New type of rejection blocker protects kidneys after transplant
...re co-principal authors of the study. The results mark an important step toward proving the value of a new type of treatment based on blocking the immune system's reaction to a transplanted organ without hampering the body's ability to fight diseases and infections, according to Vincenti, clinical profes...Microscopic brain imaging in the palm of your hand
...ed to excite the fluorescent-dye molecules used to mark the tissue. The technique gets rid of the background haze and reduces scattering, because molecules outside the area of interest are much less likely to absorb a pair of photons simultaneously and fluoresce in response. While two-photon microscopy ...Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes
...-independent for longer than 1 year. "Our results mark a distinct advance in islet transplant efficacy. We not only achieved insulin independence using islets from only 1 donor pancreas [as compared with 2 to 4 in another trial], we also achieved superior glycemic control (as evidenced by normal results ...UCSD research reveals mechanism involved with type of fatal epilepsy
...e have mutations in malin that render it unable to mark laforin for degradation. This increase in laforin may lead to Lafora disease through aberrant glycogen metabolism. This work establishes a few testable models as to the molecular mechanism of the disease. Dixon and colleagues are currently designing...First technology to remove prions that cause vCJD from blood launched
...pathy (BSE), also known as Mad Cow Disease. The CE mark means the new prion reduction filter meets pan-European essential requirements for safety of medical devices. "The availability of our prion reduction filter is a seminal event heralding a new era in blood safety," says Eric Krasnoff, Chairman and C...Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
...ts in test tubes, lanosterol led other proteins to mark reductase for destruction by attaching a protein called ubiquitin in a process called ubiquitination. Ubiquitination is a common mechanism for stimulating protein degradation. Cholesterol itself had no such effect on reductase, even at much greater c...South America's vast pantanal wetland may become next everglades, UNU experts warn
... for development and agriculture. In a message to mark World Water Day, March 22, UNU says the Pantanal provides enormous environmental services by storing and purifying water, providing storm protection and flood mitigation, and stabilizing the local climate, particularly rainfall and temperature. Toda...First real-time view of developing neurons reveals surprises, say Stanford researchers
...hing their final identity. Still, the experiments mark the first time researchers have been able to watch neurons in an entire region of the brain as they fire one by one in real time. The technical savvy involved in monitoring neurons will allow researchers to conduct experiments that were previously no...New studies suggest airborne SARS transmission is possible
...e SARS outbreak there in March 2003. Their results mark the first experimental confirmation of the presence of the SARS virus in the air of an infected patient's hospital room. The authors cautioned that their results do not document any cases of airborne transmission of the SARS virus from one person to...New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
... About Tiling Arrays: Affymetrix "tiling" arrays mark a shift in the way microarrays are designed and interpreted. By using a neutral approach to array design, tiling arrays include all non-repetitive sequence from a given genome, not just the hand-selected regions that were previously thought to be imp...Researchers reveal the infectious impact of salmon farms on wild salmon
...raphically disparate regions. "At about the 30 km mark from the farm, those lice become reproductive," says Volpe. "In effect, the farm has exported its lice generating properties ?a cyclical event establishing the potential for re-infections up and down the coast. As the abundance of lice increases, we ...... ligase complex that adds ubiquitin to proteins to mark them for destruction by the cell. Fbw7 recognizes a destruction signal on certain proteins that need to be degraded and brings them in close proximity to the enzymes that attach ubiquitin. The proteins recognized by Fbw7 play key roles in cell divisi...