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Tag: "method" at biology news

Light therapy may combat fungal infections, new evidence suggests

...i-fungal drug treatments, might offer an effective method to combat a variety of fungal infections, particularly those of the skin or nails, said HHMI investigator Joseph Heitman, M.D., James B. Duke professor of molecular genetics and microbiology and medicine at Duke. Light therapy is now used for medica...

Computational Method Speeds Mapping of Cell Signaling Networks

...from Stanford, MIT and Harvard has developed a new method for charting cellular signaling networks quickly a... cells was analyzed using a powerful computational method called Bayesian network modeling. Bayesian analysis uses statistics to determine associations and de...

Researchers find new genes necessary to make embryo

... embryos develop. Using RNA interference (RNAi), a method for identifying the function of genes, the researchers almost double previous estimates of how many genes are required to make an embryo. Their study focused on the genes expressed by the mother and imparted to the egg, ready to be used during the ea...

Scientists identify molecule that regulates well-known tumor suppressor

...of Toronto and colleagues used a genetic screening method in fruit flies and identified the molecule DJ-1 as a PTEN suppressor. In studies with mammalian cells, low levels of DJ-1 correlated with decreased PKB/Akt activity, while increased DJ-1 led to activation of PKB/Akt and enhanced cell survival. In ca...

Newly discovered pathway might help in design of cancer drugs

...pment of new anti-cancer drugs and therapies. The method could enable future doctors to target treatment more precisely, rather than directing chemotherapeutic medication or radiation to tumors through a scattershot approach, said Marc Greenberg, a chemistry professor in the university's Zanvyl Krieger Sch...

Strongest proof yet found for prion hypothesis

...ril 21, the UTMB researchers describe the use of a method they developed called "protein misfolding cyclic amplification" (PMCA) to vastly accelerate the activity of a small number of prions taken from infected hamsters and placed in test tubes containing healthy brain proteins. When the healthy proteins ha...

First frozen egg baby born in Canada

...sable. This problem has now been resolved by a new method of rapid freezing called vitrification developed at McGill by Dr. Ri-Cheng Chian, Scientific Director of the McGill Reproductive Centre at the MUHC and Dr. Tan. Each egg extracted from the ovaries of the patient is drawn into a protective device, inv...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

...earchers looked beyond traditional techniques to a method of freezing cells called vitrification. This cryopreservation technique allows the eggs to be cooled fast enough that the transformation from liquid to solid is instantaneous. No ice crystals form and the consistency resembles a viscous glassy state....

Bioelectronic ‘signatures?hold key to DNA mutations

A new method to identify DNA mutations may shepherd in an era o...vidual differences across the human genome. Wang’s method allows for an accurate, ultra-sensitive, rapid and low-cost identification of these SNP variants. “...

Study: 'homemade' gene expression technology unreliable

...icroarray platforms, we have a relatively reliable method with which to assess gene expression, we can do so reproducibly within an individual laboratory, and we can be confident that a similar result would be obtained if the experiment is repeated elsewhere," Spencer said. Gene chips contain tens of thous...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...his novel delivery system is a powerful and simple method to induce gene silencing, with the potential to move to clinical trials," said Hu, who presented the results at the 96th Annual Meeting here of the American Association for Cancer Research. In recent years, scientists have been intrigued by the pote...

Double triumph in stem cell quest

... be a much easier way to create matching ESCs. His method starts with an existing human ESC line. The nuclei...Verlinsky has applied for a patent on the stembrid method (US 2004/0259249). But he insists that he does not intend to stop other researchers using the method...

Marine sponge yields nanoscale secrets

... in the laboratory. The research team developed a method for coupling small, inexpensive synthetic molecules (that duplicate those found at the active center of the bio-catalyst of the marine sponge) onto the surfaces of gold nanoparticles. They showed that when two populations of these chemically modified...

Friendly bacteria in humans may protect against HIV

...lactobacilli may provide a safe and cost-efficient method for preventing the spread of HIV, says Tao. "This method can protect infants against HIV in breast milk and women against HIV upon sexual contact unobtrusive...

Doctors closer to using gene analysis to help trauma patients

...ttings ?an important hurdle to overcome before the method is routinely used in emergency rooms and intensive...cal noise??differences attributable to the testing method ?was not significant, suggesting that profiling gene reactions may provide meaningful information to...

Oldest fossil human protein ever sequenced

... species. As ancient DNA rarely survives, this new method opens up the possibility of determining these relationships in much older fossils which no longer contain DNA. The research presents the sequence for the bone protein osteocalcin from a Neanderthal from Shandivar Cave as well as osteocalcin sequence...

Could microbes solve Russia's chemical weapons conundrum?

...compounds of reaction masses is a biotechnological method that pro-vides maximum environmental safety, since the pollutants are naturally degraded to innocuous products such as carbon dioxide and water, as well as microbial biomass," said Dr. Ermakova. ### Article: "Microbial degradation of the detoxifica...

Study uncovers bacteria's worst enemy

...lp make bacterial bioremediation a more widespread method for cleaning up sites contaminated with actinides ...s that bacterial bioremediation can be a preferred method for cleaning up actinide contamination, we've never really known whether or not radioactivity or che...

Secret of smallpox's success may lead to bioterror cure

...target virus. Though perhaps controversial, such a method could ultimately provide effective protection from some of humankind's most challenging viral enemies. Jacob's current attempt to develop a post-exposure smallpox vaccine is also not with its challenges. Because of the extreme dangerousness of the s...

Cellular Defects in Premature Aging Disease are Reversible

...progeria can be reversed, meaning his laboratory's method could be used some day in the future as a therapeutic strategy. The fact that a progeria reversal can be achieved in multiple cell types, and that the cells can return to normal, independent of cell division, bolsters this possibility. "Some tissues ...

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