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Tag: "mark" at biology news

'Insulator' helps silence genes in dormant herpes virus

...aring in the May issue of the Journal of Virology, mark the first time an insulator has been identified in a virus and may lead to ways to develop strategies to manipulate the virus. Insulators, also known as boundary elements, are DNA segments that work to prevent a gene from being influenced by the ...

Scientists find new genetic clue to cause of Alzheimer's disease

...with the disease. They identified 29 variants that mark relatively short segments of DNA where disease-causing changes could lie. The study did not, however, identify specific genetic changes that result in Alzheimer's. Richard Mayeux, M.D., of Columbia University, Lindsay Farrer, Ph.D., of Boston Unive...

Scientists to track impact of Asian dust and pollution on clouds, weather, climate change

...tute. "This mouse model and its future variants mark the first use of genetically produced light activa... experiments in cell culture, the Duke experiments mark the first time the gene controlling its action has been inserted into the genetic makeup of a living...

Common algae helps illustrate mammalian brain electrical circuitry

...tute. "This mouse model and its future variants mark the first use of genetically produced light activa... experiments in cell culture, the Duke experiments mark the first time the gene controlling its action has been inserted into the genetic makeup of a living...

Experience affects new neuron survival in adult brain; study sheds light on learning, memory

... After injecting mice with a chemical used to mark proliferating cells, the researchers exposed the animals to an "enriched cage" environment, containing tunnels, shelters, and a running wheel. After several weeks, the researchers again exposed the mice in the same enriched experience. They discover...

With fruit fly sex, researchers find mind-body connection

...wing-shaking come-ons and flirtatious flights that mark male and female fly courtship. Results are published in Nature Genetics. "What we found here, and what is becoming increasingly clear in the field, is that genetic interactions that influence behavior are more complex than we thought," said Mic...

Math model predicts cancer behavior

...istant sites), Quaranta said, because these events mark "the critical transition of a tumor that in the end will be lethal for the patient." A tumor that does not penetrate the surrounding tissue can often be surgically removed with curative success. "When a patient comes in with a tumor, we'd like to u...

Transplanted brain cells hold promise for Parkinson's disease

...covery holds up; he’s already past the three-month mark and to date, recovery is stable. While the rats needed immunosuppression because they received human cells, Dr. Borlongan says humans would not. About a half-million Americans have Parkinson’s disease. Typically the disease does a lot of damage t...

An AIDS-related virus tricks cells to become tumors, new Penn study finds

...e way the tumor suppressors p53 and VHL work is to mark a key protein that controls the blood supply in a tumor mass. Once marked, this protein called hypoxia-induced factor 1a (HIF-1a) is degraded through ubiquitylation before it can start the process of activating genes responsible for inducing growth o...

Reef warns of sea level rise

...reef, lying several metres above today's high tide mark at Foul Bay near Margaret River, points to the high point of the last major sea level rise. Investigators from the ARC Centre of Excellence for Coral Reef Studies (CoECRS) consider the reef ?the most southerly coral reef yet known ?is a harbinger o...

Protein splicing upsets the DNA colinearity paradigm

... produces antigenic peptides; the 'red flags' that mark cells for destruction by the immune system. The immune system attacks 'foreign' cells - be they tumor cells, virally infected, or donated by another person - when T lymphocytes recognize antigenic peptides displayed on the cell surface. The antig...

From a lowly yeast, researchers divine a clue to human disease

...ng a single length of DNA are separated by gaps to mark boundaries. As the polymerase reaches the end of a gene, Sen1 flips a switch and knocks it off the DNA track. The group, led by Brow and Eric Steinmetz, compared normal yeast to a strain with a mutated form of Sen1 that does not see the stop signa...

Lab-on-a-chip could speed up treatment of drug-resistant pneumonia

...d specifically to certain strains of bacteria, and mark them with fluorescent dyes of different colors. The dyes color-code cells from known strains. A microscope monitors the viable cells -- those that are still reproducing -- and the rate at which they duplicate helps to identify their species. In th...

Successful lung cancer surgery not enough to break nicotine dependence in many smokers

... Patients who were able to quit by the one year mark waited longer to attempt to smoke again, or never began again. In fact, more than one in four patients who smoked after surgery were nonsmokers at the 12-month follow-up, he said. "Perhaps for these patients, lung cancer surgery was a wake-up call t...

A fisheye view of the deadliest breast cancer

...beled human MDA breast cancer cells in two ways to mark the parental MDA cells and to mark tumor cells that overexpress RhoC. They injected both tumor cell lines into the immune-suppressed f...

Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm

...he significance of the findings. "This molecular mark is required at a critical time leading up to genom...lso, there seems to be a similarity in the way the mark is used in organisms as different from each other as yeast and mammals, suggesting that compaction h...

Fighting like a girl or boy determined by gene in fruit flies

...lying sexual differences in behavior. The findings mark a milestone in an unlikely new animal model for understanding the biology of aggression and how the nervous system gives rise to different behaviors. "Aggression is a very serious problem in society, and it's a problem with a biological and geneti...

MIT finds most complex protein knot ever seen

...th another protein called ubiquitin. "It's a death mark for the protein," said Leonid Mirny, an author of the paper and an associate professor in the MIT-Harvard Division of Health Sciences and Technology. Once the "death mark" is applied, proteins are shuttled to a cell structure called a proteasome, w...

Beauty and the brain

...he phrase "easy on the eyes" may hit closer to the mark than we suspected. Experiments led by Piotr Winkielman, of the University of California, San Diego, and published in the current issue of Psychological Science, suggest that judgments of attractiveness depend on mental processing ease, or being "e...

UWM brain research supports drug development from jellyfish protein

...rwood believes his company is at about the 12-year mark in the typical 15-year cycle for a new drug to be developed. Moyer's research centers on brain changes that occur as a result of aging. Specifically, he is interested in the part of the brain called the hippocampus, which is responsible for formin...

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