High-tech research shows cocaine changes proteins and brain function
...all of the proteins and then using high-throughput mass spectrometry which allowed the accurate identifcation of thousands of proteins simultaneously, Hemby said. The unbiased nature of the technology enables the determination of novel proteins and pathway involved in disease. Using post-mortem brain t...Major cancer study aims to identify protein markers for early-stage disease
...l work to establish the best method for conducting mass spectrometry in the context of cancer biomarker di...thin given blood samples. The need to standardize mass spectrometry is great. Currently, the technology produces varying results in different labs. Researc...With record resolution and sensitivity, tool images how life organizes in a cell membrane
...er Weber and Ian Hutcheon, both experts in imaging mass spectrometry at the Lawrence Livermore National La...experiments. That machine is a highly specialized mass spectrometer, which analyzes the mass of small molecular ions formed when a focused ion beam runs ac...Scientists identify 36 genes, 100 neuropeptides in honey bee brains
...bee genome sequence, as well as bioinformatics and mass spectrometry, Sweedler and collaborators from the ...rements of bee brains using an extremely sensitive mass spectrometer. Some of the genes were found because they resembled genes discovered in other species,...MIT nanoparticles may help detect, treat tumors
...ers and to study the "triggers" that turn a benign mass in the body into a cancerous tumor. Nanoparticles also hold the promise of carrying medicines that could kill cancer cells, replacing radiation or chemotherapy treatments that cause negative side effects such as hair loss or nausea. The researchers...Far more than a meteor killed dinos
...ng two thirds of all species in one of the largest mass extinction events in the history of life. It's tha... "The Chicxulub impact could not have caused the mass extinction," says Princeton University paleontologist Gerta Keller, "because this impact predates th...'Fruit fly dating game' provides clues to our reproductive prowess
...ng two thirds of all species in one of the largest mass extinction events in the history of life. It's tha... "The Chicxulub impact could not have caused the mass extinction," says Princeton University paleontologist Gerta Keller, "because this impact predates th...A giant among minnows: Giant danio can keep growing
... the fish.? Indeterminate growers increase muscle mass both by recruiting new muscle fibers (hyperplasia) and by increasing the size of the existing muscle fibers (hypertrophy). Many fish species exhibit indeterminate (hyperplastic) growth. In this first phase of the study, the researchers found that h...For super-obese patients, duodenal switch beats gastric bypass
...ass (RYGB) by all measures in patients with a body mass index (BMI) of at least 50. These patients typically carry at least 150 pounds more than their ideal weight. In this study, patients undergoing duodenal switch were significantly more likely to achieve and maintain successful weight loss--defined ...Humpback whales have brain cells also found in humans
...l abilities of this mammal. Although brain to body mass ratio, a rough measure of intelligence, is lower for baleen whales such as the humpback compared to toothed whales such as dolphins, the structure and large brain size of baleen whales suggests that they too have a complex and elaborate evolutionary ...Buildup of damaged DNA in cells drives aging
...wn as we get older, contributing to loss of muscle mass and bone density, the investigators systematically compared the gene expression pattern of their progeroid mice to normal old mice to look for other similarities. What they found was a striking similarity pattern between the progeroid and normal-aged...NASA study: Alaskan fires affected Houston air quality in 2004
...ounder on the Aqua spacecraft. They tracked an air mass from the region of forest fires in western Canada and eastern Alaska on July 12-13, 2004, and followed it as it traveled across Canada, through the mid-western United States and into the Houston area on July 19. "We found that with the arrival of th...Dinosaurs -- stones did not help with digestion
... rough in the stomachs during the experiments. The mass of the stones then corresponded on average to one per cent of the body mass of the birds. 'Whereas occasionally stones were found together with sauropod skeletons, we don't ...Plague proteome reveals proteins linked to infection
...boratory used proteomic techniques called accurate mass and time tag mass spectrometry and clustering analysis to compare abundance changes in 992 proteins under four differe...Too mellow for our predatory world
...os Islands to the cruise ship market. With growing mass tourism, the situation is getting more difficult. The National Park Management is considering raising the entry fee from the currently charged $100 to $500 in order to reduce the number of visitors - possibly the only possibility to create sustainabl...Experimental cancer drugs counter muscle deterioration seen in muscular dystrophy
... study for breast cancer, restored skeletal muscle mass and prevented the impaired function characteristic of muscular dystrophies. Importantly, these restored muscles showed an increased resistance to contraction-coupled degeneration--the primary mechanism by which muscle function declines in Duchenne mu...HIV exploits competition among T-cells
...The winners ?the T cells that the body produces in mass quantities to fight the disease ?are the ones with the best overall record against the most recogniztable strains. Among the losers, however, there may be T cells that better control the other less recognizable, but still deadly, strains. "Once the...Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes
...d with decreased sexual function, decreased muscle mass and strength, infertility, increased fatigue, depression and reduced bone density," Dr. Gupta said. "However, we could not conclude from this study that dioxin exposure did lead to any of these adverse affects in the veterans in the study." The st...Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack
...d to find out whether other interventions, such as mass pre-vaccination of the general public, pre-vaccina...nd Human Services. "Earlier studies recommended mass pre-vaccination of the general population to protect against a smallpox attack. None of us on the co......o repair and maintain higher levels of lean tissue mass present in some athletes and individuals may all affect an individuals B-vitamin requirements, said Manore. "Many athletes, especially young athletes involved in highly competitive sports, do not realize the impact their diets have on their perform...