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Tag: "markers" at biology news

NHGRI targets 12 more organisms for genome sequencing

...nt strains of laboratory rats. SNPs can be used as markers to zero in on genetic variations that may affect an individual's risk of developing common, complex illnesses such as heart diseases, diabetes and cancer. Building a catalog of rat SNPs will assist researchers trying to find genetic variations associ...

Whole genome promoter mapping - Human Genome Project v2.0?

...easingly turning towards the idea of using genetic markers for diagnosis and prognosis, or determining personalized therapies, so-called pharmacogenetics, but we don't know how these genes are regulated or even related to each other. The identification of such a large number of promoters means that we can be...

Stem cells in bone marrow replenish mouse ovaries

...on," Tilly says. With the help of several genetic markers that are found in germ cells, the master cells tha...ood. In addition, the researchers also found these markers in human bone marrow and blood. Remarkably, the researchers found that bone marrow or blood cell tr...

Genetic links could unlock clues to leading cause of blindness

...archers pinpointed a chromosome region and genetic markers for macular degeneration in humans and rhesus monkeys, findings recently published in the online edition of the journal Experimental Eye Research. Linking the disease in monkeys to the disease in humans allows researchers to study how it progresses i...

Researchers seek to discover what really happens when a virus enters the body

...healthy cells, Duca identifies and stains relevant markers from the virus and the host. Under ultraviolet lig...esult from the spectral overlap of the fluorescent markers that Duca uses. Also, since the microscope cannot capture the entire laboratory dish at once, mult...

Most common lung cancers may begin in newly discovered cells

... of the resulting cancer cells carry the molecular markers of both of the two kinds of cells found in non-small lung cell cancers. In mice, the tumors start deep in the lung, past the trachea and the branches to the lobes. Ciliated cells that catch debris give way to the bronchiolar cells called Clara cells....

Biased reporting found in cancer prognostic studies

... so-called prognostic factors--biologic or genetic markers that may predict how a patient may fare during or after treatment, according to a new study in the July 20 issue of the Journal of the National Cancer Institute. In recent years, researchers have raced to discover and publish papers on prognostic fa...

Researchers devise new technique for creating human stem cells

...rching the fused cells for two distinctive genetic markers present in the somatic fibroblast and stem cells. The researchers were also able to further confirmed that fusion occurred by studying the chromosomal makeup of the fused cells. Their analyses showed that the hybrid cells were "tetraploid" ?meaning t...

3D Atlas Will Help Navigate The Spinal Cord

...l be based on a comprehensive use of neurochemical markers (chemoarchitecture). Many pathways in the nervous system contain a particular protein which can be demonstrated in tissue sections using a technique called immunohistochemistry that involves the use of specific antibodies. The often distinct distribu...

Elderly mice yield clues to the process of growing old

...ing process. According to the new Science report, markers of oxidative stress did not parallel the accumulation of mitochondrial genetic mutations. Instead, the group found evidence that indicated accelerated cell death, especially in tissues characterized by rapid turnover of cells, occurred as mutations m...

Nanowires can detect molecular signs of cancer, scientists find

Use of minuscule devices to spot cancer markers could lead to ultra-powerful new diagnostics Harv...d University researchers have found that molecular markers indicating the presence of cancer in the body are readily detected in blood scanned by special array...

AACR Favors 'full spectrum of stem cell research biology'

...prove evaluation of anti-cancer drugs, to identify markers for early detection of cancer, and to illuminate the path to novel, targeted treatments," said Lynn M. Matrisian, Ph.D., AACR past president and Ingram Distinguished Professor of Cancer Research at Vanderbilt University in Nashville, Tenn. "Our beli...

UQ researcher tracking key to healing the brain

...he tried and true method is to look for particular markers on the outside of the cell, but this is a long and laborious process. "What we are doing is looking at a distinguishing attribute of stem cells, which is that they are relatively quiescent, or don't divide much in relation to other cells. "This w...

Digging in the dirt for life's biochemical foundations

...adelphia, tagged nitrogen with easy-to-spot atomic markers and then watched as it traveled from soil to fungus to plant roots. Many had assumed that the fungus would play a modest role. The team found, however, that the fungus acts more like a four-lane highway than a two-track country road in shuttling the...

From a Few Wild Ancestors, a Citrus Cornucopia

...track genetic similarities between accessions. The markers -- not unlike those used in forensics for determining genetic identity and parentage -- helped the researchers identify specimens of unknown origin and differentiate between closely related species. Of the roughly 900 total accessions, about 400 of ...

New technique could alter field of mouse genetics

...especially difficult to sequence. Furthermore, the markers it carries make it easy to find. In Xu's lab, the jumping gene carried red fluorescent protein and an enzyme that changes the coat color of a white mouse to grey or black. The transposon acts as a genetic beacon, so researchers can easily track its l...

Genetic link confirmed between Polynesians and indigenous Taiwanese

...today's Polynesians, and looked for unique genetic markers that occurred in the aboriginal people. They then compared these markers to those found in mainland Chinese, Taiwanese, and other Southeast Asian peoples. Trejaut et al. fo...

High-Throughput GoMiner

...today's Polynesians, and looked for unique genetic markers that occurred in the aboriginal people. They then compared these markers to those found in mainland Chinese, Taiwanese, and other Southeast Asian peoples. Trejaut et al. fo...

Most embryos produced during IVF do not result in live births

...pre-implantation genetic diagnosis and biochemical markers of embryo viability," said Patrizio. "In addition this study should also move the field toward perfecting methods of egg production." ...

Discarded placentas deliver researchers promising cells similar to embryonic stem cells

...epithelial cells have many of the telltale surface markers that define embryonic stem cells, and also express... nervous system, and pancreatic cells with genetic markers for insulin and glycogen production. "In this first paper we sought to determine if amniotic epithe...

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