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Marburg virus disease in Angola - update

As of 29 March 2005, the Ministry of Health has reported a total of 124 cases and 117 deaths in Cabinda, Luanda and Uige. All these cases had originated in Uige Province. Ten of these cases have been laboratory confirmed by the Centers for Disease Control and Prevention (CDC), Atlanta, USA. . The team from WHO, including experts from the Inter-country programme for southern Africa, the Regional O...

Marburg haemorrhagic fever in Angola update

As of 20 April, the Ministry of Health in Angola has reported 266 cases of Marburg haemorrhagic fever. Of these cases, 244 were fatal. In Uige Province, which remains the epicentre of the outbreak, 253 cases, of which 233 have been fatal, were reported as of 21 April. . .. The international response to the outbreak in Angola began one month ago, on 22 March. The features of Marburg haemorrhagic f...

WHO suspends Marburg work, appeals for new funds

As of 7 April, 205 cases of Marburg haemorrhagic fever have been reported in Angola. Of these, 180 have died. Zaire Province has reported its first 6 cases, bringing the number of affected provinces to seven, all concentrated in the north-western part of the country. . .. WHO staff in Uige were notified tod...

Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus

Using multi-disciplinary analysis that included cognitive, neurophysiologic, virologic, and molecular techniques, the team found both a low-level viral infection in the brain and immune cells that had infiltrated the brain in order to protect against the virus. . "As in the rest of the body, in the brain immune cells achieve a level of control of the virus, but are unable to clear the infection,...

Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease

Researchers in the Greene Infectious Disease Laboratory at Columbia University's Mailman School of Public Health, the Centers for Disease Control and Prevention, and the Caribbean Primate Research Center have discovered a key mechanism by which the Filoviruses, Ebola and Marburg, cause disease. The identification of an amino acid sequence in Filoviruses that results in the rapid depression of im...
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