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Tag: "manipulate" at biology news

Research identifies protein that signals flowering in squash plants

...lant. In day-neutral plants, it is not possible to manipulate flowering by altering the daylength. By contrast, obligate SD plants will remain in the vegetative state until and unless inducing conditions (such as long nights) occur, and therefore they represent the ideal system for experimental manipulation to ...

Hormone helps mice 'hibernate,' survive starvation

...western and the study’s senior author. “We hope to manipulate this hormone-receptor signaling pathway to craft the next generation of drugs to combat human obesity and other conditions.” Mammals on the brink of starvation normally shift their main fuel source from carbohydrates to stored fats, promoting surv...

Researchers demonstrate way to control tree height

...ity have used genetic modification to successfully manipulate the growth in height of trees, showing that it’s possible to create miniature trees that look similar to normal trees – but after several years of growth may range anywhere from 50 feet tall to a few inches. This is a “proof of concept” that tree he...

St. Jude study shows genes play an unexpected role in their own activation

... this work is that one day it might be possible to manipulate CREB’s co-factors to treat disease. “A drug that blocked the specific co-factors CREB needs in the liver to trigger activity of genes that make glucose could reduce blood levels of this sugar in people with diabetes,” Brindle said. “But at the same t...

'Insulator' helps silence genes in dormant herpes virus

...irus and may lead to ways to develop strategies to manipulate the virus. Insulators, also known as boundary elements, are DNA segments that work to prevent a gene from being influenced by the activation or repression of its neighbors. About a dozen different insulator elements have been identified in organi...

Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness

...less well. The key now is to determine how best to manipulate these ubiquitous receptors, together with nitric oxide for the treatment of human diseases." "In broad terms, the results of these experiments present a novel role for nitric oxide in regulating the activity of G-protein coupled receptors," Lefkow...

Magnetic computer sensors may help study biomolecules

...ches like those in computers also might be used to manipulate individual strands of DNA for high-speed applicati...me. Optical tweezers, which use lasers to trap and manipulate biomolecules, tend to be slow and limited in force, and the particles need to be micrometer sized or...

Researchers attach genes to minichromosomes in maize

... to add numerous genes onto one minichromosome and manipulate those genes easily because they are all in one place, Birchler said. Genetic modification with traditional methods is more complicated because scientists have little control over where the genes are located in the chromosomes and cannot stack multipl...

First demonstration of new hair follicle generation in an animal model

...reated by the wound-healing process can be used to manipulate hair-follicle regeneration, leading to novel ways to treat hair loss and hair overgrowth. These findings go beyond just a possible treatment for male-pattern baldness. If researchers can effectively control hair growth, then they could potentially...

Danish researches solve virus puzzle

...veloped optical tweezers which can investigate and manipulate molecules at the nano-meter scale. Using a tightly focussed laserbeam this instrument can grab the ends of the RNA tether and follow the process of how the pseudoknot is mechanically unfolded. A crucial slip of the cellular motor In their inv...

New success in engineering plant oils

...c pathways that produce these oils to find ways to manipulate the accumulation of fats using genetic techniques." The researchers focused on an enzyme known as KASII that normally elongates fatty acid chains by adding two carbon atoms. The longer 18-carbon chains are more likely to be acted on by enzymes tha...

Nanotechnology meets biology and DNA finds its groove

...here we want it to be. It is important that we can manipulate it with such fidelity." The system, says Schwartz, promises bench scientists a convenient and easy way to make large numbers of individual DNA molecules accessible for study. The ability to quickly get lots of molecules lined up for sequencing and...

A genetic 'gang of 4' drives spread of breast cancer

... patients as being associated with lung metastasis manipulate blood vessels to give them an advantage both in the primary tumors and in the lung," he said. Two drugs already on the market act directly on proteins produced by the genes Massagué’s group had been studying. Cetuximab is an antibody that blocks th...

Link found between immune system and high plasma lipid levels

... to determine whether we can use this technique to manipulate the immune response and have a favorable impact on lipid metabolism." Using an assortment of engineered and non-engineered mice, the researchers looked specifically at the role of T cells (white blood cells that play a key role in immunity). They ...

Bacteria control how infectious they become, study finds

...e changes,?Svetlov said. “Rather, bacteria seem to manipulate the protein, to play around with it. Too much RfaH will kill a cell, while too little would prevent it from infecting any living being. “We think that RfaH is responsible for more than making a microbe infectious,?he continued. “Actually seeing wh...

Liver regeneration may be simpler than previously thought

...cription factors are known to be more difficult to manipulate than the other identified proteins. Since the transcription factors were not present in regenerating livers, it might be easier to stimulate liver regeneration by only activating the other identified proteins. "These results are very encouraging,...

Shedding new light on proteorhodopsin

...tify the most efficient forms of the protein, then manipulate microbial genomes through the addition or deletion of key genes. ...

ATR checkpoint-activating DNA structure

...Dr. Cimprich. "The ability to precisely define and manipulate the nature of the checkpoint activating structure in an experimental system will enable us to control, quantitative and probe checkpoint signaling responses in unprecedented ways." Using Xenopus egg extracts as a cell-free system, the researchers ...

Wheat can fatally starve insect predators

...would be from genes that the fly larvae ordinarily manipulate so plants will produce useful nutrients for the in...oxin gene and inserted into the cells. When larvae manipulate the promoter, they would receive gut-altering lectin instead of nutrients. To advance their inves...

Researcher to study astronaut bone loss for space biology agency

...nauts," Long says. "We hope to find that we can manipulate the IGF-1 system to accelerate rehabilitation, not only among astronauts but among a broad range of patients," says Bikle. "We might also learn how to prevent bone loss from taking place." Long concludes, "I am excited and honored to contribute to...

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