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Tag: "markers" at biology news

Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants

...ant to photobleaching thanconventional fluorescent markers and their small size make them idealfor biological imaging. The researchers then added the molecules togerminated lily pollen grains and examined them under a confocalmicroscope.This is the very first time that Quantum Dots have been utilized forlive...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...ls of inflammatory cytokines were also measured as markers of acute inflammation. Analyses showed that CVL obtained after the application of PRO 2000 gel reduced both HIV and HSV infectivity by at least 1000-fold compared to CVL obtained at baseline. The effects were highly statistically significant (p "An...

Neuronal 'traffic jam' marks early Alzheimer's disease

...findings also could ultimately lead to distinctive markers of early Alzheimer's disease that could be used in early diagnostic tests for the disorder, they said. The research team led by Lawrence S. B. Goldstein, a Howard Hughes Medical Institute investigator at the University of California, San Diego (UCSD...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...a require revision. With new molecular and protein markers now identified, patients with features that porten...," said Dr. Chiorazzi. "Once these new prognostic markers are clinically available to doctors, and after large-scale trials testing early intervention are com...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...r in human cells," saidThiele. "Current diagnostic markers for iron deficiency aren't verysensitive, unless t...level of iron deprivation, he said.With diagnostic markers in place, physicians could translate theseverity of the disease into the appropriate treatment....

Plants defy Mendel's inheritance laws, may prompt textbook changes

...een in the flowers. The researchers used molecular markers - bits of DNA that help identify and locate genes in organisms - to determine whether a plant carried normal or mutant copies of the genes. "It seems that these hothead-containing plants keep a cryptic copy of everything that was in the previous gen...

Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin

...they can use these emissive polymersomes to target markers on the surface of a specific type of tumor cells. ...olymersomes to target multiple cancer cell-surface markers in the body simultaneously. Emissive polymersomes perform much like in vivo imaging systems that us...

Chemists identify key gene in development of type 1 diabetes

.... Prediabetic individuals are those who have blood markers ?either antibodies or genetic markers ?that are predictive of the disease but are still able to produce insulin. Al-Abed and his associat...

International HapMap consortium expands mapping effort

...pe map, or HapMap, which will consist of 1 million markers of genetic variation, called single nucleotide polymorphisms (SNPs). The consortium's new goal is to build an improved version of the HapMap that is about five times denser than the original plan. This "Phase II" HapMap will take advantage of the ra...

Towards precise classification of cancers based on robust gene functional expression profiles

.... Prediabetic individuals are those who have blood markers ?either antibodies or genetic markers ?that are predictive of the disease but are still able to produce insulin. Al-Abed and his associat...

Researchers develop rapid diagnostic tool for pathogen identification

...isms. Genetic probes for pathogens were coupled to markers known as mass codes. After amplification, incorporated mass codes were detected by mass spectroscopy allowing identification of the pathogen. According to Thomas Briese, PhD, associate director of the Greene Infectious Disease Laboratory at the Mail...

Rats infected as newborns grew up vulnerable to memory problems during an immune challenge

... later, they euthenized the rats and checked brain markers of the immune response. Because it spurs an immune response without live bacteria, LPS helps to reveal how the immune system works on its own, without the complication of side effects. The team found that E. coli-infected pups later injected with LP...

HIV vaccine trial breaks ground for future research

...ological differences in immune response or genetic markers of resistance to infection could have made the vaccine more effective. Also examined in the trial were the immune responses to the vaccine. The vaccine was able to generate antibody responses in virtually all participants, and, in general, those wit...

Nanoscale Diagnostic Sets Sights on Alzheimer's

...f Alzheimer's. If the BCA process can identify the markers before symptoms develop, doctors may be able to co...mmunity thinks about molecular diagnostics and the markers they consider for many types of diseases." ?Chad Mirkin, Northwestern University Department of Chemi...

Heart repair gets new muscle

... stem cell. This is based on an absence of protein markers for skeletal muscle cells in Spoc cells, as well as the fact that Spoc-derived cells display spontaneous rhythmic beating and express cardiac markers, whether they are grown in a test tube or have migrated to injured hearts in study mice. The author...

Biomarkers isolated from saliva successfully predict oral and breast cancer

...om the fact that salivary nucleic acids or protein markers might be influenced by eating, drinking, smoking, diet or oral hygiene," said Wong. "So our goal is to provide the optimized and standardized protocol to assure consistent results." The studies are supported by grants from the U.S. Public Health Ser...

Double triumph in stem cell quest

...s derived via therapeutic cloning have the surface markers that make them compatible with the donor's immune system. The biggest question, though, is whether the stembrids really are true ESCs. Verlinsky says the cells express a number of ESC markers. His team has also shown the cells can differentiate into...

Doctors closer to using gene analysis to help trauma patients

...hy individuals in an effort to correlate molecular markers with white blood cell behavior, and ultimately, with patient outcome. Studies in healthy patients were conducted at UF, Washington University in St. Louis, the University of Rochester School of Medicine and the University of Medicine and Dentistry of...

Protein prevents detrimental immune effects of bacterial sepsis

... returning to normal by 24 hours. Higher levels of markers of inflammation, and of organ injury, were measured in annexin 1 deficient animals. Altogether, these findings implied that the protective effects of the annexin 1 pathway were activated in the first few hours following toxin administration. In fact,...

The biggest family tree ever

...mples. His team will trace people's lineages using markers encoded into DNA. The DNA samples will be analyzed...researchers to decipher the characteristic genetic markers of both parental lineages. UA is collaborating in a joint venture with Family Tree DNA, a company s...

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