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Tag: "mechanistic" at biology news

Natural vitamin E tocotrienol reaches blood at protective levels

... but it is still too soon to tell for humans. More mechanistic and outcomes studies are warranted." In the first study, collaborating scientists at Wayne State University fed participants 400 milligrams of a time-release formulation of a supplement containing primarily TCT. Researchers collected blood samples...

miRNA-mediated silencing of mRNAs

...e for Developmental Biology-Tuebingen) provide new mechanistic insight into gene silencing by miRNAs Their paper will be featured on the cover of the July 15th issue of G&D, and also will be made available online in advance on 7/3. MicroRNAs (miRNAs) are a novel class of small regulatory RNAs that silence ...

Looking to a new era in bee research

...tic bases of honey bee venom allergens, along with mechanistic insights into the remarkable longevity of queen honey bees and sperm stored in the spermatheca. The HBGSP has united a broad range of scientists, from leaders in human genomics and bioinformatics to members of diverse disciplinary and organism-ba...

Plants' role in global warming re-examined

...itself. The development, testing and adoption of a mechanistic and bio-chemical model of plant respiration are needed. To more reliably project plant respiration and climate-carbon feedbacks in a future climate, this modeling must incorporate response to temperature, including acclimation, at time scales from mi...

USC team reveals structure of APOBEC family protein

..."This three-dimensional structure offers the first mechanistic analysis of any of the APOBEC enzymes at the molecular level. These proteins are important for understanding a number of critical biological processes, such as the generation of high-affinity antibodies in response to a virus or other infection," sai...

A wolf in sheep's clothing: Plague bacteria reveal one of their virulence tricks

...dramatic result," he says. "Not only did we have a mechanistic explanation, but we could connect what we were seeing in animal studies all the way down to what was happening at the atomic level." ...

Mars mission Risk 29: Scientists research ways to reduce radiation-induced brain damage

...Norfolk, Va., proteomic aided investigation of the mechanistic basis for HZE-induced cognitive impairment and the development of diagnostic biomarkers David Chen, University of Texas Southwestern Medical Center, Dallas, mechanisms of the repair of HZE-induced DNA double-strand breaks in human cells Albert ...

How fish mend a broken heart

...h heart. "This study gets at some of the important mechanistic questions about how they rebuild the heart, and some of the key factors that contribute." In contrast to zebrafish, the cardiac damage and scarring caused by heart attacks is a major killer among humans, making "the inability to replace damaged car...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

...r molecular and cellular research and studying the mechanistic and therapeutic targets which have made the recovery observed in this study possible. ...

Molecular motors and brakes work together in cells

... have shown how MAPs and motors work together in a mechanistic way," says Tran. "This is important and it will make other people who study microtubules rethink how they study the cell." ...

New imaging technique tracks traffic patterns of white blood cells

...opy (IVM) has contributed enormously to the recent mechanistic advances in leukocyte trafficking," wrote Mount Sinai School of Medicine researchers lead author Elaine Y. Chiang, Andres Hidalgo, Jungshan Chang and Paul S. Frenette of the Department of Medicine’s Immunobiology Center and Black Family Stem Cell Ins...

Executable biology -- Computer science sheds light on animal development

...plying the techniques of computer engineering to a mechanistic diagram describing the development of the Nematode C. elegans, a group of researchers in Switzerland has been able to tease out what laboratory experiments have not ?how and when the crucial cross-talk between cellular signaling pathways takes place ...

New findings challenge established views on human genome

...etwork model of the genome “poses some interesting mechanistic questions” that have yet to be answered. Other surprises in the ENCODE data have major implications for our understanding of the evolution of genomes, particularly mammalian genomes. Until recently, researchers had thought that most of the DNA se...

Migration alert -- How tumor cells home in on the lymphatic system

A Swiss-based research team has published a new mechanistic description of how tumor cells migrate to the lymphatic system in the early stages of tumor metastasis. This new understanding holds significant potential for developing anti-metastasis therapies. Scientists know that tumor cells spread via the lym...

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