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Tag: "marrow" at biology news

Researchers identify new weapon to fight deadly bacterial sepsis

...sing immune-suppressive therapy for organ and bone marrow transplants, and receiving high-dose chemotherapy for cancer. Young children and elderly people are also at a higher risk for the condition because of their weaker immune systems. Now, Assistant Professor Kota V. Ramana and Professor Satish Srivas...

Vaccination with embryonic stem cells prevents lung cancer in mice

...ed a significant decline in adult pluripotent bone marrow stem cells ?both potential adverse responses to the vaccinations. Prof Eaton said: "We think the results from the carcinogen-initiated cancers are probably the most important, as they are closer to the 'real-life' model of the development of cance...

Intravenous gene therapy protects normal tissue of mice during whole-body radiation

...asmid liposome (MnSOD-PL) gene therapy on the bone marrow during whole-body irradiation. The researchers found that in a control group of mice that received an initial 9 Gy dose of radiation there was 80 percent survival at 30 days compared to 93.3 percent survival during the same length of time for an expe...

Lost in the labyrinth

...ular kinds of stem cells disappeared from the bone marrow of the mice. Others were too frequent. Bone marrow cells didn't develop into myeloid and red blood cells. B- and T-cells were also blocked at early sta...

Molecular 'marker' on stem cells aids research, perhaps therapies

...found on the surface of certain stem cells in bone marrow that give rise to fat, cartilage and bone. These s...omponent of bone marrow; the vast majority of bone marrow is made up of hematopoietic stem cells, which give rise to blood and immune cells. Dr. Rita Perlin...

German researchers develop first non-invasive test to measure skin aging

...host disease, which occur when the tissues of bone marrow transplant patients are attacked by immune cells coming from the donor. "Perhaps the technique could help monitor the progress of the disease, or the success of a treatment," Dr. Koehler said. Testing the effectiveness of anti-aging cosmetic products...

Cloned mice created from fully differentiated cells, a milestone in cloning research

... hematopoietic stem cells, which are found in bone marrow and give rise to all red and white blood cells, and progenitor cells. Granulocytes are well characterized white blood cells unique for their segmented nuclei and the numerous granules in the cells' cytoplasm. Surprisingly, the granulocytes were the...

New imaging technique tracks traffic patterns of white blood cells

...s of white blood cells in the small veins and bone marrow of mice. "Intravital micropscopy (IVM) has contributed enormously to the recent mechanistic advances in leukocyte trafficking," wrote Mount Sinai School of Medicine researchers lead author Elaine Y. Chiang, Andres Hidalgo, Jungshan Chang and Paul S....

Research project tackles 'regeneration' gap

... of self-renewal that exist within our brain, bone marrow and blood ?with scientists who study how tissues and limbs develop in a variety of organisms. "A salamander can be injured to the point that it loses its limbs or part of its spinal column, yet a few weeks later you’ll see it scurrying across you...

MIT bioengineer advances survival, promise of adult stem cells

...l types. For example, stem cells found in the bone marrow develop into blood cells, bone cells and other con...s encourage the survival and proliferation of bone marrow mesenchymal stem cells grown outside of the body. The work offers hope that one day, stem cells r...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...hymal stem cells (MSC) are found in the adult bone marrow and have the potential to develop into mature hear... derived from normal, healthy adult volunteer bone marrow donors and are not derived from a fetus, embryo or animal. Because they are in an early stage of dev...

Liposuctioned fat stem cells to repair bodies

...ed tendon injuries in humans. Therapies using bone marrow stem cells, similar to fat stem cells, have achieved some successes, but the focus is shifting to fat, since the tissue is easier to access and extract than the bone marrow. That fat-based methods work is not surprising, perhaps, because adipose tiss...

Leukemic cells find safe haven in bone marrow

...se molecules released by certain cells in the bone marrow counteract the effect of that drug, according to i...earchers showed that mesenchymal cells in the bone marrow create a protective niche for leukemic cells by releasing large amounts of asparagine, an amino acid...

Are scientists making progress in being able to regenerate bone tissue?

...r bone tissue. “Bone tissue engineering using bone marrow stem cells has been suggested as a promising technique for reconstructing bone defects,?say Meijer and colleagues. Bone tissue engineering has shown success in animal studies. In their article the authors review the available data on bone tissue ...

Can engineered immune cells stop AIDS?

...are targeting hematopoietic stem cells -- the bone marrow cells that form blood cells ?to create B lymphocytes. The researchers want to reprogram these bone marrow cells by adding genes that will instruct the cells to produce rare antibodies such as B12, 4E10, 2G1...

Penn researchers replace organ in adult mice using 'single-parent' stem cells

...ere able to rescue other irradiated mice with bone marrow transplants from these animals. It is clear proof, according to McLaughlin, that uniparental cells could produce hematopoietic stem cells. In addition, McLaughlin's group found no evidence of disease linked to the transplanted cells. In another ...

Researchers first to map gene that regulates adult stem cell growth

...n cancer patients undergoing chemotherapy and bone marrow transplantation. The researchers agreed t...tem cell counts also would be valuable during bone marrow transplants, where the greatest number of stem cells are desired to help a patient recover from canc...

New cell type identified in cancer development

...Sca-1 or c-kit markers, hallmarks of normal bone marrow stem cells, nor the lineage markers most of the ca...had been partially restored by an infusion of bone marrow cells; and the third group was made up of normal, healthy mice. The results showed that the stren...

UW launches study testing adult stem cells for heart damage repair

...se blood-forming CD34+ cells from a subject's bone marrow into the bloodstream. Then, investigators use a cell separation system to remove from the subject's bloodstream a mix of cells containing the stem cells. When this process, known as apheresis, is complete, technologists further process the collect...

Scientists clone mice from adult skin stem cells

...ult hematopoetic stem cells ?the cells in the bone marrow that all blood cells are derived from ?were reported last year. But their conclusions were confusing, says Mombaerts, and there are no reports on using adult stem cells for reproducible cloning of mice that survive until adulthood. By using cells fro...

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