microarray 2 4

Tag: "microarray" at biology news

Powerful technique for multiplying adult stem cells may aid therapies

...tain the stem cells so dramatically? Zhang used a microarray platform to search for genes that were active in these newly discovered cells, but not active in similar neighboring cells. Some such genes, he reasoned, might encode secreted proteins that sustained stem cells. Eventually, he located a number of suc...

Study suggests that publicly available genome data may contain small but significant errors

...and New York University describe a high throughput microarray technique that involves testing many samples simultaneously and which can be used to assemble physical maps and validate genomic sequence assemblies. The findings appear in the latest issue of the Journal of Computational Biology. The research w...

Darkness unveils vital metabolic fuel switch between sugar and fat

...tate of torpor. Lee and colleagues started with a microarray analysis of gene expression in the livers of mice subject to the usual light-dark cycle and those kept in the dark for 48 hours. One gene fired up in the dark ?procolipase, which produces an enzyme (CLPS) required for degrading dietary fat. Expre...

First SCID gene chip to be introduced at Academy meeting on immunodeficiencies

...s part of Dr. Jennifer Puck's report on the use of microarray technology in developing genetic screening for SCI...ion in developing genetic screening for SCID using microarray technology. Chaim Roifman, M.D., Division of Immunology & Allergy, Hospital for Sick Children, ...

Ticks, flukes, and genomics: Emerging pathogens revealed

...rforming, or planning to perform, whole genome DNA microarray analysis and proteomic analysis of these bacteria." In addition to comparing genomes, the current study used those genomes to reconstruct the metabolic potential (the ability to use and produce energy and compounds) of five bacteria, representing t...

Utah researchers confirm chromosome may harbor autism gene

...rs. The researchers used a gene chip similar to a microarray to search for geneticmarkers of autism. They used a coated glass chip from Affymetrix, Inc. This chip has 10,000 short segments of DNA with known gene sequence variations, called single nucleotide polymorphisms (SNPs), attached to 3/8 by 3/8-inch a...

Oh, rats! Designer animals reveal possible heart disease genes

...eart disease. In total, the scientists built 2,200 microarray gene expression profiles from these designer rats-...r biologist Norman Lee led the team in using a DNA microarray technique to compare the expression of more than 22,000 genes among the hypertensive, healthy, and d...

Minor mutations in avian flu virus increase chances of human infection

...ion deaths worldwide. Using a recently developed microarray technology-hundreds of microscopic assay sites on ... jump to human-to-human transmission. The glycan microarray technology, which was used to identify the mutations which could enable adaptation of H5N1 into the ...

Cloned stem cells prove identical to fertilized stem cells

...fertilization-derived stem cells. With a series of microarray chips, Brambrink measured which genes were active and which were silent in both kinds of cells. To ensure the accuracy of his results, he compared five lines of cloned stem cells with five fertilization-derived stem cell lines. "The results are ver...

Scientists seek to unwrap the sweet mystery of the sugar coat on bacteria

...and determine which sugars coat the bacteria. The microarray technique worked fast enough that the researchers ...s on bacteria surface over time." Mahal says the microarray method could provide an important tool for identifying bacteria and diagnosing infection. It will al...

Stanford/Packard scientist's data-mining technique strikes genetic gold

... in this case, gene expression data from so-called microarray experiments - to pinpoint genes likely to be invol... automatically categorize the tens of thousands of microarray experiments in a single database based on the terms, or concepts, used by the submitter to describe ...

Predicting chemotherapy outcome

...ected from 13 patients with colorectal cancer. The microarray analyses were carried out before the patients were treated with combined chemotherapy of folinic acid, 5-fluorouracil and irinotecan. Imbeaud and colleagues identified 679 genes that were differently expressed in patients who subsequently responded ...

Escapee farmed salmon infiltrate fitter wild populations

... this research paper explain: "Using a 3,557 genes microarray and a unique set-up in which farmed and wild salmon of the corresponding natural population were grown in identical conditions, we document for the first time genome-wide changes in transcription profiles that evolved in parallel between farmed strai...

'Genetic network' guards against lethal DNA damage

...atches one of the barcodes. Machines then read the microarray to identify which of the sensors found matching ba...other are knocked out, the yeast cell dies and the microarray doesn't record that cell, Boeke noted. That means the two genes interact with each other, he said. ...

Virginia Bioinformatics Institutes launches microbial database

...rabidopsis. In addition, support for proteomic and microarray data will be added, which will be linked to the functional genomic data and the genome sequences. P. ramorum, also known as sudden oak death, is a serious fungal pathogen that has attacked and killed tens of thousands of oak trees in California and ...

Common molecular 'signature' identified in solid tumors

...and in the normal tissue surrounding them. Using microarray technology developed at Ohio State , lead investigators Stefano Volinia and George Calin found 137 different miRNAs expressed in at least half of the cancers, with 43 miRNAs allowing scientists to distinguish the difference between normal and maligna...

UCR researchers design chip that can improve citrus varieties

...nt pieces of citrus DNA are deposited on a grid or microarray using methods similar to those used to produce com... tissue. The chip is the first commercial citrus microarray and allows analysis of expression of more than 20,000 different genes. The array will also be used ...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

... researchers at Thomas Jefferson University used a microarray chip containing probes for most of the known miRNA...ll fall into those groups." Believing that a gene microarray test might provide additional information, a team of researchers led by Wang-Rodriguez picked 512 ge...

AIDS-related cognitive impairment exists in two separate forms

... researchers at Thomas Jefferson University used a microarray chip containing probes for most of the known miRNA...ll fall into those groups." Believing that a gene microarray test might provide additional information, a team of researchers led by Wang-Rodriguez picked 512 ge...

Researchers identify genes in fruitflies that may shed light on human cancer spread

...one gene at a time. Whole genome studies, like the microarray analysis used in this study, allow researchers to identify genes that share similar functions in a way that mutational analysis cannot. And, whole genome approaches can look at most of the genes in the genome at one time. As part of their previous w...

1 2 3 4 5 6