Tag: "manganese" at biology news

Enzyme delivered in smaller package protects cells from radiation damage

...at intravenous gene therapy delivery of the enzyme manganese superoxide dismutase (MnSOD) could protect mice from whole body irradiation, and in preparation for a potential clinical trial of systemic MnSOD in humans, the University of Pittsburgh and Stanford researchers, led by Joel S. Greenberger, M.D., profe...

Better insight into brain anatomical structures

... have now developed a new MRI contrast agent using manganese oxide nanoparticles that produces images of the an... Magnetic resonance images after injection of the manganese oxide nanoparticles gave a view into different areas of the mouse brains—in excellent resolution. "W...

Study warns deep-sea mining may pose serious threat to fragile marine ecosystems

...n to the oceans in the 1970s, and interest grew in manganese nodules that exist on the surface of the ocean flo... boundaries. While studies of proposed undersea manganese mining in the equatorial region of the Pacific found the risks to outweigh the benefits, says Halfar...

Researchers uncover protection mechanism of radiation-resistant bacterium

...t metal concentrations, pointing to high levels of manganese and low iron levels as possible influences on cell...ial species contained approximately 300 times more manganese and three times less iron than the most sensitive species. In the new study, which examined the func...

Intravenous gene therapy protects normal tissue of mice during whole-body radiation

..., mice were used to test the protective effects of manganese superoxide dismutase plasmid liposome (MnSOD-PL) gene therapy on the bone marrow during whole-body irradiation. The researchers found that in a control group of mice that received an initial 9 Gy dose of radiation there was 80 percent survival at 30 ...

Jumping gene could provide non-viral alternative for gene therapy

...sposons to deliver a radio-protective gene, called manganese superoxide dismutase, to potentially protect normal tissue from radiation damage," Dr. Kaminski says. In cancer, he suspects gene therapy will focus on this type of modification of normal tissue for protective purposes as well as manipulating the ...

Gene therapy prevents the onset of diabetic symptoms in mice

...d rain also increases levels of the trace nutrient manganese in the soil, which can be toxic to trees in higher doses. By year four and five, manganese in the leaves had declined to healthier levels. In addition, seed production and the density and siz...

Acid rain causing decline in sugar maples, say researchers

...d rain also increases levels of the trace nutrient manganese in the soil, which can be toxic to trees in higher doses. By year four and five, manganese in the leaves had declined to healthier levels. In addition, seed production and the density and siz...

Plants reveal a secret and bring researchers nearer a cleaner future

... into molecular oxygen. This complex contains four manganese and one calcium atoms that are known to be at the centre of the catalytic reaction. Five intermediate states have been proposed in the process of photosynthesis - a cycle known as "Kok cycle"- but only four had been proved until recently. With the he...

Does manganese inhaled from the shower represent a public health threat?

...ous system. The damage may occur even at levels of manganese considered safe by the Environmental Protection Ag...million people in the United States are exposed to manganese levels that our study shows may cause toxic effects." The study is the first to show the potential ...

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