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Tag: "microarray" at biology news

New technique helps identify multiple DNA regulatory sites

...only three steps and could reduce the cost of each microarray to under $50. "This would completely revolutionize diagnostics," said Stellacci. With the ability to mass produce these devices and thus make DNA analysis routine, "we could know years in advance of cancer, hepatitis, or Alzheimer's." Another benefi...

Genomatix, AAAS ink agreement

...ence analysis. It is an important component of the microarray data analysis pipeline offered by Genomatix and en...o a researcher's set of genes (for example, from a microarray analysis) generates the full biological network, allowing for functional analysis of the most releva...

U-M scientists discover identifying markers for primitive blood-forming stem cells

...s stem cells differentiate." Kiel and Yilmaz used microarray analysis to measure levels of gene activity in three types of cells ?hematopoietic stem cells, multipotent progenitor cells and fully developed bone marrow cells. They selected genes that were expressed at higher levels in the HSC population, as oppo...

Researchers discover key to human embryonic stem-cell potential

...me between the Jaenisch and Young labs. Using a microarray technology invented in the Young lab, Boyer and her colleagues analyzed the entire genome of a human embryonic stem cell and identified the genes regulated by these three transcription factors. The research team discovered that while these transcript...

Genomatix Microarray Analysis Pipeline achieves Affymetrix GeneChip compatible?status

...veral products with the Affymetrix Inc. GeneChip® microarray platform and that it has joined Affymetrix GeneChi... is committed to seamlessly integrating its entire microarray analysis pipeline with the Affymetrix technology. The Genomatix line of products which achieved G...

Customized gene chip provides rapid detection of genetic changes in children's cancer

...ancer. Rather than covering the entire genome, the microarray focuses on suspect regions of chromosomes for sign...r genes active in neuroblastoma, we can modify the microarray to include such regions," he added. "We have customized this tool for neuroblastoma, but the approa...

Researchers discover why melanoma is so malignant

...sses. For the second experiment, the team used microarray technology (chips covered with fragments of DNA that can measure gene levels) and found that Slug was expressed in human melanoma. "Really, this isn't that surprising," says Gupta, "when you consider that melanocytes in the skin are direct descendant...

Study reveals genomics of inflammation from severe injury

..., the research team described the development of a microarray technique to analyze the entire genome of white blood cells from healthy volunteers and critically injured patients. Next, the team plans to study gene and protein activity in the white blood cells of a large group of trauma and burn patients over lo...

Study Unlocks Insects?Secret for Love in the Dark

..., the research team described the development of a microarray technique to analyze the entire genome of white blood cells from healthy volunteers and critically injured patients. Next, the team plans to study gene and protein activity in the white blood cells of a large group of trauma and burn patients over lo...

Gene Expression in the Aging Brain

...gene expression, each done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by chan...

Navigating the brain for sense of direction as paradigm for higher cognitive functions

...gene expression, each done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by chan...

Carnegie Mellon scientists create PNA molecule with potential to build nanodevices

...gene expression, each done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by chan...

Microarray technology for tailoring breast cancer therapy

...n profiles of 159 breast cancer patients using DNA microarray analysis. From these samples they identified the g... The researchers suggest that the technique of DNA microarray analysis could be developed to help breast cancer patients who do not benefit from adjuvant therapy,...

Mapping alcohol brain damage

...drinks a day. The group analyses samples using a microarray analysis, a process they pioneered with human brai...om a DNA sample applied to a microscope slide, the microarray computer produces about 50,000 coloured spots showing which genes are expressed or switched on in th...

New U. of Colorado at Boulder flu chip may help combat future epidemics, pandemics

...imately one-hundredth of an inch in diameter. The microarray is then immersed in a wash of influenza gene fragm...nfected fluid bind to specific DNA segments on the microarray like a key in a lock, indicating both a match and that the virus signature is present, she said. Th...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

...w findings further establish an important role for microarray gene profiling as a predictor of clinical outcome ... Their work makes use of a DNA technology known as microarray analysis, in which genes expressed by cancer cells are labeled and applied to a glass slide containi...

Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool

...w inspired a revolutionary method to transform DNA microarray analysis, a common technology used to understand g...blends experiment and computation, strengthens DNA microarray analysis, according to its Carnegie Mellon University inventor, who is publishing his findings in th...

Setting the standard for computer models of life

...orked very well for other fields - for example the microarray community, by enabling authors, publishers and data providers to work together to improve access to meaningful biological information." ...

Common molecular 'signature' identified in solid tumors

...and in the normal tissue surrounding them. Using microarray technology developed at Ohio State , lead investigators Stefano Volinia and George Calin found 137 different miRNAs expressed in at least half of the cancers, with 43 miRNAs allowing scientists to distinguish the difference between normal and maligna...

Powerful new tool for studying brain development

...mors in children. The team used a technique called microarray analysis to study gene expression patterns in samples of human brain tumors called ependymomas. By comparing the gene expression patterns in human ependymomas with those in the normal developing mouse nervous system provided by the BGEM, the St. Jude...

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