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Tag: "methods" at biology news

Association of herpesvirus with lung disorder questioned

...rom that in the United States. The sensitivity and methods of the tests used in each study may also have differed. "We hope that our results provide scientists with another perspective on the potential causes of primary pulmonary hypertension," Dr. Katano said. "Further studies are required to clarify the p...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...s therefore possible to imagine the development of methods oftreatment for SLE based on blocking the function of the thyrosinkinaseenzyme," explains Lars Rönnblom.The other gene codes for a transcription factor, which also plays animportant role in regulating the interferon effect. Further functionalanalyses...

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

...esurface' which is a major disadvantage of current methods that infusethe cells into the structure after it has been built."The problem is getting cells into the interior of these constructionsas they naturally stick to the sides of whatever they are beinginserted into. If they stick to the sides then this l...

Protein discovery could unlock the secret to better TB treatment

... in the TB bacteria could allow the development of methods to 'wake-up' all dormant bacteria in a patient allowing antibiotics to kill the bacteria and cure the disease." The team includes Prof Brian Henderson at the UCL Eastman Dental Institute, Nicholas Keep from Birkbeck, University of London, and John W...

W.M. Keck Foundation funds study of friendly microbes

...rsity of life on Earth, as well as help create new methods to diagnose and treat patients with common and unc...tubes. They are also developing new computational methods for mining genome sequence data so that bacterial species can be more rapidly and accurately classif...

Novel technology detects human DNA mutations

...ication or enzymatic interventions ?two widespread methods currently used to perform such analyses. "Nanosphere's new SNP analysis methodology for whole genomic human DNA is a powerful example of the versatility of our proprietary ClearReadTM nanoparticle technology," said William Moffitt, Nanosphere's Pre...

New, automated tool successfully classifies and relates proteins in unprecedented way

...egie Mellon University, outperformsexisting visual methods to localize proteins inside cells, saysProfessor Robert F. Murphy, whose report, "Data Mining in Genomics andProteomics," appears in an upcoming special issue of the Journal ofBiomedicine and Biotechnology. "Ourapproach really enables the new field ...

Neuronal 'traffic jam' marks early Alzheimer's disease

...reflect transport function, there could be imaging methods that might be helpful for diagnosis," he said. "And, if these findings continue to hold for humans, the transport machinery could be a target for drugs to preserve that machinery." The researchers plan to continue their exploration of the transport ...

Termites feed through good vibrations

...the wood they eat may provide opportunities to new methods of reducing infestations in homes and also may provide insights into the "cocktail party effect" of signal processing ?how to ignore most noise but have some signals that trigger attention ?that may prove useful in artificial intelligence. CSIRO ent...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...human Neu5Gc molecule. Alltraditional culture-dish methods used to grow all human embryonic stemcells include animal-derived materials, including connective tissuecells (so-called "feeder layers") from mice and fetal calf serum."The human embryonic stem cells remained contaminated by Neu5Gc evenwhen grown in...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...rial neighbors. Because the parasite uses the same methods to kill bacteria as it uses to damage human cells and cause disease, the level of certain bacteria in the colon can be an important determinant of the amoeba's virulence. Biomedical scientists say the E. histolytica sequence will help researchers de...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

...he findings were notadequately followed up because methods to do so were unavailable at thetime. The statistically strong association with Kawasaki disease,however, was "quite surprising." Noting that previous attempts to linkKawasaki disease to bacteria or other viruses had failed and thusjustified healthy ...

New Technique for Tracking Gene Regulators

...way. Scientists can use traditionalgene-sequencing methods to decipher the sequence of A, T, G, and C onthese fragments and then locate their original positions on the genome,but it is a slow and somewhat expensive process. Other methods, such asmatching the pieces to their compliments on microarrays, are li...

Imaging Lymph Nodes with Nanoparticles

...such asmagnetic resonance imaging (MRI). All these methods have problems; someare very invasive, others are very time consuming, and none arecompletely reliable.However in one of the more exciting crossovers from chemistry intomedicine, researchers have developed nanoparticles to improve thediagnostic accura...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

...sign, and CEO of DermaPlus, Inc. The patent covers methods for recovering and reconstituting genes from "degraded" DNA samples, and could allow scientists to reassemble everything from prehistoric, extinct animals to unsolved crime scenes. "This discovery, when properly applied by our scientists, brings us ...

New Clues Add 40,000 Years to Age of Human Species

...00 years old. Forty years ago, radiometric dating methods were less accurate and suggested an age of roughly 130,000 years. No one was able to securely tie both sets of fossils to the same time period. "Fortunately, small pumice fragments from two sediment layers were perfect for precise isotopic dating,...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...py would be effective ?10 weeks before traditional methods would show a response. "This is an important issue in terms of patient quality of life. Do you want to go through seven weeks of treatment only to find two months later that it had no effect? Using MRI tumor diffusion values to accurately predict th...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

Gene therapy methods that specifically target muscle may reverse the symptoms of a rare form of muscular dystrophy, according to new research in mice conducted by medical geneticists at Duke University Medical Center. Infants born with the inherited muscular disorder cal...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

...lecule.“This work required that we develop new NMR methods in order todetermine the shape of this protein, which undergoes changes as itinteracts with pIgR,?said Rensheng Luo, Ph.D., a post-doctoral fellowin St. Jude Structural Biology and Infectious Diseases and first authorof the paper....

New comparative toxicogenomics database

...lecule.“This work required that we develop new NMR methods in order todetermine the shape of this protein, which undergoes changes as itinteracts with pIgR,?said Rensheng Luo, Ph.D., a post-doctoral fellowin St. Jude Structural Biology and Infectious Diseases and first authorof the paper....

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