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Tag: "melanomas" at biology news

Sun exposure early in life linked to specific skin cancer gene mutation

...ust how these mutations contribute to the cause of melanomas has been a mystery. A new clue comes from scienti...0 years old, may specifically increase the risk of melanomas with BRAF gene mutations. A different mutation, on the NRAS gene, was found in patients who had sun ...

Rising skin cancer rates are more likely to affect wealthy people, says 12-year review

... wealthier areas and increased levels of malignant melanomas and basal cell carcinomas.” The team looked at ...em to affect squamous cell carcinoma. Malignant melanomas showed the greatest increase over the 12-year study period, with a 48 per cent rise in patients and ...

Molecular differences between early and advanced melanomas could provide new drug targets

...cule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically ...nding this key molecular difference between radial melanomas that spread on the surface of the skin and melanomas that grow vertically and invasively could provi...

Why don't all moles progress to melanoma?

...lifetime. Scientists know that 30 percent of all melanomas begin in a mole. They know that 90 percent of moles contain cancer-causing mutations. What scientists didn't know is how melanocytes stop these mutations from triggering the development of cancer. Maria S. Soengas, Ph.D., and other scientists in th...

Speeding discovery of the 'human cancer genome'

...ound. Further study of that common region in mouse melanomas that independently developed their invasive abilit...tly expressed at higher levels in metastatic human melanomas compared to primary melanomas. Drugs aimed at Nedd9 might therefore prevent the skin cancer's spr...

Can dogs smell cancer?

...nfirmed the ability of trained dogs to detect both melanomas and bladder cancers. The new study, led by Michael McCulloch of the Pine Street Foundation in San Anselmo, California, and Tadeusz Jezierski of the Polish Academy of Sciences, Institute of Genetics and Animal Breeding, is the first to test whether d...

Characterizing Skin Cancer by Microarrays

...the transition from radial to vertical growth, the melanomas lost the expression of certain molecules, resultin...phase, which implies that both radial and vertical melanomas can metastasize. The authors identified over 2,000 genes that distinguished the stages of melanoma p...

Study of genomic DNA leads to new advances in cancer diagnostics

...e authors also used flow cytometry to characterize melanomas of varying invasiveness. Further study will be required to determine the specificity and sensitivity of these methods before they are used in the clinical setting. Physicians and researchers alike know that how a cancer cell interacts with its micro...

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