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Tag: "marrow" at biology news

Bone marrow stem cells may heal hearts even years after heart attacks

..., in 18 patients given infusions of their own bone marrow stem cells up to eight years after a heart attack,...ter a heart attack. The researchers harvested bone marrow from the hip bones of the patients, so there was no threat of transplant rejection. After processing...

A little telomerase isn't enough

... and people with the condition, stem cells in bone marrow that replenish the blood cells and those in the di...t for people with dyskeratosis congenita is a bone marrow transplant from an unaffected family member. But the team's new findings in mice suggest that the fa...

Pillows - a hot bed of fungal spores

...ng infectious cause of death in leukaemia and bone marrow transplant patients. Fungi also exacerbate asthma in adults. The researchers dissected both feather and synthetic samples and identified several thousand spores of fungus per gram of used pillow - more than a million spores per pillow. Fungal cont...

Clinical trial to test stem cell approach for children with brain injury

...injury with stem cells derived from their own bone marrow starting early next year at The University of Texa...ld in the study. If permission is granted, bone marrow will be extracted from the child's hip and then processed to derive two types of progenitor stem cel...

Cells from amniotic fluid used to tissue-engineer a new trachea

...has also used cells from the ear and from the bone marrow to derive cartilage cells, amniotic fluid is much more readily available. Millions of pregnant women elect to have amniotic fluid drawn to test for chromosome defects, the procedure known as amniocentesis. And when a prenatal ultrasound exam reveals ...

Compound from marine bacteria shows potential as multiple myeloma therapy

...yeloma is a currently incurable cancer of the bone marrow that causes a plunge in the production of vital red and white blood cells. Although relatively rare, it is the second most common type of blood cancer and accounts for 11,000 deaths annually in the United States. Bortezomib, approved by the Food and ...

PET imaging reveals the immune system at work

...s had been suppressed and then replaced using bone marrow from another mouse. The donor marrow included cells with genes engineered to be detectable by PET. By inducing cancer in the mice, Witte ...

Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method

...s had been suppressed and then replaced using bone marrow from another mouse. The donor marrow included cells with genes engineered to be detectable by PET. By inducing cancer in the mice, Witte ...

From one cell, many possible cures

...that will allow stem cells derived from adult bone marrow to be grown in sufficient quantities to permit far... medical procedure in which a small amount of bone marrow is extracted from his or her pelvic bone." Within that extracted bone marrow, only about one in eve...

Feds give researchers ok for safety test of adult stem cells in patients with heart disease

...ate the safety of using adult stem cells from bone marrow to treat chronic ischemia, a serious form of heart... of the procedure. It will involve injecting bone marrow stem cells at varying doses into the coronary arteries of patients suffering chronic ischemic corona...

Forgotten by evolution?

...l stem cells which had been isolated from the bone marrow of mice. What was particularly special about the process they used was that they did not add growth factors to the culture medium; the goal was to prevent the cells from differentiating prematurely. By doing so, the scientists discovered that the two...

Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

Therapy that involved bone marrow stem cells did not improve cardiac function in pat...rowth-factor protein) induces mobilization of bone marrow stem cells, according to background information in the article. Dietlind Zohlnhöfer, M.D., of the T...

Stem cells from muscles can repair cartilage

..., notes that although stem cells derived from bone marrow have been extensively investigated for the repair of cartilage defects, the current study is the first to investigate using enriched stem cells from muscle. The author states that the results are encouraging, especially the successful use of fibrin g...

Bones from blood: Scientists aim to break new ground on fractures

... cells (MSCs) in cord blood appear similar to bone marrow stem cells but they are hard to locate. We aim to ...herapies. "We also want to compare them with bone marrow and embryonic stem cells and investigate how we can turn them into bone structures for use as 3D bon...

Researchers reverse juvenile diabetes in animal model

...nd also maintains a federally funded national bone marrow HLA typing center within his lab.With this funding...r processes for molecular typing for matching bone marrow donors and recipients, the ability to identify those at risk for diabetes, an understanding of the l...

Mice studies illustrate potential of chimp/human antibodies to protect against smallpox

...sing a library of antibodies derived from the bone marrow of two vaccinia-immunized chimpanzees, the study researchers identified a pair of potent antibodies that target and neutralize the B5 protein, one of five key proteins responsible for cell-to-cell spread of infectious vaccinia virus. The researchers ...

Cell therapy slows progression of an inherited neurological disease; Improves motor skills in mice

...e is no cure; the only current treatment is a bone marrow transplant. Ernesto Bongarzone, PhD, and his colleagues at the San Raffaele Scientific Institute in Milan, Italy, transplanted cells that produce myelin into the brains of newborn MLD mice. The researchers found that the transplanted myelin-produci...

New research demonstrates bone-marrow derived stem cells can reverse genetic kidney disease

...moved, the researchers transplanted allogenic bone marrow into the knockout mouse. According to Kalluri, within a period of about four weeks, the investigators found that approximately 10 percent of the transplanted cells had incorporated into the damaged regions of the kidney glomeruli in the knockout mou...

Powerful technique for multiplying adult stem cells may aid therapies

...ers tremendous promise for treatments such as bone marrow transplants and perhaps even gene therapy. "A 30-fold increase is ten times higher than anyone's achieved before," says Lodish, senior author on the paper, which will be published January 22 online in Nature Medicine. Unlike embryonic stem ...

First SCID gene chip to be introduced at Academy meeting on immunodeficiencies

...ave attained a ninety percent success rate in bone marrow transplantation and treatment advances can cure ce.... Advances include the high success rate for bone marrow transplantation for unrelated, matched donors and treatments using gene therapy. In addition, resea...

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