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Tag: "might" at biology news

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...r, it is possible that in the future, drug therapy might be used to "turn down" the mechanism, decreasing cholesterol levels and heart disease risk, explained Spiegelman, who is also a professor of cell biology at Harvard Medical School. Saturated fats are found in fatty cuts of meat, whole-milk dairy pro...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

...repair capacity and what effect such interventions might have on risk." In an editorial, Marianne Berwick, Ph.D., M.P.H., of the University of New Mexico in Albuquerque, and Paolo Vineis, M.D., M.P.H., of Imperial College in London and the University of Torino in Italy, discuss the difficulties in designi...

Spleen may be source of versatile stem cells

...pital (MGH) researchers discovered that the spleen might be a source of adult stem cells that could regener...ying a fairly minorrole in regenerative medicine - might contain a population of potentialislet stem cells.In their pursuit of that finding, the MGH research...

Growth in the sea comes down to a struggle for iron

... has been some speculation that iron fertilization might be useful in reducing the threat of global warming. However, this idea remains highly controversial in scientific circles given the very limited understanding of these unique systems, says Wells. Wells specializes in chemical oceanography and has wo...

Neuronal 'traffic jam' marks early Alzheimer's disease

...said their findings could provide information that might be used to develop drugs to preserve the molecular...ry." Goldstein theorized that Alzheimer's disease might develop spontaneously in people without an overt genetic defect, as the transport machinery in their...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...the feeder layer in the culture.A further solution might be a short-term culture in heat-inactivatedserum from the actual patient who is going to receive the therapy, thescientists said. However, it may still prove difficult to completelyeliminate the Neu5Gc, because is has become metabolically incorporate...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...re any immunologic properties that differ and that might provide a route to new vaccine or drug strategies," Harrison says. ...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...gto Holtzman, the new results suggest that plaques might not just causedamage but also somehow actively maintain it.The study, will appear in the Feb. 5 issue of the Journal of ClinicalInvestigation.Lead author Robert Brendza, Ph.D., research instructor, began theexperiment with one key question: how did c...

Key molecule in plant photo-protection identified

...gto Holtzman, the new results suggest that plaques might not just causedamage but also somehow actively maintain it.The study, will appear in the Feb. 5 issue of the Journal of ClinicalInvestigation.Lead author Robert Brendza, Ph.D., research instructor, began theexperiment with one key question: how did c...

Timing is everything: First step in protein building revealed

...was released from the ribosome, or thatits release might serve an important purpose, so this was a completelyunexpected result," says graduate student David Maag, first author ofthe paper."It's impossible to know for sure whether eIF1 is released completelyin living creatures, but in our laboratory experim...

Scientists detect probable genetic cause of some Parkinson's disease cases

... disease.Further study of how this gene works also might help scientistsidentify new treatments."In addition to Dr. Singleton, the collaborative work was spearheaded byWilliam C. Nichols, Ph.D., of Cincinnati Children's Hospital, TatianaForoud, Ph.D., of Indiana University Medical Center, Indianapolis, and...

New Technique for Tracking Gene Regulators

... locations for CREB binding sequences orgenes that might be regulated by CREB.Using this technique, the scientists have identified some 6,302genome-binding sites for CREB, including many that are located nearknown genes. Genes identified as being regulated by CREB using thismethod include the gene responsi...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...sought to study thepossibility that ubiquitination might play a part in rendering theunbound Notch receptor inert. Their attention was drawn to Nedd4 (amember of the ubiquitin ligase family of molecules that directly bindto proteins marked for degradation), as it had previously been shownthat Nedd4 plays a...

U-M scientist to talk about tissue engineering at AAAS

...on, and we don't know if the rules of regeneration might be totally different," said Paul Krebsbach, associate professor at the U-M School of Dentistry. Krebsbach is scheduled to participate in a panel titled "Tissue Engineering for the Head and Neck," at the AAAS annual meeting Feb. 17-21 in Washington, ...

Novel Enzyme Shows Potential As An Anti-HIV Target

... a nuclear enzyme, like Tat, suggesting that SIRT1 might work similarly in living cells. Ott and colleagues went on to show that transcription via Tat occurs in the presence of SIRT1, but not when SIRT1’s catalytic center is removed. Experiments using cells taken from transgenic mice lacking SIRT1 demonst...

The secret lives of whales

...ermal vents. Smith immediately suspected that they might be related. Today, Smith and others have traced t...pback whales sing—and Payne speculated that whales might communicate across oceans. Clark and others have confirmed and expanded upon Roger Payne’s early wor...

Gene therapy converts dead bone graft to new, living tissue

...ly converted in just a year, and that a human bone might be completely converted in as little as five years. The Musculoskeletal Transplant Foundation has been trying for two decades to conquer the issues complicating bone transplants, and the group has pledged to continue supporting Schwarz's research. Sc...

Jefferson Virologists Coax HIV Out of Hiding

... lead to improvedtreatments for HIV infection, and might be a step toward complete viraleradication. TheJefferson team reports its findings January 4, 2005 in the Journal ofClinical Investigation.Dr. Pomerantz, who is director of Jefferson’s Center for Human Virologyand Biodefense, and his co-workers took...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...ng the human cell receptors, an indication that it might also work in people. Scientists made another set ...h and clinical testing would be required before it might be used in humans. He also is interested in applying this approach to develop a preventive treatment...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...first step toward understanding howexposure to BCE might affect human nerve cell development--knowledgethat...BCE affectshuman nerve cell development and how it might relate to neurologicaldisorders. "We can clearly state that we found an increase in acomponent of PK...

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