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Tag: "microarray" at biology news

Man and mouse share genome structures

...certain major methyl and acetyl tags, and used new microarray technology to identify the underlying genetic sequences associated with the tagged chromatin. Next, they teamed up with Michael Kamal, the co-first author of the paper, Eric Lander, and their Broad Institute colleagues, for the daunting computational...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...nstitutes of Health, shows for the first time that microarray datagenerated in different laboratories can produc...ut in multiple locations and would necessitatethat microarray data produced in different laboratories be combined foranalysis. Even if all procedures and equipmen...

Breakthrough Microarray-based Technology for the Study of Cancer

...n the modification of its gene-expressionprofiling microarray technology to improve its utility for DNA analysisapplications. This new platform provides high sensitivity, enabling CGHresearchers to reliably identify the single copy deletions inchromosomes that have been the most difficult to detect.Additionally...

Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6

...fic Officer of IOS. "The feature set required for microarray analysis is becoming moremature so we have been concentrating more on proteomics data recently.For example Silicon Genetics new GeneSpring?7 includes Support VectorMachines (SVMs). SVMs have been available in GeneLinker Platinum formore than a year a...

Scientists decipher genome of fungus that can cause life-threatening infections

...ptococcusresearch community already has designed a microarray and has formed aconsortium to further investigate the function of C. neoformans genes.The sequence data also provides the foundation for a broader genomeproject that aims to define the molecular basis for the C. neoformansspecies cluster, which inclu...

Nanogen Issued Patent for Electronic Microarray With Memory

...ivation and array usage directly on the electronic microarray cartridge. "This addition to our growing intellectual property portfolio illustrates our ability to develop differentiated advanced diagnostic products that add value to the company and to research and clinical laboratory customers," said Howard C. ...

Scientists reveal molecular secrets of the malaria parasite

... the integration ofdraft genome sequence data with microarray and protein expressiondata," says Carlton. "This project also shows the power ofcollaboration between international institutes with different areas ofexpertise. It was remarkably productive collaboration."...

Alcohol's effects on gene expression in the central nervous system

...on to produce intoxication. Scientists can now use microarray technology to study brain function gene by gene. S...alyze more than a handful of these genes, however, microarray technology has changed that." Symposium speakers at the June 2004 Research Society on Alcoholism me...

An entropy-based gene selection method for cancer classification using microarray data

...based iterative algorithm for selecting genes from microarray data that are able to classify various cancer sub-types with high accuracy. In addition, the feature set obtained is very compact, that is, the redundancy between genes is reduced to a large extent. This implies that classifiers can be built with a s...

PANTHER Protein Classification System Database 5.0

...ology) and knownpathways. Its main use is probably microarray analysis - it incorporateautomated GO surrepresentation analysis with graphical output. Best ofall, its available freely . A paper describing the Database is available freely in the Nucleic acids research Journal . AppliedBiosystems (NYSE:ABI), an...

Agilent Technologies releases automated literature search tool for biology researchers

...biological entities, such as genes and proteins. A microarray or an LC/MS-proteomics experiment can typically result in hundreds of genes and proteins of interest. Biologists can use the new plug-in to avoid the daunting task of manually searching for each gene and protein in the scientific literature and paten...

Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance

...nical research institutes with advanced Affymetrix microarray technology. Karolinska Institutet will have access to a number of new microarray technologies from Affymetrix, including the Mapping 100K. The 100K is the first in a family of produ...

Affymetrix and Stratagene Announce Strategic Software Alliance

...rt to bring to market breakthrough gene expression microarray technology. By partnering with other thought leaders in our field, we believe we have the opportunity to position our technology as a standard for expression analysis." ...

Asthma gene clusters identified

...ttacks," Dr. Hershey said. Previous studies using microarray technology have been conducted using RNA from adults with asthma, but this approach has not been successfully used in human studies involving children with asthma. In pediatrics, it is difficult to obtain tissue in sufficient quantities for analysis,...

Viral protein influences key cell-signaling pathway

...vel of p12 protein. The researchers then used gene microarray technology to identify which cellular genes out of 33,000 become either more or less active due to the p12 protein. The researchers found that p12 altered the activity of a variety of genes linked to chemical pathways that control cell signaling, pr...

Products containing specific probes for detecting alternative splice forms protected

...y the United States Patent and Trademark Office on microarray products allowing the specific detection of mRNAs produced by alternative splicing, covering microarrays optimised for the discovery of alternative RNA splicing events. The patent protects the probe configuration of a unique set of five oligonucleoti...

Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences

...luidics patent estate with Affymetrix' GeneChip(R) microarray technologies. The license extends to the manufacture and sale of GeneChip brand products in all areas of application, including research, diagnostics and applied genomics applications. In exchange for the license, Affymetrix will pay upfront licensin...

GeneNotes - A novel information management software for biologists

Analyzing microarray data - or even a simple biological network - can get you lost - quick. Tons of genes, tons of synonyms for each, tons of known interactions, with even more being unknown, tons of database with tons of information... and your job is to make sense of t...

Researchers rein in regulatory RNAs

...these unique transcripts. Employing a custom-made microarray chip designed to detect strand-specific expression of 1947 SAT pairs, the researchers discovered that most of the SATs were widely expressed in mouse brain, heart, and testis, as well as in mouse embryonic stem cells and fibroblasts. While some SATs ...

CoPub Mapper: mining MEDLINE based on search term co-publication

High throughput microarray analyses result in many differentially expressed g...random chance. To test grouping of genes from real microarray data, 221 differentially expressed genes from a microarray experiment were analyzed with CoPub Mappe...

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