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Tag: "marrow" at biology news

Stem cell study for patients with heart attack damage seeks to regenerate heart muscle

...ult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue...hymal stem cells (MSC) are found in the adult bone marrow and have the potential to develop into mature heart cells and new blood vessels. The MSC cells are d...

NJIT engineer poised to take stem cell research a step forward

...ratory to test if stem cells taken from adult bone marrow can be made to turn into neurons. If her research shows that the cells can turn into neurons -- the nerve cells in the body that control brain and spinal cord function -- patients with spinal cord injuries could be healed with injections of stem cell...

Single microRNA causes cancer in transgenic mouse

...ans, they are produced from stem cells in the bone marrow and then evolve through several stages before they become mature enough to create antibodies. Antibodies are proteins that sit on the surface of B cells or that are secreted by B cells that can detect the presence of foreign invaders like bacteria, v...

Findings advance use of adult stem cells for replacement bone

...ed a new way to culture adult stem cells from bone marrow such that the cells themselves produce a growth matrix that is rich in important biochemical growth factors. The research, which appears online this week in the Proceedings of the National Academy of Sciences, is notable not just because of the scie...

Measuring artery repair cells could become new heart disease test

...l progenitor cells (EPC), are produced in the bone marrow and travel to the site of arterial damage. The re...produced in high amounts by stem cells in the bone marrow as part of the process of maintaining the longer lifespans of these cells. Researchers have used ALD...

Retinol for combating leukemia cells

...onstantly dividing and they accumulate in the bone marrow impeding the formation of blood cells. In the analyses undertaken in the laboratory, it was seen that 95 % of these malign lymphoblasts died after application of retinamide. But what is the mechanism that really triggers this death? To explain the p...

Stem cell transplants improve recovery in animal models for stroke, cerebral palsy

...ween donor and recipient that is needed for a bone marrow or conventional stem cell transplant, according to company executives. Another advantage is that use of immunosuppressive drugs does not appear to be required, in contrast to other types of stem cell treatment. Animals that received MultiStem TM ...

Mutation in blood stem cells provides clues to cancer development

...s. As a result of this intrinsic defect, the bone marrow produces excessive numbers of red blood cells. "T...The disorder can also lead to scarring of the bone marrow and acute leukemia. Currently, patients are treated by bleeding them (phlebotomy) or administering ...

Bone marrow cells can become functional gut lining cells

...chers report the discovery that cells used in bone marrow transplantation can develop into new cells lining ...l Academy of Sciences. The study showed that bone marrow derived cells can differentiate into functional gastrointestinal epithelial cells after bone marrow ...

Weighting cancer drugs to make them hit tumors harder

...g toxicity to vital organs such as the liver, bone marrow and heart. Likewise, chemotherapy's stay inside tumors is brief because it flows out as rapidly as it entered. In contrast, high molecular weight chemotherapy molecules are too large to be picked up by normal blood vessels. The drugs also remain lon...

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

...ow. Because these stem cells originate in the bone marrow instead of the brain or fetal or embryonic tissue,...that the neural stem cells ?in this case from bone marrow ?were able to track to the tumor very efficiently and, like a heat-seeking missile, deliver a killer...

Stem cells can repair torn tendons or ligaments

...chymal stem cells (MSCs), which reside in the bone marrow and fat tissues, to express a protein called Smad8 and another called BMP2. When the researchers implanted these cells into torn Achilles tendons of rats they found that the cells not only survived the implantation process, but also were recruited...

U of MN uses robotic surgery techniques in cardiac cell therapy research

...in clinical research trials." Skeletal and bone marrow cells that are injected into damaged heart tissue have been shown to improve function in the left ventricle, the chamber of the heart that pumps blood into the aorta, the main artery through which oxygen-rich blood flows from the heart to the body. ...

New pathways for autoimmune treatment identified

... i NKT cells in the thymus, spleen, liver and bone marrow and severely impaired maturation of those cells in...ched the key regulatory cells come out of the bone marrow and go to the thymus where all T cells go for a process of positive and negative selection and matur...

Bones hold the key to blood renewal

...ngs, which may lead to future improvements in bone marrow transplantation and a better understanding of dise...ore balance. The team's study showed that the bone marrow response to the body's call for help involves stepping up production of osteoclasts, putting machine...

Adult stem cells are touchy-feely, need environmental clues

...mal stem cells, which regularly reside in the bone marrow as part of the body's natural regenerative mechanism, depend on physical clues from their local environment in order to transform into different types of tissue. The researchers were even able to manipulate stem cells by changing the firmness of the...

Can you hear me now? Scientists find previously unknown receptors on adult stem cells

..., researchers believed that stem cells in the bone marrow spent most of their existence in a slumber-like st...a Medical Research Foundation have discovered that marrow stem cells -- undifferentiated cells that eventually give rise to the blood cells that fight infecti...

Injection may prevent infertility in men receiving cancer chemotherapy

...lready shown that AS101 could protect against bone marrow damage and hair loss, and also sensitises the tumour to treatment", he said. The scientists divided the mice into four groups ?Taxol only, AS101 plus Taxol, AS101 only, and a control group. After 30 days they were euthanized and their testes exami...

Failure of 'scout cells' may lead to cancer in transplant patients

...ransplant patients and in up to 20 percent of bone marrow and lung transplant patients. The disease usually arises within six months to a year after transplantation, and it can have a 70- to 80-percent mortality rate. The study by VanBuskirk and her colleagues examines two types of immune cells: cells th...

Finding paves way for better treatment of autoimmune disease

...graft versus host disease, a problem for some bone marrow transplant patients when immune cells from the donor start attacking. This finding indicates a potential role for helping transplant patients keep new organs, the researchers say. Dr. Iwashima has an Alcoholic Beverage Medical Research Foundation g...

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