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Tag: "marrow" at biology news

New roles for growth factors: Enticing nerve cells to muscles

...and development of skeletal muscle, blood and bone marrow cells. The Salk study adds on more job to an already long list. "Our study emphasizes that the nervous system does not necessarily rely on an entirely new set of molecules to govern axon navigation, but instead uses growth factors already involved i...

Adult stem cell research at UB targets damaged hearts

...stigate whether transplanting the model's own bone marrow mesenchymal stem cells (MSC) -- cells that have the capacity to develop into blood vessels, as well as other types of tissues -- into the down-regulated tissue can change the myocardial adaptive responses and improve the function of the hibernating m...

Federal testing for mad cow disease a failure, law review editor says

...had their spinal cords, vertebrae, brains and bone marrow removed. But the ban was re-imposed on January 20 after a U.S. shipment was found to contain meat with banned vertebral columns still attached. It is widely believed that Prime Minister Junichiro Koizumi is under pressure to lift the Japanese ban...

Immune system police learn early and sometimes badly

...acholczyk says. All T cells are made in the bone marrow then move to the thymus as progenitor cells where they differentiate, upregulating surface receptors, which are molecules that detect different antigens. It's a brutal process ?95 percent of the cells die in the thymus primarily because they recogni...

Bone marrow may restore cells lost in vision diseases

...lenished in the test animals by transplanting bone marrow cells from normal male mice into albino females with two different types of acute RPE injury. Bone marrow contains stem cells, which have the extraordinary abilities to home in on injuries and possibly rege...

Fertility hope as study shows eggs survive in older ovaries

...that the new eggs come from stem cells in the bone marrow or the ovary, we really don't know and further experimentation is needed to find out." Dr Kerr said the phenomenon of egg regeneration in mice did not necessarily mean the same happened in humans. "But the mechanism could provide direction for ovari...

Healing the heart with bone marrow cells

...obilizes specific heart repair cells from the bone marrow to the injured heart after a heart attack. While it has long been known that bone marrow cells have the ability to clear the dead tissue after a heart attack, what has not been known until ...

OHSU study says stem cell 'fusion' occurs in tumors

...ory that fusion is what bonds stem cells with bone marrow cells to regenerate organ tissue. Scientists in t...nd that transplanted cells derived from adult bone marrow can fuse with intestinal stem cells of both normal and diseased tissue comprising the cellular linin...

A surprise about our body clock

...obilizes specific heart repair cells from the bone marrow to the injured heart after a heart attack. While it has long been known that bone marrow cells have the ability to clear the dead tissue after a heart attack, what has not been known until ...

UCLA researchers develop T-cells from human embryonic stem cells

...nic stem cells, which were incubated on mouse bone marrow support cells, which in turn converted them into blood forming cells. Those cells were then injected into a human thymus gland that had been implanted in a mouse, and the thymus then changed those blood-forming cells into T-cells. Located just above ...

New technology enables faster, more efficient cell harvest: Cell therapy meeting study

...iological samples including peripheral blood, bone marrow and umbilical cord blood. The Company is currently working with several companies in applying its filter harvest system to the development of innovative cell-based therapies in a variety of therapeutic areas, including orthopedics. "We are please...

Embryos exposed in 3-D

...iological samples including peripheral blood, bone marrow and umbilical cord blood. The Company is currently working with several companies in applying its filter harvest system to the development of innovative cell-based therapies in a variety of therapeutic areas, including orthopedics. "We are please...

Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation

... were transferred to the female mice during a bone marrow transplant from male mice. Because male DNA carries a y chromosome and female DNA does not, the gender mismatch enabled the researchers to precisely track the donor bone marrow. To deliver the gene to the arterial wall, the researchers used a "sign...

Three-in-one virus killer prevents common, often fatal infections

... The CTLs proved effective and safe in all 11 bone marrow transplant patients, who recovered completely with...ething." The research team drew cells from bone marrow donors and "trained" T-cells to target the three viruses before injecting them into transplant recip...

MIT creates 3-D scaffold for growing stem cells

... into needed body tissues or migrating toward bone marrow and other natural destinations. "What makes these designer scaffolds particularly interesting is that cells survive longer and differentiate better without additional soluble growth factors," Zhang said. "This suggests that extracellular microenvi...

Long-term cancer risk follows stem cell transplant recipients

... lineages (which originate principally in the bone marrow and circulate in the blood) are abnormal. Destroyi...the patient's own unhealthy stem cells in the bone marrow and replacing them with a compatible donor's stem cells offers the chance of cure for a disease that...

UCSD researchers create roadmap to integrin activation

...hat could be used in patients with suppressed bone marrow function, for example," said Mark H. Ginsberg, M.D., professor of Medicine at the UCSD School of Medicine. The study will be published on line in Current Biology on September 19. Integrins are a large family of adhesion molecules that promote stabl...

'Trojan Horse' agent halts bone metastasis in mice

...hly metastatic to bone, directly into the leg bone marrow of experimental mice in order to simulate a bone metastasis. A week later, they treated the animals with five staggered doses of VEGF121/rGel delivered through intravenous injections. Half of the treated mice did not develop any bone tumors, Rose...

An advanced genetic diagnostic method for multiple myeloma

...c method for multiple myeloma (MM), a type of bone marrow cancer, which permits the detection of this disease in earlier stages. The dissertation of this biologist, produced in the Department of Genetics of the School of Sciences of the University of Navarra, and in the Institute of Human Genetics of the U...

Drug can quickly mobilize an army of cells to repair injury

...ed AMD3100 can mobilize angiogenic cells from bone marrow of human patients in a matter of hours instead of ...CSF can bring these beneficial cells from the bone marrow into the bloodstream, but with G-CSF you don't see an increase in angiogenic cells until the fourth ...

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