UW-Madison scientists zero in on drugs' sweet spots
...e sugars found in natural agents. Critically, the method allows medicinal chemists to investigate the biolo...ace in nature -- and they are very important. This method allows us to rapidly scan the roles of these sugars in complex natural products." The simplificatio...North & South American researchers find architectural abnormalities in T. cruzi ribosome
...pioneered the analysis of ribosome structures by a method he developed for three-dimensional reconstruction of large molecules using electron microscopy and image processing. Levin told him the story of Chagas and the need to know more about the structure of the parasite's ribosome. A ribosome is basically...Most embryos produced during IVF do not result in live births
...is a difficult task unless they can come up with a method in the lab to identify the best embryos. "Some potential methods for screening embryos include using pre-implantation genetic diagnosis and biochemical markers of embryo viability," said Patrizio. "In addition this study should also move the field t...Immune system has evolved to prevent autoimmune disease
... proteins in a healthy cell. The mutation response method employed by our adaptive immune system seems keyed to this number, producing antibodies that are statistically likely to mistakenly bond with healthy proteins slightly less than one in a trillion times, meaning that on average, they recognize only in...NHGRI expands effort to revolutionize sequencing technologies
...m sequencing by synthesis reaction chemistry. This method allows for smaller volumes of materials to be used...This group will develop and implement an efficient method capable of sequencing mammalian size genomes by amplifying single template molecules, and subjecting...Researchers find ways to turn manure into power
...rface manure harvesting by scraping is an accepted method of dust control." ...UNC scientists discover new role for protein as fundamental inhibitor of cell movement
...ration and PAK1 activation, the authors used a new method known as RNAi or RNA interference to knock down or reduce CIB1 expression in various cell lines. Cells with less CIB1 had less PAK1 activation and migrated faster. The authors also showed that the more CIB1 these cells had, the less likely they were ...UW scientists report a new method to speed bird flu vaccine production
...sin team improves upon a previous reverse genetics method (developed by Kawaoka's group in 1999) by signific...he manufacture of vaccines will be important. The method devised by Kawaoka and his colleagues reduces the number of plasmids required to introduce viral gen...Scientists discover new way to look at how molecules twist and turn on water
...al of Physical Chemistry B . "We have developed a method to determine the tilt and twist angles of these molecules at the surface, a characterization that is important for understanding how they might function in various practical applications," Richmond said. "This is a general approach that has broad imp...Complex gene interactions account for autism risk
...combinations," Pericak-Vance added. The analytical method applied by the researchers allowed them to rigorou...the disease." Such findings may ultimately yield a method to screen for individuals at high risk for the disease, she added. "The new findings offer importan...Method slashes quantum dot costs by 80 percent
...scientists at Rice University have developed a new method of replacing the pricey solvents used in quantum d...arly 1990s when researchers at MIT pioneered a new method of producing quantum dots with uniform sizes and well-defined optical signatures. The basic recipe f...Purdue's gold nanorods brighten future for medical imaging
... same time. Because of the two-photon effect, the method might enable scientists to develop advanced "non-linear optical techniques" that provide better contrast than conventional technologies. Cheng is applying the two-photon fluorescence and other non-linear optical effects to develop imaging methods tha...The right drug at the right time
...scientists at Rice University have developed a new method of replacing the pricey solvents used in quantum d...arly 1990s when researchers at MIT pioneered a new method of producing quantum dots with uniform sizes and well-defined optical signatures. The basic recipe f...UF study first to quantify validity of DNA I.D. tool using marine snails
...n identify them, the need for a quick and accurate method of classifying life has never been more pressing, Meyer said. With millions of animal species on Earth, DNA barcoding can be a helpful identification tool for ecologists who may not necessarily be taxonomy experts, he said. "This new technology is s...Climate change will affect carbon sequestration in oceans, model shows
...xide deep into the ocean has been suggested as one method to help control rising carbon dioxide levels in the atmosphere and mitigate the effects of global warming. But, because the atmosphere interacts with the oceans, the net uptake of carbon dioxide and the oceans' sequestration capacity could be affecte...How 'Dirt' Could Educate The Immune System And Help Treat Asthma
...xide deep into the ocean has been suggested as one method to help control rising carbon dioxide levels in the atmosphere and mitigate the effects of global warming. But, because the atmosphere interacts with the oceans, the net uptake of carbon dioxide and the oceans' sequestration capacity could be affecte...New cell transplantation technique restores insulin production in diabetics
...duce insulin in patients with type 1 diabetes. The method is minimally invasive, with few complications. The...rsity of Minnesota in Minneapolis. "This is a safe method of cell transplantation that could potentially become a same-day procedure." In type 1 diabetes, th...Gene therapy works in mice to prevent blindness that strikes boys
...or walk around." Scientists say the gene transfer method eventually could be applied to many eye diseases caused by single gene defects, including a host of retinal disorders. Retinoschisis is usually first detected in boys between 5 and 10 years of age when their vision problems cause reading difficultie...UT Southwestern researchers develop screening test for cells that activate immune system
...irst to create a large-scale, cell-based screening method that identifies which compounds activate immune-response cells that hold promise for future cancer-fighting vaccines. The new screening technique can scan thousands and even millions of compounds to identify those that activate dendritic cells, whic...Plant genes identified that can form basis for crops better adapted to environmental conditions
... First of all, the researchers developed a special method − the Lateral Root-Inducible System (LRIS) − with which they are able to have capillary roots grow in a controlled manner. They studied all the genes that are connected with the formation of capillary roots and compared them with the comp...