Molecular trigger for Huntington's disease found
...the researchers found that the p53 increase causes malfunctions in mitochondria. What's more, they found that this p53 increase induced by the abnormal HD protein greatly increases cell death. The researchers also found effects of the abnormality in p53 in whole animals. They found that deleting p53 suppresses d...When nerve cells can't make contact
...do not mature. The researchers assume that similar malfunctions are experienced by autistic patients. Autism is one of the most common psychiatric illnesses. Around 0.5 percent of all young children have a syndrome belonging to the "autistic spectrum". The main symptoms of this developmental malfunction are de......erstand paxillin’s many interactions because their malfunctions have been linked to a variety of cancers, tumor metastasis, and other disease processes. Tumor-causing versions of signaling molecules may attach to paxillin and disturb the normal adhesion and growth factor signaling steps required for controlled pr...