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Tag: "mapping" at biology news

Single microRNA causes cancer in transgenic mouse

... malignant growth. He and his colleagues have been mapping the activity of dozens of miRNAs in various types of normal and malignant tissues for several years. Earlier studies showed that miR155 was unusually active in some types of leukemia and lymphoma, and that its presence indicated a poorer prognosis in...

Biologists develop genome-wide map of miRNA-mRNA interactions

...he most recent issue of Current Biology. In mapping miRNA targets, the research team examined the function of the genome of C. elegans, the first animal species whose genome was completely sequenced and a model organism to study how embryos develop. Using PicTar, an algorithm developed at NYU, the res...

UF scientists trace origin of shark's electric sense

...ectroreceptors." Dye tests are a classical way of mapping cell movements during development, and have been used to explore the origins of limbs and brain cells. In the current research, scientists used genetic markers to trace neural crest cells. "Dye labeling would be interesting and further test the idea...

Chemical signaling helps regulate sensory map formation in the brain

...raphic connections by providing a lateral directed mapping force." ...

Drug discovery team to explore newly discovered deep-sea reefs

... Mark Grasmueck and geologist Gergor Eberli, began mapping deepwater habitats off Miami and Bimini using an a...d also in a variety of other research programs for mapping purposes, but the Miami researchers believe this is the first time an AUV has been used to map deep...

Deep-water discovery

...d by Professors Grasmueck and Gregor Eberli, began mapping deepwater habitats off Miami and Bimini using adva...ve this is the first time an AUV has been used for mapping deepwater coral reefs. AUVs have been frequently used in oil exploration and in a variety of other ...

New light microscope sharpens scientists' focus

...a single fluorescent protein, which limits them to mapping a single target protein per sample. "Right now the resolution is wonderful, but it's all single-label stuff. Knowing where one protein is located is nice," Betzig said, "but what you really want to know is where multiple proteins are in relation to o...

New flood-tolerant rice offers relief for world's poorest farmers

...peline." Results of this study Using genetic mapping techniques, the research team identified acluster of three genes that appeared closely linked to the biologicalprocesses that either make rice plants vulnerable to flooding orenable them to withstand the total submergence that occurs duringflooding. ...

The brain, traffic and nano-circuits -- e-Science takes on major challenges

...ting. The challenges are, understanding the brain, mapping the detailed environmental impact of traffic and designing future generation nano-scale electronic circuits. The Engineering and Physical Sciences Research Council (EPSRC) and other funding partners have awarded more than £13m to three, 3-4 year pro...

Gene discovery opens door to tackling disease

...as this gene had not been characterised during the mapping of the human genome," said Professor Leedman. "What's exciting is that SLIRP has the potential to shut down oestrogen in breast cancer cells and testosterone in prostate cancer cells. "Most of those cancers depend on the hormones to stay alive, so ...

Large-scale genomics project will hunt genes behind common childhood diseases

...ved in many of the company's important genome-wide mapping and association studies over the past several years, and served as director of Respiratory, Inflammatory and Pharmacogenomics Research, vice president of Clinical Sciences, and later as vice president of Business Development. "Our goals for the Cent...

Nice guys do finish first in lizards' evolutionary race

...volutionary puzzle that we needed to solve." Gene mapping revealed that the male blue-throats who buddied up are not even remotely related ?yet still share many genes. Somehow, McAdam said, the altruistic lizards know they're working to pass on their genes, even though their partners aren't family. The tag-...

With record resolution and sensitivity, tool images how life organizes in a cell membrane

...at this research allowed the first high-resolution mapping of chemical features in a region of interest. ''We can analyze a few percent of one component in the presence of other components...It's exquisitely sensitive.'' Sensitivity is important because cell membranes are not pure materials. ''We're looking...

Researchers map spread of pathogens in the human body

...ge have discovered a new, more accurate, method of mapping how bacteria spread within the body, a breakthrough that could lead to more effective treatments and prevention of certain bacterial infections. Dr. Pietro Mastroeni, Professor Duncan Maskell at the Centre for Veterinary Science, and their teams ha...

Caterpillars tell us how bacteria cause disease

...ew method. It has given us a cheap and easy way of mapping bacterial virulence factors across an entire genome. This will allow us to rapidly and inexpensively bridge the enormous knowledge gap that has grown in the post-genomic era where it has become possible to sequence a whole bacterial genome without ne...

Mapping the mouse genome

...olymorphism (SNP) data that resulted from physical mapping of the mouse genome, the authors were able to track the patterns of inheritance of >10,000 SNPs in both groups of mice. Next, they were able to calculate their relative genetic locations based on how frequently they co-occur. They used this infor...

Powerful genome ID method extended to humans

...discovery has extended the reach of a novel genome mapping method to humans, potentially giving cancer biolog...e massive amounts of data created by a restriction mapping technology known as "optical mapping." Restriction maps provide coordinates on chromosomes analogous...

Discovery of the first resistance gene to rice yellow mottle virus

...led by a single recessive gene. Subsequent genetic mapping identified a fragment of chromosome 4 containing the resistance gene. Data from rice genome sequencing have been extremely useful for research on this fragment to find out if one gene rather than another could confer resistance to RYMV. Data from the...

NASA satellite data helps assess the health of Florida's coral reef

... resilient to adverse conditions and bleaching. By mapping these healthy regions, officials can then attempt to simulate those conditions elsewhere. Climate conditions, especially sea surface temperatures, are considered a major factor in coral reef health. Bleaching events typically peak when waters reach...

Living view in animals shows how cells decide to make proteins

...g in health and disease," he added, "this anatomic mapping of splicing decisions may give us considerable insight into the many human diseases associated with improper regulation of splicing."...

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