U of M researcher examines newly emerging deadly disease
...d sloughing of skin. Purpura are skin lesions that may be many centimeters in diameter caused by the leak... the consideration that the staphylococcal disease may be more common than the two prior illnesses. Patients should also be given early administration of a...Study finds more than one-third of human genome regulated by RNA
... class of molecule once relegated to the sidelines may be one of theprincipal players in regulating cellular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this type of gene control is much more widespread thanpreviously appreciated," says Whitehead Member a...Live Recombinant Adenovirus Vaccine Technique Explored
...ombinant HPV vaccines currently in clinical trials may not be ideal in poorer countries because they are expensive and require multiple immunizations. The Hopkins researchers developed their vaccine prototype using canine oral papillomavirus (COPV), which behaves similarly to HPV. Research by other scie...Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
...anned for mid-February. "This experimental device may make it possible for those with retinitis pigmentosa to have a much better quality of life," says Dr. Aaberg. "We are excited to be able to participate in this clinical trial as part of Emory Eye Center's ongoing research and surgical procedures to f...... robotic vehicle. They now know that a whale fall may host even more species than a hydrothermal vent—ma...pecies off Sweden and now think these zombie worms may occur worldwide. Because of their ability to break down lipids in cold water, these animals and the...NYU researchers simulate molecular biological clock
... class of molecule once relegated to the sidelines may be one of theprincipal players in regulating cellular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this type of gene control is much more widespread thanpreviously appreciated," says Whitehead Member a...Leukemia Drug Breakthrough Study In New England Journal Of Medicine
...dependent. The defective 5q chromosome abnormality may be linked to other serious cancers, including leukemias and small cell lung cancer. In another finding of the same study, all the patients with the 5q deletion who became transfusion independent also went into cytogenetic remission, meaning that the...Mitochondrial DNA mutations play significant role in prostate cancer
...thanthose with normal ntDNAs, suggesting that this may be an importantcontributory factor in the mitochon...hondrial DNA is inheritedfrom your mother, so this may explain those familial cases that are notpassed from father to son, but rather through the unaffecte...Gene therapy converts dead bone graft to new, living tissue
...cess calcium. In an average year, a healthy person may remove and rebuild 10 percent of his or her bone structure. This process of teardown and rebuilding is triggered in the dead bone when Schwarz paints it with the genetically modified virus. New blood vessels begin to grow around and into the bone sp...Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
...roduce a toxin that makes infection moresevere. It may lead to the design of new toxin inhibitors. “Blocking orinterfering with a bacterium’s “detection?mechanism, should preventtoxin production and limit the severity of infection,?says MichaelGilmore, PhD, lead author of the study, and currently directo...Researchers reveal the infectious impact of salmon farms on wild salmon
...s Volpe. "For the migratory runs we studied, there may be very little time left." ...Molecular machine may lead to new drugs to combat human diseases
...s previously believed to have no function actually may play specialized roles in cell behavior. While humans have introns, they don't have Group I introns. Many pathogens that cause human diseases, however, do have Group I introns, including the HIV opportunistic infections pneumocystis, a form of pneum...Jefferson Virologists Coax HIV Out of Hiding
...ege of Thomas JeffersonUniversity in Philadelphia, may have found a way to bring HIV out ofhiding. They h...T3, a monoclonal antibody. He suspectssuch strains may be from an unknown viral reservoir in the blood. “IL-7may teach us something,?he says. “We’re not su...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...affect human nerve cell development--knowledgethat may one day provide clues about such neurological myst...l development,"says Reinisch. "Fluctuations in PKA may influence not only neuronalmaturation but also how neuronal networks are constructed duringdevelopme...Female sex hormones play a vital role in defense against sexually transmitted diseases
... exposure to sexually transmitted viral infections may be very different than those that may be useful in vaccination strategies," said Kaushic. "There is of course the flip side to this as we...Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
...d Slack, "after diagnosis, gene therapy with let-7 may be a way to alleviate or slow it down." This work arose from Slack's basic research in the department of molecular, cellular and developmental biology on the nematode round worms, C. elegans. He found that these worms require let-7 RNA for normal de...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...affect human nerve cell development--knowledgethat may one day provide clues about such neurological myst...l development,"says Reinisch. "Fluctuations in PKA may influence not only neuronalmaturation but also how neuronal networks are constructed duringdevelopme...An HIV Protein Plays a Surprising Role in Gene Activation
...assembly, the authors are careful to note that Tat may well stimulate assembly in addition to promoting transcription elongation. And it may be this resourcefulness that makes Tat such a potent activator—and HIV so hard to control. (For more...Mouse brain tumors mimic those in human genetic disorder
...overies: New blood vessels and immune system cells may be essentialto the initial formation of tumors and therefore may be promising drugtargets; and brain images often used to determine the need fortreatment may not act......0 years old. The researchers believe the findings may bolster the “Out-of-Africa?hypothesis that suggests we all trace to an ancient line that first evolved in Africa and then displaced other hominids as recently as 50,000 years ago. Ian McDougall of Australian National University (ANU), Frank Brown of...