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Tag: "measure" at biology news

New, automated tool successfully classifies and relates proteins in unprecedented way

...describe a protein's location in a cellimage. SLFs measure both simple and complex aspects of proteins, suchas shape, texture, edge qualities and contrast against backgroundfeatures. Like fingerprints, a protein's SLFs act as a unique set ofidentifiers. Using a set of established SLFs, Murphy then developed ...

Drug That 'Tags' Decision-making Areas Of The Brain May Aid

...hiatry and human behavior,developed Nifrolidine to measure a subtype of nicotine receptors in theliving brain by using an imaging technique, positron emissiontomography, more commonly known as PET scans. After proving the drug’seffectiveness, Mukherjee believes the drug will have implications forother condit...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...ctrometer is an instrument that can quantitatively measure the concentration of hundreds of proteins from a s..., the researchers say. “Are we going to be able to measure what we want to measure??Baggerly asks. “Given issues in technology and a lack of standards, I think...

New species from old data

...ctrometer is an instrument that can quantitatively measure the concentration of hundreds of proteins from a s..., the researchers say. “Are we going to be able to measure what we want to measure??Baggerly asks. “Given issues in technology and a lack of standards, I think...

Cracking the olfactory code in bees

...ctrometer is an instrument that can quantitatively measure the concentration of hundreds of proteins from a s..., the researchers say. “Are we going to be able to measure what we want to measure??Baggerly asks. “Given issues in technology and a lack of standards, I think...

Signaling protein builds bigger, better bones in mice

...ctrometer is an instrument that can quantitatively measure the concentration of hundreds of proteins from a s..., the researchers say. “Are we going to be able to measure what we want to measure??Baggerly asks. “Given issues in technology and a lack of standards, I think...

Researchers reveal the infectious impact of salmon farms on wild salmon

...contentious debate. It is the first to isolate and measure the impact of a fish farm on sea lice outbreaks in wild salmon. The study combined new field techniques that allowed comprehensive, individual observations of over 5,500 young wild pink and chum salmon over 60 km of migration route; an enormous data ...

Gene variations explain drug dose required to control seizures

...een a drug's toxic and therapeutic dose, used as a measure of the drug's relative safety for a particular treatment. Similarly, appropriate doses of carbamazepine take time to determine because of the drug's variable affects on patient metabolism and its potential neurologic side effects. The team identifi...

UCSD researchers maintain stem cells without contaminated animal feeder layers

...eeder layers were developed but this added another measure of complexity to the culture system, Hayek noted. In recent studies in Wisconsin and Massachusetts, new feeder layers were developed, but they did not entirely eliminate the use of animal products. In the Hayek study, the animal-derived feeder layers...

Scientists develop new color-coded test for protein folding

...ks on the same principle as ordinary pH tests that measure the acidity of water, is described in the March 2005 issue of the journal Chemistry and Biology. "What we've developed is a simple and inexpensive sensor for determining when a protein changes its conformation," said study co-author Richard N. Zare,...

Open microfluidic and nanofluidic systems

...ould have a well-defined geometry by which one can measure the precise amount of liquid contained in them; they should be able to confine variable amounts of liquid; and they should be accessible in such a way that one can add and extract liquid in a convenient manner. An appealing design principle for such...

Development of portable infectious disease detector

... fertilitydetector that can be used in the home to measure sperm motility with anaccuracy comparable to laboratory analyses."I'm thrilled at how well the VIIBRE and PRIA technologies mesh," saysJohn P. Wikswo, professor of biomedical engineering, physiology andphysics at Vanderbilt and director of VIIBRE. "W...

Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers

...nserted fine tubes into the spiracles of a moth to measure not only how much carbon dioxide the moth released... and doing it in a way that shows they know how to measure oxygen," Bradley said. "Their behavior indicates they are regulating oxygen." Bradley and Hetz will...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

...ral causes. The researchers used several tests to measure memory and learning. They found that growth-hormone-deficient rats had impaired learning ability compared to normal animals of the same age. A similar pattern occurred in memory tests. "The presence of growth hormone and IGF-1 are required for optim...

An entropy-based gene selection method for cancer classification using microarray data

...genes. A merit called "uncertainty" is employed to measure the relevance and the redundancy of the genes. In order to find a more representative subset of features, an iterative procedure is adopted that incorporates an initial clustering followed by data partitioning and the application of the algorithm to ...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

...said. Given that the components of amyloid fibrils measure only billionths of a meter and are floating in a d...ions by retracting the tip of their AFM, which can measure changes in force at the atomic scale. Pulling back the tip can induce a measurable tug on the chemic...

Devising Nano Vision for an Optical Microscope

... the optical microscope might be able to image and measure features smaller than 10 nanometers—a tiny fraction of the wavelength of visible light. In a preliminary test of the embryonic technique, NIST scientists used violet light with a wavelength of 436 nanometers to image features as small as 40 nanomete...

UF Researchers Map Bacterial Proteins That Cause Tooth Loss

...IT. Once separated, mass spectrometry was used to measure each protein’s mass and charge, identifiers as unique to proteins as the whorls of fingerprints are to people. The spectrometry measurements were fed into a computer database to create a computational model of the P. gingivalis proteome, resulting i...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

...other drugs of abuse. Using DNA microarrays, which measure the activity of more than 10,000 genes simultaneously, together with large databases of other biological information, researchers were able to identify several genes regulated by alcohol that may play a role in determining genetic differences in beha...

PCRM develops world's first cruelty-free insulin assay

...s first cruelty-free insulin assay, a test used to measure insulin levels in individuals with diabetes. The assay, which uses no animals, was developed as part of PCRM's ongoing clinical trials to test the effects of a low-fat, vegan diet on patients with type 2 diabetes. "We only had two options available ...

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