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Tag: "markers" at biology news

U-M scientists discover identifying markers for primitive blood-forming stem cells

...rrently, scientists must search for many different markers and use complex procedures to separate rare hemato...Cs, from other cells in a blood sample. Using SLAM markers will streamline the process considerably, says Mark J. Kiel, a student in the U-M Medical School's M...

Studies on human genome variation provide insight into disease

... variant at another locus; in other words, the two markers are "genetically indistinguishable." Dr. Lon Cardon and his colleagues describe in this month's issue of Genome Research how these "genetically indistinguishable" polymorphisms can complicate the identification of disease-related genes. "Although...

Housecat-sized Siberian tiger cubs get collared

... variant at another locus; in other words, the two markers are "genetically indistinguishable." Dr. Lon Cardon and his colleagues describe in this month's issue of Genome Research how these "genetically indistinguishable" polymorphisms can complicate the identification of disease-related genes. "Although...

Study hints at role of stem cell genes in testicular, breast cancers

... in the development of tumors or serve as valuable markers of tumor progression, the researchers say. As such...ltimately could lead to new targets for therapy or markers for diagnosis. A next step, according to the researchers, will be to "dig deeper" to determine the ...

Study reveals genomics of inflammation from severe injury

...ma, the researchers hope to identify the molecular markers that spell sepsis. The research team zeroed in on white blood cells, which help fight infection and disease and trigger inflammation. The scientists analyzed the activity of tens of thousands of genes from these cells, which were taken from the vol...

Study Unlocks Insects?Secret for Love in the Dark

...ma, the researchers hope to identify the molecular markers that spell sepsis. The research team zeroed in on white blood cells, which help fight infection and disease and trigger inflammation. The scientists analyzed the activity of tens of thousands of genes from these cells, which were taken from the vol...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

... additional breast cancer markers, as well as with markers for other cancers. They are also planning to perform animal studies, examining the sensitivity of the antibody-nanotube system in detecting cancer cells in the blood and in detecting specific types of cancer cells shed in the blood from tumors. Imm...

Genetic analysis of cavefish reveals more about evolution

...elated traits. The researchers found that genetic markers for albinism in the two groups appeared in the same location, suggesting three possibilities: the two cave populations had the same mutation in the same gene, they showed different mutations in the same gene, or they had mutations in distinct but clo...

Finding rewrites the evolutionary history of the origin of potatoes

...he cultivated potato. The scientists analyzed DNA markers in 261 wild and 98 cultivated potato varieties to assess whether the domestic potato arose from a single wild progenitor or whether it arose multiple times - and the results were clear, says David Spooner, the USDA research scientist who led the stud...

Microarray technology for tailoring breast cancer therapy

... stage and age - which are all accepted prognostic markers for breast cancer. The present lack of criteria to help tailor breast cancer treatment to individual patients indicates a need to develop new techniques for better prediction of how patients will respond to adjuvant treatments. The researchers sugge...

Ancient humans brought bottle gourds to the Americas from Asia

...oss the Americas. They then identified key genetic markers from the DNA of both the ancient gourds and their modern counterparts in Asia and Africa before comparing the plants' genetic make-up to determine the origins of the New World gourds. "For 150 years, the dominant theory has been that bottle gourds,...

Plants, too, have ways to manage freeloaders

...inary study, she, Taylor and Povich used molecular markers to identify the different strains of the bacteria Bradyrhizobia that interact with roots of the six species of lupine found on the reserve site. They then tested 10 of these strains to see which were preferred by two of the six lupine species. Worki...

Bird song changes sound alarm over habitat fragmentation

...imes and before other indicators - such as genetic markers - show any change," they say. Sharing song types - when a male replies to a rival's song with the same song sequence - with neighbours is common in birds, and is thought to act as a threat signal between males, which would explain why birds have evo...

Pregnancy drugs can affect grandkids

...imes and before other indicators - such as genetic markers - show any change," they say. Sharing song types - when a male replies to a rival's song with the same song sequence - with neighbours is common in birds, and is thought to act as a threat signal between males, which would explain why birds have evo...

Cellular scale drug delivery from the inside out

...e possible to sequentially release genes, chemical markers and other materials within cells in order to track what happens and what specific changes take place. This phase of Lin's research ties into a larger plant metabolomics project at Ames Laboratory. ...

Patterns in genome organization may partially explain how microbial cells work

... New techniques that attach fluorescent "reporter" markers to predetermined spots on chromosomes have indicated that many bacterial genes tend to be found at specific cellular locations. Patterns are not obvious in the sequences of prokaryotic genomes, which led the team led by Palsson to use signal-processi...

Researchers map of genetic variations implicated in disease

...ght common diseases will be accelerated by the new markers reported here. At an ever increasing rate, we are developing the necessary tools and sample collections to make a real difference to the study, diagnosis and, we hope, treatment of diseases such as TB, coronary heart disease, diabetes and rheumatoid ...

'Bad' enzymes may wear white hats after stroke

...Qiao Zhao used two naturally occurring proteins as markers for neurovascular remodeling.He had the group look for Egr1 and RECA-1, both of which indicate neuron and blood vessel regrowth. Rats that received an MMP inhibitor seven days after stroke had much lower levels of these proteins, indicating impaired...

Genetic study shows humans have pushed orangutans to the brink of extinction

...o hundred orangutans were identified using genetic markers called microsatellites. "We used the DNA information to simulate population history and detect evidence of a population decline," Goossens explains. "The genetic study shows that there is a high risk of extinction of the orangutan in Sabah in the n...

Cell barrier shows why bird flu not so easily spread among humans

...ognition of human receptors can serve as molecular markers for the pandemic potential of the isolates." ...

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