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Tag: "marker" at biology news

Genetic key to growth of new arteries is identified

... the co-authors of the study. The mice carried a marker gene, beta galactosidase, that turns tissues blue. Different strains of the mice had different fragments of the MMP2 gene coupled to the so-called blue gene. Leg muscles turned blue only in the strain of mice with the specific gene fragment that turn...

Environmental tobacco smoke linked to behavior problems in children and pre-teens

...iva and hair. It is considered the best available marker of environmental tobacco smoke exposure. Dr. Yolton found a relationship between cotinine levels and increases in acting out; increases in holding things in, often manifested by anxiety and depression; increases in behavior problems as rated by pare...

New evidence questions the simple link between prion proteins and madcow disease

...ectious, or whether PrP is really just a secondary marker of the presence of the scrapie agent," says Jeffrey. His belief in this need to reappraise the fundamental understanding of prion diseases is enhanced by one more observation published in this same paper. The team pre-digested a mixture containing ...

Living taste cells produced outside the body

...sed to show that the cultured cells contain unique marker proteins characteristic of mature functioning taste receptor cells. In addition, functional assays revealed that the cultured cells responded to either bitter or sweet taste stimuli with increases of intracellular calcium, another property characteri...

Junk DNA may not be so junky after all

...equence can be tested for its ability to turn on a marker gene in zebrafish embryos. The system is a significant advance over current methods in this model species, allowing researchers to study more sequences in a shorter period of time. Using this, they identified several human enhancers able to control e...

Infused spleen cells found not to impact islet recovery and reversal of type 1 diabetes in mice

...equence can be tested for its ability to turn on a marker gene in zebrafish embryos. The system is a significant advance over current methods in this model species, allowing researchers to study more sequences in a shorter period of time. Using this, they identified several human enhancers able to control e...

GlycoFi announces the first production of antibodies with human glycosylation in yeast

... the variable domain of the antibody to a specific marker protein, such as the CD20 receptor on the surface of cancer cells, followed by 2) the recruitment of immune system "effector" cells that bind the constant domain of the antibody and destroy the cancer cell to which the antibody is bound. Research has...

Absence of critical protein linked to infertility

..., the protein's presence could become a vital gene marker for predicting uterine readiness for pregnancy. ...ch. In future studies, confirmation of C/EBPb as a marker that correctly indicates uterine readiness for implantation in the human is likely to alleviate thes...

Animal brains 'hard-wired' to recognize predator's foot movements, Queen's study suggests

... subject moves, these seemingly unstructured white marker dots become organized into meaningful images, from which observers can determine the gender, body build, emotional state, and other attributes. In this study, Dr. Troje's team used "point-light sequence" videos to display the electronically capture...

Cracking the genetic code for control of gene expression

...ory elements direct organ-specific expression of a marker gene in transgenic mice. Novel experimental and computational methods enabled genome-wide analysis of regulatory elements in several species. Studying the control of gene expression is a growing area of research at the moment, likely owing to its f...

New test to detect rare proteins in blood

...uses enzymes linked to an antibody or antigen as a marker for picking out specific proteins. For example, it...ioisotopes. Development of a test for the cancer marker Her2/neu The researchers compared detection of Her2/neu in the blood between ELISA and FACTT. Her2...

Face perception is modulated by sexual orientation

...productive partners? Facial beauty is considered a marker for reproductive fitness. Not surprisingly, recent studies have reported that facial beauty evokes activation in the brain's reward circuitry. It has been suggested that the rewarding, evolutionarily adaptive value of an attractive face can be dissoc...

New method enables gene disruption in destructive fungal pathogen

...he DNA construct includes an antibiotic-resistance marker gene, which allows for easy selection of the new mutants, as well as a short partial target gene that integrates and disrupts genes in the pathogen's genome. Richard Oliver, director of the Australian Centre for Necrotrophic Fungal Pathogens and pr...

Newly discovered killer cell fights cancer

...e group is profiling IKDC genes to find a specific marker that could help them identify a human counterpart. ...

How nice, brown rice: Study shows rice bran lowers blood pressure in rats

...s of free radicals. For example, high levels of a marker called 8-OHdG indicate biological stress and genetic damage due to oxygen-based free radicals. The researchers found that rice bran, which contains various forms of the antioxidant Vitamin E, markedly lowered the rats?levels of the peptide 8-OHdG. “...

Thinner and younger

...ess oxidative damage to their DNA, thought to be a marker of aging at the biochemical and cellular level. "This study has laid the groundwork for future research into the long-term effects of calorie restriction in humans to see whether it really can extend lifespan," Holloszy says. "It's becoming clear fr...

Mayo Clinic study finds two genes predict outcome for breast cancer patients

...e profile was previously discovered as a potential marker of relapse in hormone-receptor positive breast can...Fergus Couch, Ph.D. "Our new study shows that the marker is only useful for identifying women with a higher risk in the setting of lymph node-negative breast...

New pathways for autoimmune treatment identified

...pha-GalCer, prompted the scientists to use it as a marker to examine the status of these cells in a mouse missing the Aire gene. That Aire knockout is a good model for humans with APS1. They found significantly fewer i NKT cells in the thymus, spleen, liver and bone marrow and severely impaired maturatio...

In-home sensors spot dementia signs in elderly

...r, and that "this variability may provide an early marker that can be used to predict the later onset of dementia in a single individual." They have already begun a larger study to test that theory. Much of the hardware used in the study is simple, widely available and inexpensive. Plus, it's getting smal...

Key to early diagnosis of autism may be in the placenta

...iscovered in the placenta what may be the earliest marker for autism, possibly helping physicians diagnose t...ally the presence of trophoblast inclusions, was a marker for ASD. The multidisciplinary team of Yale researchers compared placentas from 13 children with ASD...

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