mice 2 5

Tag: "mice" at biology news

Angelman syndrome deficits rescued in mice

.... The researchers decided to breed the Angelman mice with the CaMKII mutant mice to see if counteracting the CaMKII inhibition would alleviate the neurological problems. The rese...

Early-stage sperm cells created from human bone marrow

...his discovery, particularly as our earlier work in mice suggests that we could develop this work even furt...e embryonic stem cells and used these to fertilise mice eggs, resulting in seven live births....

Antibody therapy prevents type 1 diabetes in mice

...essfully prevented the onset of type 1 diabetes in mice prone to developing the disease using an antibody ... Pitt researchers treated non-obese diabetic (NOD) mice with an antibody -- a type of protein produced by the immune system that recognizes and helps fight ...

Scientists clone mice from adult skin stem cells

...lt stem cells taken from skin can be used to clone mice using a procedure called nuclear transfer. The fin...using adult stem cells for reproducible cloning of mice that survive until adulthood. By using cells from the same mouse and performing the experiments on t...

Tumor-suppressor gene is critical for placenta development

...es critical for survival (the gestation period for mice is 19 days). Interestingly, the researchers also produced some mice in which the Rb gene was present in the placenta stem cells but destroyed in cells produced by them....

Putting an old drug to a new use

...e body deal with too much iron. "We observed in mice with iron overload that nifedipine helps mobilise iron from stores in the liver and enhances its excretion into the urine," says Weiss, an EMBL alumnus who now heads a lab at the Department for General Internal Medicine at the University of Innsbruck...

New cell type identified in cancer development

...ly or intravenously into three groups of mice. The mice represented different levels of immune function: O...une deficient mice, a second group was composed of mice whose immune systems had been knocked out by radiation, but had been partially restored by an infusi...

Gene that makes people 'early to bed and early to rise' demystified

... set to such an early wake-up time. In studies of mice carrying the human FASPS gene, the researchers fou...that the human gene inserted into otherwise normal mice causes them to rise early, symptoms that mirror those in people with FASPS. In contrast, a mutation ...

Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight

... Sanchez-Alavez and Tamas Bartfai, discovered that mice genetically altered to lack a molecule known as th...o weight increases of up to 30 percent relative to mice with the receptors. The EP3 receptor is one of four types of receptors for prostaglandin E2 (PGE2)...

Researchers urge monitoring of bone health during chemotherapy

...echer and her colleagues found that when they gave mice an eight-day course of the growth factor, called granulocyte colony-stimulating factor (G-CSF), the mice lost bone mass and experienced increased bone tumor growth when injected with cancer cells. Their st...

Finnish scientists discovered a new approach to treat virus-induced lymphomas

...3a is an efficient treatment for KSHV-lymphomas in mice and suggest a novel therapeutic strategy for treatment of these fatal virus-induced malignancies also in humans....

White blood cells in lung produce histamine seen in allergies

...oduced as a result of inflammation. The study in mice is the first to show that lung neutrophils can pro... and his team exposed two different populations of mice to mycoplasma, a common respiratory infection in rodents and humans. One population had a genetic ab...

Carnegie Mellon University research shows how sensory-deprived brain compensates

... In her study, Barth recorded brain activity in mice with various degrees of whisker removal. As a first step in her research, Barth removed all but one whisker and recorded neural activity in a brain region located on the opposite side of the animal. (Flicking a whisker on one side of a mouse stimulat...

Gene therapy for blindness clears hurdle in mice

...a researchers have used an experimental therapy in mice to shut down a gene that plays a crucial role in a leading cause of inherited blindness. The technique, detailed in an upcoming issue of Vision Research, involves injecting the eye with a bit of genetic material called interfering RNA, which helps d...

HIV protein enlisted to help kill cancer cells

...gmented the cell-killing effect of radiation. When mice with malignant tumors were treated with TAT-Bim, their tumors shrank, and they survived longer than mice that didn't get the treatment. After 40 days, 80 percent of mice receiving TAT-Bim were alive compar...

Scientists to track impact of Asian dust and pollution on clouds, weather, climate change

...ghes Medical Institute have engineered a strain of mice whose olfactory brain cells "fire" when exposed to...aid. The light-producing gene inserted into the mice is taken from the water-dwelling microorganism Chlamydomonas reinhardtii, which, as a plant, needs s...

Trojan horse strategy defeats drug-resistant bacteria

...ments and eliminate life-threatening infections in mice by interfering with a key bacterial nutrient, according to research led by a University of Washington scientist. The joint project, conducted at the UW, the University of Iowa, and the University of Cincinnati, will be featured in the April 2 issue o...

Common algae helps illustrate mammalian brain electrical circuitry

...ghes Medical Institute have engineered a strain of mice whose olfactory brain cells "fire" when exposed to...aid. The light-producing gene inserted into the mice is taken from the water-dwelling microorganism Chlamydomonas reinhardtii, which, as a plant, needs s...

How genetic malfunction causes a form of retardation

...rchers also studied the effects of the mutation in mice engineered to mimic the human disorder. Like humans with NS, the mice had only one mutant copy of the SHP-2 gene, while the other was normal. The researchers observed in ...

Gallium: A new antibacterial agent?

... biofilms. Furthermore, inhalation of Ga protected mice from both acute and chronic P. aeruginonsa lung infections. As Ga is already FDA approved for the treatment of hypercalcemia of malignancy, these data suggest that Ga might be a promising new therapeutic for the treatment of infection with P. aerugin...

1 2 3 4 5 6 7 8 9 10