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Tag: "markers" at biology news

Protein 'fingerprint' in spinal fluid could spot Alzheimer's disease

...ed not have turned out that way, several of the 23 markers that emerged from this analysis proved to be prote...ings speak to the practicality of using biological markers for discerning whether symptoms are reflective of Alzheimer's, another dementia or normal aging," Re...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

...s of the epidermal neural crest stem cells express markers for oligodendrocytes, the nerve-supporting cells that are essential for proper neuron function. She has been awarded a grant from the Biomedical Technology Alliance, a Milwaukee inter-institutional research group, to determine in collaboration with B...

First biomarker for human sleepiness identified in fruit flies

... when your target is a killer whale. Hopefully the markers we develop will make these kinds of phenomena much easier to study." ...

Inheritance outside DNA

...olon cancer, says Feinberg. Spotting epigenetic markers like lost IGF2 in humans could be used in future cancer-prevention strategies. Says Feinberg, “It could be possible to screen for colon cancer risk by looking at the epigenetic changes in colon cells of healthy people.? ...

Powerful genome ID method extended to humans

...ovide coordinates on chromosomes analogous to mile markers on freeways. Lead author Anton Valouev, a recent graduate of Waterman's lab and now a postdoctoral fellow at Stanford University, said the algorithm makes it possible to optically map the human genome. "It carries tremendous benefits for medica...

Early-stage immune system control of HIV may depend on inherited factors

...ility complex (MHC) ?proteins are also the primary markers of tissues as "self." Unique to each individual, these are the factors that need to be matched as closely as possible in organ transplants, with perfect matches only possible between identical twins. Some studies have found that HIV patients with pa...

New study aims to stop sepsis in its tracks

...iscover whether the factors can serve as molecular markers to help track organ function and recovery progress in patients. This molecular approach may also shed light on new ways to understand and treat sepsis. And consortium researchers will study the cost-effectiveness and logistics of establishing such ...

Proteins may predict lung transplant rejection

...se the dose of anti-rejection drugs when the early markers of rejection appear. Or, they may reduce anti-rejection drugs for people who do not show early signs of rejection. (Anti-rejection drugs have their own side effects, including an increased chance of developing kidney disease or malignancies.) Fina...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...GC-1alpha is one of the most reliable and specific markers of SIRT1 activity in mammals. The research team found that levels of PGC-1alpha were three-fold lower in the HCR fed mice than in the HC mice, consistent with what would be expected when SIRT1 was being activated by resveratrol. "This work demonstr...

U of MN researchers turn cord blood into lung cells

...s, they were able to find cells that exhibited key markers present in type II alveolar cells....

New imaging technique tracks traffic patterns of white blood cells

... the near-simultaneous observation of cell surface markers and microdomains." Researchers explored various mouse models including that of Sickle Cell disease which is a common inherited blood disorder in the United States, affecting 72,000 Americans according to the National Institutes of Health (NIH). Si...

Genes and genius: Researchers confirm association between gene and intelligence

...tudy, however, researchers tested multiple genetic markers throughout the gene. "If we look at a single marker, a DNA variation might influence IQ scores between two and four points, depending on which variant a person carries," Dick explains. "We did that all up and down the gene and found that the vari...

Nanoparticles can track cells deep within living organisms

...showed that the cells retained their usual surface markers and that they were still functional after the labeling process. The labeled cells were shown to migrate to and incorporate into blood vessels forming around tumors in mice. The researchers believe the cells could soon be used in clinical settings...

Improving outcomes in premature births

...of the newborn’s health including perinatal death, markers of brain damage and serious lung and bowel complications, mothers treated with nitroglycerin had significantly healthier babies. Graeme N. Smith, MD, PhD, states, "Our team is very excited about these findings. It is estimated that it costs the Ca...

Plastic that degrades in seawater could be boon for cruise industry and others

...of the newborn’s health including perinatal death, markers of brain damage and serious lung and bowel complications, mothers treated with nitroglycerin had significantly healthier babies. Graeme N. Smith, MD, PhD, states, "Our team is very excited about these findings. It is estimated that it costs the Ca...

Scientists produce neurons from human skin

...start of the experiment, the cells began producing markers and molecules associated with the transmission of nerve impulse between neurons. "This suggests the beginning of synapse formation between neurons," points out Professor Berthod. In the short term, this breakthrough might have an impact in the fie...

Gene hunters close in on Lou Gehrig’s disease

...autioned that the 34 SNPs are not guaranteed trail markers for ALS genes. “If you roll dice 555,352 times, you are bound to get lucky by chance alone on some of those throws,?he says. “The next step is to go back and figure out which of these ‘hits?are real and which are false.? Thousands of other SNPs we...

Gene study shows three distinct groups of chimpanzees

...They also devised a simplified set of about 30 DNA markers that zookeepers or primatologists could use to det...parate species of chimpanzee, and examined 310 DNA markers from each. They found four "discontinuous populations," three of common chimps plus the bonobos....

Twin studies reveal genetic components leading to cardiac and kidney disease

...The endothelium secretes several hormones that are markers of how well it is functioning. Release of one of these markers, called endothelin (ET-1), is trigged by a gene that regulates catecholamines, chemical compounds produced in the adrenal gland that are released in reaction to stress. The study measure...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...l cell line responses. "The concordance of our markers of response to lapatinib with those observed clinically suggests that the molecular markers identified in the cell line collection can be used to guide the use and testing of other approved an...

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