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Tag: "marker" at biology news

Newly discovered genetic disease sheds light on body's water balance

...dman developed an assay for receptor activity. One marker of this activity is an increase in the amount of cyclic AMP (cAMP) within the cell. He worked in the laboratory of pediatric endocrinologist Walter Miller, MD, using a method to determine cAMP levels in cells by using a luciferase plasmid that respon...

Fluorescing lab worms signal longer life spans

...rado at Boulder scientists have used a fluorescent marker to predict the individual life spans of identical worms that were genetically engineered to illuminate stress levels, implying living organisms have "hidden physiological states" that dictate their ability to deal with the rigors of life. According ...

Most common lung cancers may begin in newly discovered cells

...surface of BASCs, Bender Kim found another protein marker that is also present on the surface of better-studied hematopoietic stem cells. She made certain that BASCs were not stem cells of the blood or blood vessels. The BASCs passed the rigorous tests for stem cells. In response to two types of lung damag...

Looks matter to female barn swallows

...heir throats, breast and belly feathers with a red marker to enhance their feathers to match the darkest -- ...n, or left them alone or painted them with a clear marker to ensure that results were not biased by the coloring process. Then she let the pairs breed again. ...

Biased reporting found in cancer prognostic studies

...a needed cultural change within the field of tumor marker research. Citations: # Article: Kyzas PA, Loizou KT, Ioannidis JPA, Selective Reporting Biases in Cancer Prognostic Factor Studies. J Natl Cancer Inst 2005;97:1043?5. # Editorial: McShane LM, Altman DG, Sauerbrei W, Identification of Clinically Usef...

'Jumping genes' contribute to the uniqueness of individual brains

...ons Gage. "We only looked at one L1 element with a marker gene and can only say that motility is likely significantly more for endogenous L1 elements," he adds. ...

Change in gene may be underlying molecular defect in some colorectal cancers

...te that MGMT promoter methylation may qualify as a marker of the field defect in colorectal cancer," the authors write. In addition, "given the high lifetime risk of colorectal tumor development in the U.S. population, it is reasonable to propose testing to determine whether healthy persons with MGMT promot...

Protein structure key for AIDS, cell function

...unknown, when people fall ill, making human CD38 a marker for these diseases. As one example, researchers have shown that CD38 interrupts an interaction between the AIDS virus and its point of entry into cells -- a protein receptor called CD4. By looking at CD38's 3-D structure, the Cornell researchers id...

Forsyth scientists find three bacteria associated with oral cancer

...o hope that we have discovered an early diagnostic marker for the disease," said Donna Mager, DDS, PhD., Assistant Member of the Staff in the Department of Periodontology and Molecular Genetics and the principal investigator. "If future studies bear this out, it may be possible to save lives by conducting l...

New study finds how cells with damaged DNA alert the immune system

...action that leads to the increased expression of a marker recognized by the body's immune system. The new findings, to be published July 3 in an advanced online issue of Nature, shed light on a long-standing question of how the natural killer (NK) cells - which are able to attack tumors - can differentiate...

Renewed hope for Parkinson's patients

...action that leads to the increased expression of a marker recognized by the body's immune system. The new findings, to be published July 3 in an advanced online issue of Nature, shed light on a long-standing question of how the natural killer (NK) cells - which are able to attack tumors - can differentiate...

U-M scientists discover identifying markers for primitive blood-forming stem cells

...efinitely. This indicated that CD244+ cells were a marker for multipotent progenitor cells (MPPs), but not f...ls. In a third step, the team tested another SLAM marker called CD48, and found it to be expressed only on more advanced cells. It was not present on either ...

Scientists unpick genetics of first 15 minutes of life

...enome of the newly-formed organism. This genetic marker could be a useful way of tracking the genetic material an offspring inherits from either their father or mother. ...

Research Permits First-Ever Visualization of Psychological Stress in the Human Brain

... Functional Neuroimaging, provides a neuro-imaging marker of psychological stress -- which will pave the way for the development of improved strategies for preventing or correcting the long-term health consequences of chronic stress. The researchers' study appears in the November 21 online edition of Procee...

Researchers quantify more noise in gene expression

...ineered strains of yeast with a green fluorescence marker linked to a gene involved in the metabolism of the sugar galactose. The galactose gene and 10 others were chosen because they are expressed in yeast cells in high copy numbers, a feature that makes intrinsic noise in their expression statistically in...

Sperm stem cells closer to being like embryonic stem cells

...erm cells, which we achieved using the fluorescent marker and other purification methods that are different from those used by other research groups." Other UT Southwestern researchers involved with the work were Dr. Robert Hammer, professor of biochemistry and in the Green Center, and research technicians...

Forgotten by evolution?

...tractile apparatus. In addition, the expression of marker genes for cardiomyocytes, like the alpha-myosin-heavy-chain protein, could only be shown after the scientists performed what is known as epigenetic reprogramming (epigenetic reprogramming is a synonym for heritable modifications of the DNA others tha...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

...ate specific membrane antigen (PSMA) ?a well known marker for prostate cancer which is over-expressed on certain prostate epithelial cells. Experimental results described at ECCO 13 show that these bioconjugates successfully and selectively adhered to PSMA-positive prostate cancer cells, while PSMA-negative...

Open Source Biotechnology alliance for international agriculture

...recombination), new plant breeding methods such as marker assisted selection, or even true breeding hybrids of crop species that would allow farmers in developing countries to use hybrid seed year after year. Adds Jefferson, "Scientists and farmers need better options for problem solving, that meet their pr...

Researchers use 'trickery' to create immune response against melanoma

...ate specific membrane antigen (PSMA) ?a well known marker for prostate cancer which is over-expressed on certain prostate epithelial cells. Experimental results described at ECCO 13 show that these bioconjugates successfully and selectively adhered to PSMA-positive prostate cancer cells, while PSMA-negative...

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