for further development of the peptide toward clinical assessment. "Until our recent studies, we were certain that the mechanism by which ATF2 affects melanoma growth was primarily through its established function ...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...d microbiology at Duke. "Now, we have been able to mimic some of that instability in yeast cells and can begin to ask whether there is anything special that defines those places where chromosomes tend to break." Organisms normally exhibit extremely low rates of mutation and chromosomal rearrangements. Con...

Disease progression model of pancreatic cancer developed by Penn researchers

...l changes in tissue, this model appears to closely mimic the human disease," says Hingorani. Clinical symptoms in the mutant mice mirrored those displayed in pancreatic cancer patients, such as abdominal swelling and muscle loss. Similarly, the progression of pancreatic cancer metastases paralleled that s...

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