Viral protein influences key cell-signaling pathway
...al protein." HTLV-1 infects an estimated 15 to 20 million people worldwide. In about five percent of them, the infection will lead to adult T cell leukemia or lymphoma (ATLL). ATLL is an aggressive disease characterized by a long latent period and the proliferation of T lymphocytes. The virus is spread by s...Molecular models advance the fight against malaria
...rrently at risk of the disease and approximately 2 million people, mostly children, are killed by malaria annually worldwide. Today marks Africa Malaria Day, organized to promote awareness of the disease in a country where a child is killed every 30 seconds by malaria. Investigating ways to counter the muta...Reducing malarial transmission in Africa
There are 300 million cases of malaria each year worldwide, causing one million deaths. Around 90% of these deaths occur in Africa, mostly in young children. One of the greatest ch...Alaskan puzzles, monitoring provide insight about North Pacific salmon runs
...mon and their ecosystems, has received nearly $2.4 million from the Gordon and Betty Moore Foundation to expa...n-producing river. It has had runs of more than 50 million sockeye salmon in the past, which is more valuable than all the salmon in the lower 48 combined back...Nanoscale Diagnostic Sets Sights on Alzheimer's
...DLs. According to the researchers, BCA is about 1 million times more sensitive than the next best thing ?standard enzyme-linked immunoassays (ELISAs). ELISAs do not have the sensitivity required to detect ADDLs in cerebrospinal fluid. BCA could eventually be configured to detect hundreds of diseases simult...Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
...esterol-lowering statins--taken by an estimated 10 million people each day to protect against coronary artery disease and reduce the incidence of heart attacks--limit cholesterol synthesis by inhibiting reductase function, he said. As a result, cells take up more cholesterol from the bloodstream, lowering it...Low level of extinction during ice age linked to adaptability
...ce ages of them all, which occurred from about 330 million to 290 million years ago, late in the Paleozoic Era. The likely answer: because those aquatic life forms that did ...Transgenic plants remove more selenium from polluted soil than wild plants, new tests show
...lenium-polluted soil. "Field conditions involve a million different variables, from weather to soil conditions, so results can be radically different than those in the lab," said Norman Terry, professor of plant and microbial biology at UC Berkeley's College of Natural Resources and co-lead author of the st...WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas
...habilitation strategy, WHO urgently requires US$67 million for activities through the next six months. Notes to editors The tsunami in Southeast Asia, has at least in some areas, led to environmental disturbance of the kind that would typically be associated with increased mosquito breeding. While pools of...Light therapy may combat fungal infections, new evidence suggests
...olution of these light-sensing genes more than 400 million years ago may have had major significance for fungal colonization of land, at a time when UV irradiation was particularly intense. ...Glow-in-the-dark zebrafish at UH hold keys to biological clocks
... Neuroscience and is currently funded under a $1.2 million National Institutes of Health grant through 2007 as the principal investigator on "Genetic analysis of zebrafish circadian rhythmicity," under which this latest study falls. ...Buying Time Through Hibernation on Demand
...illed with normal room air laced with 80 parts per million of hydrogen sulfide, a chemical normally produced in humans and animals that is believed to help regulate body temperature and metabolic activity. Within minutes of breathing the hydrogen sulfide and room-air cocktail, the mice stopped moving and ap...U-M team recovers ancient whale in Egyptian desert
...illed with normal room air laced with 80 parts per million of hydrogen sulfide, a chemical normally produced in humans and animals that is believed to help regulate body temperature and metabolic activity. Within minutes of breathing the hydrogen sulfide and room-air cocktail, the mice stopped moving and ap...Researchers uncover sequence of major rice pathogen
...sible each year for killing enough rice to feed 60 million people worldwide. In the Nature paper, Dean and his co-authors shed some light on the adaptations required by a fungus to cause disease. The researchers identify novel receptors that allow the fungus to recognize its environment; secreted proteins t...Researchers make gains in understanding antibiotic resistance
...g that hospitals in the United States see some two million cases of antibiotic-resistant infections each year; 90,000 patients die annually from such infections. In their experiments, Steitz and his colleagues used x-ray crystallography to do high-resolution structural analyses of the large ribosomal subuni...Scientists identify genetic pathways essential to RNA interference
..., with an annual research budget of more than $450 million and major research centers in AIDS, cardiovascular research, cancer, cutaneous biology, medical imaging, neurodegenerative disorders, transplantation biology and photomedicine. In 1994, MGH and Brigham and Women's Hospital joined to form Partners Hea...Super predators and mass extinctions
...xtinctions seem to occur on Earth roughly every 26 million years, leading some scientists to propose that the...model can lead to cycles that correspond to our 26 million year mass extinctions. Previous models that do not show these sorts of cycles could be faulty, acco...Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells
...re rare ?fewer than 5,000 births combined out of 4 million per year in the U.S. ?they are best treated if patients are diagnosed and treated in early infancy, said Kurtzberg. In fact, transplantation in newborns yields the best long-term outcomes and newborns tolerate the transplants more easily than older b...Sickle cell and protection against malaria
...mated that cases of malaria causes approximately a million deaths yearly, the overwhelming number of which are young children in sub-Saharan Africa. It has been known for many years that in those areas most afflicted by malaria the gene for sickle cell hemoglobin (HbS) occurs very frequently. The protection ...Small species back-up giant marsupial climate change extinction claim
...ed the globe in the Pleistocene epoch, between 1.8 million and 10,000 years ago. In the northern hemisphere ...ndscape, while in Australia - which evolved for 40 million years in isolation - giant marsupials ruled. Current theories suggest that between 50,000 and 20,00...